| Literature DB >> 27011812 |
Brandon J Erickson1, Gregory L Cvetanovich1, Rachel M Frank1, Sanjeev Bhatia1, Charles A Bush-Joseph1, Shane J Nho1, Joshua D Harris2.
Abstract
The goal of this study was to perform a systematic review and meta-analysis of the entire arthroscopic hip preservation literature to answer the question, 'Across the world, are we treating the same patient?' There are significant differences in arthroscopic hip preservation publications, subjects and techniques based on both continent and country published. A systematic review was registered with PROSPERO and performed with PRISMA guidelines using three publicly available databases. Therapeutic clinical outcome investigations reporting arthroscopic hip preservation were eligible for inclusion. All study, subject and surgical technique demographics were analyzed and compared between continents and countries. Statistics were calculated using Student's t-tests, one-way analysis of variance, chi-squared and two-proportion Z-tests. There were 134 studies included in the analysis (10 752 subjects; 11 007 hips; 51% female; mean 37.6 years of age; mean 27.2 months length of follow-up), which had a low Modified Coleman Methodology Score (mean 32.4; poor). North America published the largest number of studies (58%) and the most subjects (55%) and hips (56%). Australia (22%) and Europe (18%) operated on subjects with some amount of osteoarthritis most commonly. North America (2.7%) and Europe (2.0%) operated on subjects with dysplasia or borderline dysplasia most commonly. The Modified Harris Hip Score was the most frequently utilized outcome score (24% of studies). The quantity and quality of arthroscopic hip preservation literature is significantly increasing with time. Several significant differences in study, subject and surgical technique demographics between continents and countries were identified. Deficiencies in use of clinical outcome scores and definitions of treated pathologies preclude complete subject comparisons and serve as an impetus for future study quality improvements.Entities:
Year: 2015 PMID: 27011812 PMCID: PMC4718469 DOI: 10.1093/jhps/hnv013
Source DB: PubMed Journal: J Hip Preserv Surg ISSN: 2054-8397
Fig. 1.PRISMA flowchart.
Demographic data by continent
| North America | South America | Europe | Asia | Australia | |
|---|---|---|---|---|---|
| Number of studies | 78 | 3 | 37 | 11 | 5 |
| Level of evidence | 3.78 ± 0.62 | 3.33 ± 1.15 | 3.89 ± 0.39 | 4 ± 0 | 3.8 ± 0.45 |
| I | 2 | 0 | 0 | 0 | 0 |
| II | 2 | 1 | 1 | 0 | 0 |
| II | 7 | 0 | 2 | 0 | 1 |
| IV | 67 | 2 | 34 | 11 | 4 |
| MCMS | 32.7 ± 10.9 | 36.7 ± 9.3 | 33.0 ± 11.8 | 29.6 ± 10.9 | 30 ± 11.8 |
| Financial conflict of interest | |||||
| Present | 25 | 1 | 5 | 0 | 1 |
| Not present | 39 | 2 | 22 | 7 | 0 |
| Not reported | 14 | 0 | 10 | 4 | 4 |
| Institutional collaboration | |||||
| Single center | 70 | 3 | 35 | 11 | 5 |
| Multi-center | 8 | 0 | 2 | 0 | 0 |
| Number of subjects | 5912 | 367 | 3607 | 195 | 671 |
| Male | 2679 (49.6%) | 187 (51.0%) | 1601 (46.6%) | 97 (49.7%) | 341 (50.8%) |
| Female | 2724 (50.4%) | 180 (49.0%) | 1832 (53.4%) | 98 (50.3%) | 330 (49.2%) |
| Number of hips | 6124 | 367 | 3641 | 197 | 678 |
| Mean age (years) | 34.4 ± 11.1 | 34.7 ± 1.70 | 37.2 ± 13.1 | 41 ± 13.4 | 40.5 ± 17.9 |
| Minimum age (mean across studies) | 23.5 ± 12.9 | 14.7 ± 20.1 | 20.8 ± 12.9 | 27.7 ± 15.6 | 21.3 ± 17.8 |
| Maximum age (mean across studies) | 46.3 ± 18.3 | 61 ± 16.5 | 53.6 ± 19.8 | 52.1 ± 17.5 | 41 ± 33.9 |
| Mean BMI (kg/m2) | 26.9 (17 studies/2289 subjects) | 23.7 (1 study/166 subjects) | 26.8 (5 studies/168 subjects) | 23.2 (1 study/40 subjects) | nr |
| Mean length of follow-up (months) | 27.4 ± 24.4 | 31.8 ± 11.0 | 25.3 ± 22.6 | 30.5 ± 34.7 | 21.0 ± 21.6 |
| Number of studies reporting pre-operative CT scan (number of subjects) | 17 (382) | 0 | 4 (146) | 4 (38) | 2 (104) |
| Number of studies reporting pre-operative MRI scan (number of subjects) | 47 (3625) | 1 (7) | 22 (1191) | 6 (123) | 3 (105) |
CT, computed tomography; nr, not recorded.
