Literature DB >> 270667

Chemical basis for brain-specific serine transfer RNAs.

H Rogg, P Müller, G Keith, M Staehelin.   

Abstract

Serine tRNA from rat brain can be resolved into six isoaccepting species. Three of these species show the same chromatographic behavior as the seryl tRNAs from other rat organs, whereas the remaining species appear to be specific for brain. The isoacceptor tRNAs were purified to homogeneity by chromatography on benzoylated DEAE-cellulose followed by reversed-phase chromatography. We found that the additional species of serine tRNA in brain differ from their counterparts derived from other rat organs by a lack of a specific guanosine ribose-methylation in the dihydrouridine loop. In addition, when total liver tRNA was compared with total brain tRNA, the same degree of undermethylation with respect to 2'-O-methylguanosine was found as a general phenomenon.

Entities:  

Mesh：

Substances：

Year:  1977        PMID： 270667      PMCID： PMC431915          DOI： 10.1073/pnas.74.10.4243

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  26 in total

1.  Heat-induced stability of tRNA from an extreme thermophile, Thermus thermophilus.

Authors:  K Watanabe; M Shinma; T Oshima; S Nishimura
Journal:  Biochem Biophys Res Commun       Date:  1976-10-04       Impact factor: 3.575

2.  Absence of the sequence G-T-psi-C-G(A)- in several eukaryotic cytoplasmic initiator transfer RNAs.

Authors:  M Simsek; J Ziegenmeyer; J Heckman; U L Rajbhandary
Journal:  Proc Natl Acad Sci U S A       Date:  1973-04       Impact factor: 11.205

3.  Isolation and characterization of serine transfer ribonucleic acids from rat liver.

Authors:  P Müller; W Wehrli; M Staehelin
Journal:  Biochemistry       Date:  1971-05-11       Impact factor: 3.162

4.  On the bias of the distribution of the 2'-O-methylribonucleotide constituents of yeast transfer RNA.

Authors:  S Morisawa; E Chargaff
Journal:  Biochim Biophys Acta       Date:  1968-12-17

5.  On the mRNA induced conformational change of AA-tRNA exposing the T-pse-C-G sequence for binding to the 50S ribosomal subunit.

Authors:  U Schwarz; R Lührmann; H G Gassen
Journal:  Biochem Biophys Res Commun       Date:  1974-02-04       Impact factor: 3.575

6.  Structure of a mammalian serine tRNA.

Authors:  M Staehelin; H Rogg; B C Baguley; T Ginsberg; W Wehrli
Journal:  Nature       Date:  1968-09-28       Impact factor: 49.962

7.  Multiple isoaccepting transfer RNA's in a muouse plasma cell tumor.

Authors:  W K Yang; G D Novelli
Journal:  Proc Natl Acad Sci U S A       Date:  1968-01       Impact factor: 11.205

8.  Transfer RNA specificity in mammalian tissues and codon responses of seryl transfer RNA.

Authors:  D Hatfield; F H Portugal; M Caicuts
Journal:  Cancer Res       Date:  1971-05       Impact factor: 12.701

Review 9.  Transfer RNA and cell differentiation.

Authors:  N Sueoka; T Kano-Sueoka
Journal:  Prog Nucleic Acid Res Mol Biol       Date:  1970

10.  Yeast phenylalanine transfer RNA: atomic coordinates and torsion angles.

Authors:  G J Quigley; N C Seeman; A H Wang; F L Suddath; A Rich
Journal:  Nucleic Acids Res       Date:  1975-12       Impact factor: 16.971
View more
  3 in total

1.  Isolation and characterization of cloned rat DNA fragment carrying tRNA genes.

Authors:  M Lasser-Weiss; N Bawnik; A Rosen; S Sarid; V Daniel
Journal:  Nucleic Acids Res       Date:  1981-11-25       Impact factor: 16.971

2.  Characterization and nucleotide sequence of a chicken gene encoding an opal suppressor tRNA and its flanking DNA segments.

Authors:  D L Hatfield; B S Dudock; F C Eden
Journal:  Proc Natl Acad Sci U S A       Date:  1983-08       Impact factor: 11.205

3.  The yeast Saccharomyces cerevisiae YDL112w ORF encodes the putative 2'-O-ribose methyltransferase catalyzing the formation of Gm18 in tRNAs.

Authors:  J Cavaillé; F Chetouani; J P Bachellerie
Journal:  RNA       Date:  1999-01       Impact factor: 4.942
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.