Literature DB >> 27103327

Microtubules: 50 years on from the discovery of tubulin.

Gary Borisy1, Rebecca Heald2, Jonathon Howard3, Carsten Janke4, Andrea Musacchio5, Eva Nogales6.   

Abstract

Next year will be the 50th anniversary of the discovery of tubulin. To celebrate this discovery, six leaders in the field of microtubule research reflect on key findings and technological breakthroughs over the past five decades, discuss implications for therapeutic applications and provide their thoughts on what questions need to be addressed in the near future.

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Year:  2016        PMID： 27103327      PMCID： PMC5116387          DOI： 10.1038/nrm.2016.45

Source DB:  PubMed          Journal:  Nat Rev Mol Cell Biol        ISSN： 1471-0072            Impact factor:   94.444


  6 in total

1.  Movement of microtubules by single kinesin molecules.

Authors:  J Howard; A J Hudspeth; R D Vale
Journal:  Nature       Date:  1989-11-09       Impact factor: 49.962

Review 2.  Beyond self-assembly: from microtubules to morphogenesis.

Authors:  M Kirschner; T Mitchison
Journal:  Cell       Date:  1986-05-09       Impact factor: 41.582

3.  Direct observation of kinesin stepping by optical trapping interferometry.

Authors:  K Svoboda; C F Schmidt; B J Schnapp; S M Block
Journal:  Nature       Date:  1993-10-21       Impact factor: 49.962

4.  Dynamic instability of microtubule growth.

Authors:  T Mitchison; M Kirschner
Journal:  Nature       Date:  1984 Nov 15-21       Impact factor: 49.962

5.  The mechanism of action of colchicine. Colchicine binding to sea urchin eggs and the mitotic apparatus.

Authors:  G G Borisy; E W Taylor
Journal:  J Cell Biol       Date:  1967-08       Impact factor: 10.539

6.  The mechanism of action of colchicine. Binding of colchincine-3H to cellular protein.

Authors:  G G Borisy; E W Taylor
Journal:  J Cell Biol       Date:  1967-08       Impact factor: 10.539
  6 in total
  19 in total

1.  Structure based drug design and in vitro metabolism study: Discovery of N-(4-methylthiophenyl)-N,2-dimethyl-cyclopenta[d]pyrimidine as a potent microtubule targeting agent.

Authors:  Weiguo Xiang; Shruti Choudhary; Ernest Hamel; Susan L Mooberry; Aleem Gangjee
Journal:  Bioorg Med Chem       Date:  2018-04-04       Impact factor: 3.641

Review 2.  Axon formation, extension, and navigation: only a neuroscience phenomenon?

Authors:  Shannon K Rich; Jonathan R Terman
Journal:  Curr Opin Neurobiol       Date:  2018-09-21       Impact factor: 6.627

3.  3D Tracking-Free Approach for Obtaining 3D Super-Resolution Information in Rotationally Symmetric Biostructures.

Authors:  Andrew Ruba; Wangxi Luo; Joseph Kelich; Mark Tingey; Weidong Yang
Journal:  J Phys Chem B       Date:  2019-06-10       Impact factor: 2.991

Review 4.  Coordination of microtubule acetylation and the actin cytoskeleton by formins.

Authors:  Jaime Fernández-Barrera; Miguel A Alonso
Journal:  Cell Mol Life Sci       Date:  2018-06-15       Impact factor: 9.261

Review 5.  The tubulin code and its role in controlling microtubule properties and functions.

Authors:  Carsten Janke; Maria M Magiera
Journal:  Nat Rev Mol Cell Biol       Date:  2020-02-27       Impact factor: 94.444

6.  Profilin choreographs actin and microtubules in cells and cancer.

Authors:  Morgan L Pimm; Jessica Hotaling; Jessica L Henty-Ridilla
Journal:  Int Rev Cell Mol Biol       Date:  2020-07-16       Impact factor: 6.813

7.  TTC5 mediates autoregulation of tubulin via mRNA degradation.

Authors:  Zhewang Lin; Ivana Gasic; Viswanathan Chandrasekaran; Niklas Peters; Sichen Shao; Timothy J Mitchison; Ramanujan S Hegde
Journal:  Science       Date:  2019-11-14       Impact factor: 47.728

8.  Insights into the assembly and activation of the microtubule nucleator γ-TuRC.

Authors:  Peng Liu; Erik Zupa; Annett Neuner; Anna Böhler; Justus Loerke; Dirk Flemming; Thomas Ruppert; Till Rudack; Christoph Peter; Christian Spahn; Oliver J Gruss; Stefan Pfeffer; Elmar Schiebel
Journal:  Nature       Date:  2019-12-19       Impact factor: 49.962

9.  The 3-D conformational shape of N-naphthyl-cyclopenta[d]pyrimidines affects their potency as microtubule targeting agents and their antitumor activity.

Authors:  Weiguo Xiang; Tasdique M Quadery; Ernest Hamel; Lerin R Luckett-Chastain; Michael A Ihnat; Susan L Mooberry; Aleem Gangjee
Journal:  Bioorg Med Chem       Date:  2020-11-24       Impact factor: 3.641

10.  Dual Impact of a Benzimidazole Resistant β-Tubulin on Microtubule Behavior in Fission Yeast.

Authors:  Mamika Minagawa; Minamo Shirato; Mika Toya; Masamitsu Sato
Journal:  Cells       Date:  2021-04-28       Impact factor: 6.600
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