| Literature DB >> 27178924 |
António J Ribeiro1, Flávia R Lucena de Souza2, Janira M N A Bezerra2, Claudia Oliveira3, Daniela Nadvorny2, Monica F de La Roca Soares2, Lívio C C Nunes4, Edson C Silva-Filho4, Francisco Veiga5, José L Soares Sobrinho2.
Abstract
The development of delivery systems using natural polymers such as gums offers distinct advantages, such as, biocompatibility, biodegradability, and cost effectiveness. Cashew gum (CG) has rheological and mucoadhesive properties that can find many applications, among which the design of delivery systems for drugs and other actives such as larvicide compounds. In this review CG is characterized from its source through to the process of purification and chemical modification highlighting its physicochemical properties and discussing its potential either for micro and nanoparticulate delivery systems. Chemical modifications of CG increase its reactivity towards the design of delivery systems, which provide a sustained release effect for larvicide compounds. The purification and, the consequent characterization of CG either original or modified are of utmost importance and is still a continuing challenge when selecting the suitable CG derivative for the delivery of larvicide compounds.Entities:
Keywords: Cashew gum; Chemical derivatives; Delivery system; Physicochemical properties; Purification; Submicron particle
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Year: 2016 PMID： 27178924 DOI： 10.1016/j.carbpol.2016.02.042
Source DB: PubMed Journal: Carbohydr Polym ISSN： 0144-8617 Impact factor: 9.381