Literature DB >> 6504138

Dynamic instability of microtubule growth.

T Mitchison, M Kirschner.   

Abstract

We report here that microtubules in vitro coexist in growing and shrinking populations which interconvert rather infrequently. This dynamic instability is a general property of microtubules and may be fundamental in explaining cellular microtubule organization.

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Year:  1984        PMID： 6504138     DOI： 10.1038/312237a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  995 in total

1.  The role of microtubules in guard cell function.

Authors:  A I Marcus; R C Moore; R J Cyr
Journal:  Plant Physiol       Date:  2001-01       Impact factor: 8.340

2.  Functional dissection and hierarchy of tubulin-folding cofactor homologues in fission yeast.

Authors:  P A Radcliffe; D Hirata; L Vardy; T Toda
Journal:  Mol Biol Cell       Date:  1999-09       Impact factor: 4.138

3.  Direct inhibition of microtubule-based kinesin motility by local anesthetics.

Authors:  Y Miyamoto; E Muto; T Mashimo; A H Iwane; I Yoshiya; T Yanagida
Journal:  Biophys J       Date:  2000-02       Impact factor: 4.033

4.  Rapid treadmilling of brain microtubules free of microtubule-associated proteins in vitro and its suppression by tau.

Authors:  D Panda; H P Miller; L Wilson
Journal:  Proc Natl Acad Sci U S A       Date:  1999-10-26       Impact factor: 11.205

5.  Assembly of an FtsZ mutant deficient in GTPase activity has implications for FtsZ assembly and the role of the Z ring in cell division.

Authors:  A Mukherjee; C Saez; J Lutkenhaus
Journal:  J Bacteriol       Date:  2001-12       Impact factor: 3.490

6.  Self-organization of a radial microtubule array by dynein-dependent nucleation of microtubules.

Authors:  I Vorobjev; V Malikov; V Rodionov
Journal:  Proc Natl Acad Sci U S A       Date:  2001-08-14       Impact factor: 11.205

7.  Axon branching requires interactions between dynamic microtubules and actin filaments.

Authors:  E W Dent; K Kalil
Journal:  J Neurosci       Date:  2001-12-15       Impact factor: 6.167

8.  Dominant-lethal alpha-tubulin mutants defective in microtubule depolymerization in yeast.

Authors:  K R Anders; D Botstein
Journal:  Mol Biol Cell       Date:  2001-12       Impact factor: 4.138

9.  Microtubule treadmilling in vitro investigated by fluorescence speckle and confocal microscopy.

Authors:  S Grego; V Cantillana; E D Salmon
Journal:  Biophys J       Date:  2001-07       Impact factor: 4.033

10.  Dynamic reorientation of cortical microtubules, from transverse to longitudinal, in living plant cells.

Authors:  M Yuan; P J Shaw; R M Warn; C W Lloyd
Journal:  Proc Natl Acad Sci U S A       Date:  1994-06-21       Impact factor: 11.205
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