aGender not reported in all subjects across studies.
Fig. 2.Number of publications per continent over time.
Fig. 3.(A) Mean MCMS over time for all continents combined. (B) Mean level of evidence over time for all continents combined. Note that lower numerical level of evidence is observed over later publication date, indicative of improved, rather than worse, level of evidence.
Fig. 4.Present or not reported financial conflict of interest over time for all continents combined. COI, conflict of interest.
Demographic data by country
| Country | USA | UK | Switzerland | Germany | Australia |
|---|---|---|---|---|---|
| Number of studies | 72 | 11 | 7 | 7 | 5 |
| Number of subjects (hips) | 5637 (5830) | 2396 (2412) | 307 (318) | 115 (118) | 671 (678) |
| Level of evidence | 3.76 ± 0.64 | 4 | 3.86 ± 0.38 | 4 | 3.8 ± 0.45 |
| I | 2 | 0 | 0 | 0 | 0 |
| II | 2 | 0 | 0 | 0 | 0 |
| III | 7 | 0 | 1 | 0 | 1 |
| IV | 61 | 11 | 6 | 0 | 4 |
| MCMS | 32.7 ± 11.0 | 39.7 ± 7.6 | 32.7 ± 13.0 | 24.3 ± 13.2 | 30 ± 11.8 |
| Financial conflict of interest | |||||
| Present | 23 | 3 | 1 | 0 | 1 |
| Not present | 36 | 7 | 3 | 3 | 0 |
| Not reported | 13 | 1 | 3 | 4 | 4 |
| Institutional Collaboration | |||||
| Single center | 65 | 11 | 7 | 7 | 5 |
| Multi-center | 7 | 0 | 0 | 0 | 0 |
| Number of subjects | |||||
| Malea | 2552 | 1065 | 57 | 36 | 341 |
| Female | 2561 | 1336 | 109 | 44 | 330 |
| Mean age (years) | 34.2 ± 10.8 | 36.7 ± 11.1 | 34.5 ± 11.4 | 36.2 ± 19.0 | 40.5 ± 17.9 |
| Minimum age (mean across studies) | 23.0 ± 12.6 | 21.7 ± 15.1 | 17.3 ± 4.0 | 23.2 ± 16.0 | 21.3 ± 17.8 |
| Maximum age (mean across studies) | 45.3 ± 18.4 | 64.6 ± 11.1 | 50.2 ± 19.7 | 42 ± 18.1 | 50.3 ± 34.7 |
| Mean BMI (kg/m2) | 26.9 | 28.2 | 24.5 | Nr | Nr |
| Mean length of follow-up (months) | 27.8 ± 25.3 | 28.0 ± 20.4 | 16.3 ± 13.4 | 20.6 ± 11.0 | 21.0 ± 21.6 |
Nr, not recorded.
awhen gender was specified in articles.
