Nando Ferreira1, Leonard Charles Marais1, Colleen Aldous2. 1. Tumour Sepsis and Reconstruction Unit, Department of Orthopaedic Surgery, Greys Hospital, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, 3201, South Africa. 2. Medical Research Scientist, School of Clinical Medicine, College of Health Sciences, University of KwaZulu-Natal, 4051, South Africa.
Abstract
BACKGROUND: Recent research indicates that atrophic nonunions are biologically active and may heal in the optimal biomechanical environment. METHODS: Thirty-three patients with mobile atrophic and oligotrophic tibial nonunions were treated with circular external fixation and functional rehabilitation. Seven patients required autogenous bone graft procedures. RESULTS: Bony union was achieved after the initial surgery in 31/33 (93.9%) tibias. Two persistent nonunions were successfully treated with repeat circular external fixation without bone graft. This resulted in final bony union in 33/33 (100%) patients. CONCLUSION: Mechanobiological stimulation of tibial nonunions can produce union even if the biological activity appears to be low.
BACKGROUND: Recent research indicates that atrophic nonunions are biologically active and may heal in the optimal biomechanical environment. METHODS: Thirty-three patients with mobile atrophic and oligotrophic tibial nonunions were treated with circular external fixation and functional rehabilitation. Seven patients required autogenous bone graft procedures. RESULTS: Bony union was achieved after the initial surgery in 31/33 (93.9%) tibias. Two persistent nonunions were successfully treated with repeat circular external fixation without bone graft. This resulted in final bony union in 33/33 (100%) patients. CONCLUSION: Mechanobiological stimulation of tibial nonunions can produce union even if the biological activity appears to be low.
Authors: Peter Kloen; Steven B Doty; Eric Gordon; Iván F Rubel; Marie-José Goumans; David L Helfet Journal: J Bone Joint Surg Am Date: 2002-11 Impact factor: 5.284
Authors: Gregory B Lowen; Katherine A Garrett; Stephanie N Moore-Lotridge; Sasidhar Uppuganti; Scott A Guelcher; Jonathan G Schoenecker; Jeffry S Nyman Journal: J Biomech Eng Date: 2022-05-01 Impact factor: 2.097