Literature DB >> 32662457

Photodynamic treatment of melanoma cells using aza-dipyrromethenes as photosensitizers.

Kelly A D F Castro1, Letícia D Costa2, Samuel Guieu2,3, Juliana C Biazzotto4, Maria Graça P M S da Neves2, M Amparo F Faustino2, Roberto S da Silva4, Augusto C Tomé2.   

Abstract

In this study, we report for the first time the use of four aza-dipyrromethenes (ADPMs) as photosensitizers for cancer PDT. The synthesis and characterization of the ADPMs and their photodynamic action against B16F10 melanoma cells were assessed. ADPM 2 is the best singlet oxygen generator and the most phototoxic (at 2.5 μM) towards B16F10 cells.

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Year:  2020        PMID： 32662457     DOI： 10.1039/d0pp00114g

Source DB:  PubMed          Journal:  Photochem Photobiol Sci        ISSN： 1474-905X            Impact factor:   3.982


  27 in total

1.  Density Functional Theory Study Predicts Low Reorganization Energies for Azadipyrromethene-Based Metal Complexes.

Authors:  Wasana Senevirathna; Cassie M Daddario; Geneviève Sauvé
Journal:  J Phys Chem Lett       Date:  2014-02-25       Impact factor: 6.475

2.  A modular synthesis of unsymmetrical tetraarylazadipyrromethenes.

Authors:  Michael J Hall; Shane O McDonnell; John Killoran; Donal F O'Shea
Journal:  J Org Chem       Date:  2005-07-08       Impact factor: 4.354

3.  Near-infrared sensing properties of dimethlyamino-substituted BF2-azadipyrromethenes.

Authors:  Shane O McDonnell; Donal F O'Shea
Journal:  Org Lett       Date:  2006-08-03       Impact factor: 6.005

4.  In vitro cytotoxicity of a library of BODIPY-anthracene and -pyrene dyads for application in photodynamic therapy.

Authors:  Susan Callaghan; Mikhail A Filatov; Huguette Savoie; Ross W Boyle; Mathias O Senge
Journal:  Photochem Photobiol Sci       Date:  2019-02-13       Impact factor: 3.982

5.  In vitro demonstration of the heavy-atom effect for photodynamic therapy.

Authors:  Aoife Gorman; John Killoran; Caroline O'Shea; Tony Kenna; William M Gallagher; Donal F O'Shea
Journal:  J Am Chem Soc       Date:  2004-09-01       Impact factor: 15.419

6.  Mechanistic insight into the formation of tetraarylazadipyrromethenes.

Authors:  Marco Grossi; Aniello Palma; Shane O McDonnell; Michael J Hall; Dilip K Rai; Jimmy Muldoon; Donal F O'Shea
Journal:  J Org Chem       Date:  2012-10-04       Impact factor: 4.354

7.  Azadipyrromethenes: from traditional dye chemistry to leading edge applications.

Authors:  Yuan Ge; Donal F O'Shea
Journal:  Chem Soc Rev       Date:  2016-05-16       Impact factor: 54.564

8.  Introducing asymmetry in tetradentate azadipyrromethene chromophores: a systematic study of the impact on electronic and photophysical properties.

Authors:  André Bessette; Mihaela Cibian; Francis Bélanger; Denis Désilets; Garry S Hanan
Journal:  Phys Chem Chem Phys       Date:  2014-10-28       Impact factor: 3.676

9.  Design, synthesis and cytotoxicity of BODIPY FL labelled triterpenoids.

Authors:  Benjamin Brandes; Sophie Hoenke; Lucie Fischer; René Csuk
Journal:  Eur J Med Chem       Date:  2019-11-06       Impact factor: 6.514

10.  Fluorescent boron complexes based on new N,O-chelates as promising candidates for flow cytometry.

Authors:  Kseniya I Lugovik; Alexander K Eltyshev; Polina O Suntsova; Leonid T Smoluk; Anna V Belousova; Maria V Ulitko; Artem S Minin; Pavel A Slepukhin; Enrico Benassi; Nataliya P Belskaya
Journal:  Org Biomol Chem       Date:  2018-07-18       Impact factor: 3.876
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