Definition of CAM impingement and arthritis across continents
| North America | South America | Europe | Asia | Australia | |
|---|---|---|---|---|---|
| Number of studies reporting (subjects) (% of studies reporting a definition) | 14 (949) (18%) | 0 | 7 (337) (9%) | 1 (21) (9%) | 1 (34) (20%) |
| Alpha angle > 45° (oblique) | 1 (36) | 0 | 0 | 0 | |
| Alpha angle > 50° (Dunn 90°) | 3 (67) | 0 | 0 | 0 | |
| Alpha angle > 50° (Cross-table lateral) | 1 (60) | 0 | 0 | 0 | |
| Alpha angle > 50° (Cross-table lateral, frog-leg lateral) | 0 | 0 | 1 (21) | 0 | |
| Alpha angle > 50° (Cross-table lateral, Dunn 45°) | 0 | 1 (110) | 0 | 0 | |
| Alpha angle > 50° (AP, cross-table lateral) | 1 (185) | 0 | 0 | 0 | |
| Alpha angle > 50° (AP, cross-table lateral, Dunn 45°) | 1 (210) | 0 | 0 | 0 | |
| Alpha angle > 55° (MRI, axial oblique) | 0 | 2 (42) | 0 | 0 | |
| Alpha angle > 55° | 1 (9) | 0 | 0 | 0 | |
| Alpha angle > 55° (cross-table lateral) | 2 (126) | 1 (96) | 0 | 0 | |
| Alpha angle > 55° (MRI, axial oblique) | 1 (50) | 0 | 0 | 0 | |
| Alpha angle > 55° (MRI, radial) | 0 | 1 (38) | 0 | 0 | |
| Alpha angle > 55° (Cross-table lateral, or CT scan) | 0 | 0 | 0 | 1 (34) | |
| Alpha angle > 60° (AP, frog-leg lateral, or Dunn 90°) | 1 (58) | 0 | 0 | 0 | |
| Qualitative (Femoral head asphericity) | 2 (148) | 1 (40) | 0 | 0 | |
| Qualitative (Pistol-grip deformity) | 0 | 1 (11) | 0 | 0 | |
| Mean alpha angle (degrees) | 63.8 ± 8.70 | nr | 67.6 ± 9.39 | 65.7 ± 8.5 | nr |
| Number of studies reported (subjects) | 13 (2666) | 5 (256) | 1 (21) | ||
| Proportion of studies reporting (subjects) | 17% (45%) | 14% (7.1%) | 9.1% (11%) | ||
| Number of studies defining hip arthritis (number of hips) | 46 (3099) (59%) | 0 | 24 (2203) (65%) | 7 (180) (64%) | 2 (630) (40%) |
| Via Tonnis grade | 16 (1632) | 12 (435) | 4 (66) | 0 | |
| ≥2 | 15 (1526) | 12 (435) | 4 (66) | ||
| ≥1 | 1 (106) | 0 | 0 | 0 | |
| Via joint space narrowing | 5 (345) | 0 | 1 (21) | ||
| <3 mm | 2 (172) | 0 | 0 | ||
| <2 mm | 2 (172) | 0 | 0 | 1 (560) | |
| ‘Joint space narrowing’ | 1 (1) | 0 | 1 (21) | 0 | |
| Via Outerbridge classification | 3 (291) | 1 (94) | 0 | 1 (70) | |
| Via ‘arthritis’ or ‘osteoarthritis’ | 18 (776) | 9 (1513) | 2 (93) | 0 | |
| Via ‘degenerative changes’ | 3 (19) | 0 | 0 | 0 | |
| Via ‘cartilage delamination’ | 1 (36) | 0 | 0 | ||
| Via Kellgren–Lawrence grade | 0 | 1 (11) | 0 | ||
| Number of hips with arthritis (%) | 312 (10.1%) | nr | 387 (17.6%) | 16 (8.9%) | 137 (21.7%) |
CT, computed tomography; nr, not recorded.
