| Literature DB >> 27123534 |
Wenbo Hu1, Hengheng Ma1, Bing Hou1, Hui Zhao1, Yu Ji1, Rongcui Jiang1, Xiaoming Hu1, Xiaomei Lu2, Lei Zhang1, Yufu Tang1, Quli Fan1, Wei Huang2.
Abstract
Developing lysosome-targeting organic nanoparticles combined with photoacoustic imaging (PAI) and photodynamic therapy (PDT) functions toward personalized medicine are highly desired yet challenging. Here, for the first time, lysosome-targeting BODIPY nanoparticles were engineered by encapsulating near-infrared (NIR) absorbed BODIPY dye within amphiphilic DSPE-mPEG5000 for high-performing lysosomal PAI and acid-activatable PDT against cancer cells under NIR light.Entities:
Keywords: lysosome-targeting; near-infrared absorption; photoacoustic imaging; photodynamic therapy; theranostic nanoparticles
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Year: 2016 PMID: 27123534 DOI: 10.1021/acsami.6b02721
Source DB: PubMed Journal: ACS Appl Mater Interfaces ISSN: 1944-8244 Impact factor: 9.229