Literature DB >> 26998299

Breast cancer following polyacrylamide hydrogel injection for breast augmentation: A case report.

Gang Chen1, Yujia Wang2, Jin-Long Huang1.   

Abstract

Polyacrylamide hydrogel (PAAG) has been used for several years as an injectable implant for augmentation mammoplasty in China. Although patients who received PAAG injections experienced a number of complications, breast cancer following PAAG injection has been reported only in two cases. In this report, we present a case of breast cancer following PAAG injection for breast augmentation. Our study demonstrated that PAAG injection may increase the risk of breast cancer development. Early-stage breast cancer detection is difficult, since the breast is covered with the indurated injected gel. Thus, PAAG injection for augmentation mammoplasty may negatively affect breast cancer diagnosis and prognosis.

Entities:  

Keywords:  augmentation mammoplasty; breast cancer; magnetic resonance imaging; mammography; polyacrylamide hydrogel injection; ultrasonic

Year:  2016        PMID: 26998299      PMCID: PMC4774455          DOI: 10.3892/mco.2016.731

Source DB:  PubMed          Journal:  Mol Clin Oncol        ISSN: 2049-9450


  19 in total

1.  Cytotoxicity and altered c-myc gene expression by medical polyacrylamide hydrogel.

Authors:  T F Xi; C X Fan; X M Feng; Z Y Wan; C R Wang; L L Chou
Journal:  J Biomed Mater Res A       Date:  2006-08       Impact factor: 4.396

2.  Our strategy in complication management of augmentation mammaplasty with polyacrylamide hydrogel injection in 235 patients.

Authors:  Sheng-Kang Luo; Gunang-Ping Chen; Zhong-Shen Sun; Ning-Xin Cheng
Journal:  J Plast Reconstr Aesthet Surg       Date:  2010-11-11       Impact factor: 2.740

Review 3.  Amended final report on the safety assessment of polyacrylamide and acrylamide residues in cosmetics.

Authors: 
Journal:  Int J Toxicol       Date:  2005       Impact factor: 2.032

4.  Breast cancer detection using magnetic resonance imaging in breasts injected with liquid silicone.

Authors:  H L Peng; C C Wu; W M Choi; M S Hui; T N Lu; L K Chen
Journal:  Plast Reconstr Surg       Date:  1999-12       Impact factor: 4.730

5.  Breast implants and cancer: causation, delayed detection, and survival.

Authors:  S J Hoshaw; P J Klein; B D Clark; R R Cook; L L Perkins
Journal:  Plast Reconstr Surg       Date:  2001-05       Impact factor: 4.730

6.  Augmentation mammaplasty and breast cancer: a 5-year update of the Los Angeles study.

Authors:  D M Deapen; G S Brody
Journal:  Plast Reconstr Surg       Date:  1992-04       Impact factor: 4.730

7.  Factors affecting mammographic visualization of the breast after augmentation mammaplasty.

Authors:  N Handel; M J Silverstein; P Gamagami; J A Jensen; A Collins
Journal:  JAMA       Date:  1992-10-14       Impact factor: 56.272

Review 8.  Breast cancer detection and survival among women with cosmetic breast implants: systematic review and meta-analysis of observational studies.

Authors:  Eric Lavigne; Eric J Holowaty; Sai Yi Pan; Paul J Villeneuve; Kenneth C Johnson; Dean A Fergusson; Howard Morrison; Jacques Brisson
Journal:  BMJ       Date:  2013-04-29

9.  How should we investigate breast implant rupture?

Authors:  Phoebe M Hold; Shabana Alam; William J Pilbrow; Judith F Kelly; Elizabeth M Everitt; Sanjiv K Dhital; Ali Juma
Journal:  Breast J       Date:  2012 May-Jun       Impact factor: 2.431

10.  Imaging of breast implants-a pictorial review.

Authors:  Sergi Juanpere; Elsa Perez; Oscar Huc; Naiara Motos; Josep Pont; Salvador Pedraza
Journal:  Insights Imaging       Date:  2011-08-07
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  2 in total

1.  Immediate prosthetic breast reconstruction after removal of the polyacrylamide hydrogel (PAAG) through a small areolar incision assisted with an endoscope.

Authors:  Dandan Guan; Qiuping Mo; Yajuan Zheng
Journal:  BMC Surg       Date:  2022-09-07       Impact factor: 2.030

2.  Clinicopathological Analysis of 90 Cases of Polyacrylamide Hydrogel Injection for Breast Augmentation Including 2 Cases Followed by Breast Cancer.

Authors:  Ying Yang; Shumo Li; Jia He; Xian Zhao; Wei Chen; Xiaoming Dai; Liu Liu
Journal:  Breast Care (Basel)       Date:  2019-05-29       Impact factor: 2.860

  2 in total

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