Definition of pincer impingement across continents
| North America | South America | Europe | Asia | Australia | |
|---|---|---|---|---|---|
| Number of studies reporting (subjects) (% of studies reporting a definition) | 16 (949) (21%) | 0 | 8 (471) (22%) | 1 (21) (9%) | 0 |
| Crossover sign | 9 (535) | 7 (353) | 1 (21) | ||
| Coxa profunda | 7 (522) | 4 (182) | 1 (21) | ||
| Protrusio acetabulae | 7 (430) | 4 (182) | 0 | ||
| Acetabular retroversion | 3 (305) | 1 (118) | 1 (21) | ||
| LCEA > 40° | 2 (150) | 0 | 1 (21) | ||
| ACEA > 35° | 1 (60) | 0 | 0 | ||
| Tönnis angle < 0° | 1 (60) | 0 | 0 | ||
| Ischial spine sign | 1 (36) | 1 (101) | 0 | ||
| Posterior wall sign | 0 | 1 (11) | 0 | ||
| Mean lateral center edge angle (degrees) | 31.2 ± 10.8 | nr | 31.7 ± 6.71 | nr | nr |
| Number of studies reported (subjects) | 12 (1747) | 3 (215) | |||
| Proportion of studies reporting (subjects) | 15% (30%) | 8.1% (6.0%) | |||
| Mean anterior center edge angle (degrees) | 28.5 ± 3.54 | nr | nr | nr | nr |
| Number of studies reported (subjects) | 2 (110) | ||||
| Proportion of studies reporting (subjects) | 2.6% (1.9%) | ||||
| Mean Tönnis angle | 7.0° | nr | 12.8° | nr | nr |
| Number of studies reported (subjects) | 4 (26) | 1 (86) | |||
| Proportion of studies reporting (subjects) | 5.1% (0.4%) | 2.7% (2.4%) | |||
| Number of studies assessing AIIS impingement (subspine impingement) | 4 (228) | nr | nr | nr | nr |
ACEA, anterior center edge angle; AIIS, anterior inferior iliac spine; LCEA, lateral center edge angle; nr, not recorded.
aRetroversion defined as anteversion less than 14 degrees.
Definition of hip dysplasia across continents
| North America | South America | Europe | Asia | Australia | |
|---|---|---|---|---|---|
| Number of studies defining hip dysplasia (number of hips) | 16 (1,048) (21%) | 0 | 5 (473) (14%) | 0 | 0 |
| Via LCEA < 25° | 4 (176) | 3 (276) | |||
| Via LCEA < 20° | 7 (457) | 1 (111) | |||
| Via ACEA < 20° | 2 (61) | ||||
| Via Tönnis angle > 10° | 2 (110) | ||||
| Via acetabular index < 20° | 1 (36) | ||||
| Via “dysplasia” | 2 (251) | ||||
| Via femoral head coverage (CT/MRI) | 1 (1) | ||||
| Via hypertrophic labrum (MR, arthroscopy) | 1 (1) | ||||
| Via anterior or posterior femoral head surface area <10% | 1 (36) | 1 (86) | |||
| Via Type I (incongruent) or II (short arc) | 13 (320) | 8 (366) | 1 (7) | 1 (1) | |
| Not defined, but reported the number of subjects with dysplasia | |||||
| Number of studies defining borderline hip dysplasia (number of hips) | 0 | 0 | 0 | ||
| Via LCEA 20°–25° | 4 (252) | 1 (111) | |||
| Via LCEA 18°–25° | 1 (22) | 0 | |||
| Via ACEA 20°–25° | 1 (106) | 0 | |||
| Via Sharp’s angle > 40° | 1 (106) | 0 | |||
| Number of subjects with hip dysplasia | 82 | nr | 63 | 7 | 0 |
| Number of subjects with borderline hip dysplasia | 78 | nr | 10 | 0 | 1 |
| Number of studies that excluded dysplastic hips from investigation (proportion) | 10 (13%) | nr | 5 (14%) | 0 | 1 (20%) |
ACEA, anterior center edge angle; LCEA, lateral center edge angle; CT, computed tomography; nr, not recorded.
