Literature DB >> 27147727

Detection of Aspergillus fumigatus in Blood Samples from Critically Ill Patients in Intensive Care Units by Use of the SeptiFast Assay.

Joerg Steinmann1, Jan Buer2, Peter-Michael Rath2.   

Abstract

We retrospectively analyzed the performance and relevance of the SeptiFast assay in detecting Aspergillus fumigatus DNA in whole blood samples from 38 critically ill intensive care unit (ICU) patients with probable or proven invasive aspergillosis (IA) and 100 ICU patients without IA. The assay exhibited 66% sensitivity, 98% specificity, a 93% positive predictive value, and an 88% negative predictive value. A. fumigatus DNAemia was associated with poor outcome.
Copyright © 2016, American Society for Microbiology. All Rights Reserved.

Entities:  

Mesh：

Substances：

Year:  2016        PMID： 27147727      PMCID： PMC4922108          DOI： 10.1128/JCM.00478-16

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


  16 in total

1.  Multiplex PCR for rapid and improved diagnosis of bloodstream infections in liver transplant recipients.

Authors:  Peter-Michael Rath; Fuat Saner; Andreas Paul; Nils Lehmann; Eike Steinmann; Jan Buer; Joerg Steinmann
Journal:  J Clin Microbiol       Date:  2012-04-04       Impact factor: 5.948

Review 2.  Accuracy of LightCycler(®) SeptiFast for the detection and identification of pathogens in the blood of patients with suspected sepsis: a systematic review and meta-analysis.

Authors:  Paul Dark; Bronagh Blackwood; Simon Gates; Danny McAuley; Gavin D Perkins; Ronan McMullan; Claire Wilson; Daniel Graham; Kate Timms; Geoffrey Warhurst
Journal:  Intensive Care Med       Date:  2014-11-22       Impact factor: 17.440

3.  PCR in diagnosis of invasive aspergillosis: a meta-analysis of diagnostic performance.

Authors:  Marios Arvanitis; Panayiotis D Ziakas; Ioannis M Zacharioudakis; Fainareti N Zervou; Angela M Caliendo; Eleftherios Mylonakis
Journal:  J Clin Microbiol       Date:  2014-08-13       Impact factor: 5.948

4.  A clinical algorithm to diagnose invasive pulmonary aspergillosis in critically ill patients.

Authors:  Stijn I Blot; Fabio Silvio Taccone; Anne-Marie Van den Abeele; Pierre Bulpa; Wouter Meersseman; Nele Brusselaers; George Dimopoulos; José A Paiva; Benoit Misset; Jordi Rello; Koenraad Vandewoude; Dirk Vogelaers
Journal:  Am J Respir Crit Care Med       Date:  2012-04-19       Impact factor: 21.405

5.  Combined real-time PCR and galactomannan surveillance improves diagnosis of invasive aspergillosis in high risk patients with haematological malignancies.

Authors:  Thomas R Rogers; Charles Oliver Morton; Jan Springer; Eibhlin Conneally; Werner Heinz; Claire Kenny; Susanna Frost; Hermann Einsele; Juergen Loeffler
Journal:  Br J Haematol       Date:  2013-03-11       Impact factor: 6.998

6.  Invasive aspergillosis in two liver transplant recipients: diagnosis by SeptiFast.

Authors:  J Steinmann; J Buer; P-M Rath; A Paul; F Saner
Journal:  Transpl Infect Dis       Date:  2009-02-05       Impact factor: 2.228

7.  Prospective multicentre PCR-based Aspergillus DNA screening in high-risk patients with and without primary antifungal mould prophylaxis.

Authors:  J Springer; M Lackner; D Nachbaur; M Girschikofsky; B Risslegger; W Mutschlechner; J Fritz; W J Heinz; H Einsele; A J Ullmann; J Löffler; C Lass-Flörl
Journal:  Clin Microbiol Infect       Date:  2015-09-21       Impact factor: 8.067

Review 8.  Galactomannan detection for invasive aspergillosis in immunocompromized patients.

Authors:  Mariska M Leeflang; Yvette J Debets-Ossenkopp; Caroline E Visser; Rob J P M Scholten; Lotty Hooft; Henk A Bijlmer; Johannes B Reitsma; Patrick Mm Bossuyt; Christina M Vandenbroucke-Grauls
Journal:  Cochrane Database Syst Rev       Date:  2008-10-08

9.  Revised definitions of invasive fungal disease from the European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group and the National Institute of Allergy and Infectious Diseases Mycoses Study Group (EORTC/MSG) Consensus Group.

Authors:  Ben De Pauw; Thomas J Walsh; J Peter Donnelly; David A Stevens; John E Edwards; Thierry Calandra; Peter G Pappas; Johan Maertens; Olivier Lortholary; Carol A Kauffman; David W Denning; Thomas F Patterson; Georg Maschmeyer; Jacques Bille; William E Dismukes; Raoul Herbrecht; William W Hope; Christopher C Kibbler; Bart Jan Kullberg; Kieren A Marr; Patricia Muñoz; Frank C Odds; John R Perfect; Angela Restrepo; Markus Ruhnke; Brahm H Segal; Jack D Sobel; Tania C Sorrell; Claudio Viscoli; John R Wingard; Theoklis Zaoutis; John E Bennett
Journal:  Clin Infect Dis       Date:  2008-06-15       Impact factor: 9.079

Review 10.  Aspergillus Polymerase Chain Reaction: Systematic Review of Evidence for Clinical Use in Comparison With Antigen Testing.

Authors:  P Lewis White; John R Wingard; Stéphane Bretagne; Jürgen Löffler; Thomas F Patterson; Monica A Slavin; Rosemary A Barnes; Peter G Pappas; J Peter Donnelly
Journal:  Clin Infect Dis       Date:  2015-06-25       Impact factor: 9.079
View more
  3 in total

Review 1.  Intensive care medicine research agenda on invasive fungal infection in critically ill patients.

Authors:  Matteo Bassetti; Jose Garnacho-Montero; Thierry Calandra; Bartjan Kullberg; George Dimopoulos; Elie Azoulay; Arunaloke Chakrabarti; Daniel Kett; Cristobal Leon; Luis Ostrosky-Zeichner; Maurizio Sanguinetti; Jean-Francois Timsit; Malcom D Richardson; Andrew Shorr; Oliver A Cornely
Journal:  Intensive Care Med       Date:  2017-03-02       Impact factor: 17.440

Review 2.  Fungal infections diagnosis - Past, present and future.

Authors:  Alexandre Mendonça; Helena Santos; Ricardo Franco-Duarte; Paula Sampaio
Journal:  Res Microbiol       Date:  2021-12-01       Impact factor: 3.946

Review 3.  Overview of Commercially Available PCR Assays for the Detection of Aspergillus spp. DNA in Patient Samples.

Authors:  Peter-Michael Rath; Joerg Steinmann
Journal:  Front Microbiol       Date:  2018-04-24       Impact factor: 5.640
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.