Indications for surgery across continents
| Indications for surgery, number of studies (number of subjects) | North America | South America | Europe | Asia | Australia |
|---|---|---|---|---|---|
| FAI | 26 (1971) | 1 (194) | 8 (712) | 1 (73) | |
| Labral tear | 18 (1912) | 1 (194) | 2 (51) | 2 (22) | 1 (70) |
| Arthritis | 1 (60) | 1 (22) | |||
| Dysplasia | 2 (25) | ||||
| Coxa saltans | 3 (59) | 1 (7) | 1 (15) | ||
| Pain | 19 (2190) | 1 (166) | 18 (2654) | 1 (40) | 3 (602) |
| Trauma (femoral head fracture) | 1 (2) | 1 (11) | |||
| Trauma (hip dislocation) | 3 (40) | 1 (8) | |||
| Loose bodies | 5 (5) | 1 (4) | 3 (22) | ||
| Revision hip arthroscopy | 1 (60) | ||||
| Ligamentum teres tear | 1 (4) | ||||
| Pigmented villonodular synovitis | 1 (13) | 1 (1) | |||
| Synovial chondromatosis | 2 (122) | 1 (24) | |||
| Abductor tendon tear | 1 (11) | ||||
| Septic arthritis | 1 (6) | ||||
| Symptomatic paralabral cyst | 1 (2) | ||||
| Calcified rectus femoris tendon | 1 (3) | ||||
| Chondral defects | 2 (55) |
Most utilized outcome scores across continents
| Outcome score | North America | South America | Europe | Asia | Australia |
|---|---|---|---|---|---|
| NAHS | 42.0 ± 17.8 (6; 440; 7.2%) | 48.9 ± 4.96 (9; 422; 11.6%) | 67.1 ± 7.0 (2; 601; 89%) | ||
| HOS | |||||
| Activities of daily living | 70.0 ± 11.7 (8; 398; 6.5%) | 52.8 (1; 4; 0.1%) | |||
| Sports | 44.1 ± 6.34 (9; 463; 7.6%) | nr | |||
| Modified HHS | 61.6 ± 6.51 (23; 2519; 41%) | 56.1 (1; 7; 1.9%) | 58.2 ± 13.7 (7; 1006; 28%) | 46.1 (1; 40; 20%) | 68.0 ± 7.1 (2; 601; 89%) |
| HHS | 50.4 ± 13.2 (3; 47; 24%) | ||||
| Hip disability and Osteoarthritis Outcome Score | |||||
| Pain | 46.4 (1; 94; 2.6%) | ||||
| Symptoms | 44.2 (1; 94; 2.6%) | ||||
| Activities of daily living | 51.1 (1; 94; 2.6%) | ||||
| Sports and recreation | 30.7 (1; 94; 2.6%) | ||||
| Quality of life | 39.6 (1; 94; 2.6%) | ||||
| WOMAC | 36.6 ± 7.8 (3; 180; 2.9%) | 47.2 ± 20.4 (3; 172; 4.7% | 65 (1; 2; 1.0%) | ||
| Tegner activity score | 7.6 (1; 15; 0.4%) | ||||
| SF-12 | |||||
| PCS | 46.6 ± 18.0 (3; 1503; 25%) | ||||
| MCS | 53 (1; 1264; 21%) | ||||
| iHOT-12 | |||||
| iHOT-33 | |||||
| SF-36 | |||||
| EQ-5-QoL | |||||
| Marx activity score | |||||
nr, not recorded.
Blank cells indicate that no clinical outcome score was utilized. In parentheses: (number of studies reporting this variable; number of subjects with this variable measured; proportion of subjects within overall geographic area with that variable measured).