Literature DB >> 26955397

Nanomedicines for Endothelial Disorders.

Bomy Lee Chung1, Michael J Toth2, Nazila Kamaly3, Yoshitaka J Sei2, Jacob Becraft4, Willem J M Mulder5, Zahi A Fayad5, Omid C Farokhzad6, YongTae Kim2, Robert Langer7.   

Abstract

The endothelium lines the internal surfaces of blood and lymphatic vessels and has a critical role in maintaining homeostasis. Endothelial dysfunction is involved in the pathology of many diseases and conditions, including disorders such as diabetes, cardiovascular diseases, and cancer. Given this common etiology in a range of diseases, medicines targeting an impaired endothelium can strengthen the arsenal of therapeutics. Nanomedicine - the application of nanotechnology to healthcare - presents novel opportunities and potential for the treatment of diseases associated with an impaired endothelium. This review discusses therapies currently available for the treatment of these disorders and highlights the application of nanomedicine for the therapy of these major disease complications.

Entities:  

Keywords:  atherosclerosis; cancer; diabetes; endothelial disorder; endothelium; nanomedicine; permeability

Year:  2015        PMID： 26955397      PMCID： PMC4778260          DOI： 10.1016/j.nantod.2015.11.009

Source DB:  PubMed          Journal:  Nano Today        ISSN： 1748-0132            Impact factor:   20.722


  223 in total

Review 1.  Apolipoprotein E recycling: implications for dyslipidemia and atherosclerosis.

Authors:  Joerg Heeren; Ulrike Beisiegel; Thomas Grewal
Journal:  Arterioscler Thromb Vasc Biol       Date:  2005-12-22       Impact factor: 8.311

2.  Nanoparticles enhance therapeutic efficiency by selectively increased local drug dose in experimental colitis in rats.

Authors:  Alf Lamprecht; Hiromitsu Yamamoto; Hirofumi Takeuchi; Yoshiaki Kawashima
Journal:  J Pharmacol Exp Ther       Date:  2005-06-24       Impact factor: 4.030

3.  Efficient siRNA delivery using water soluble lipopolymer for anti-angiogenic gene therapy.

Authors:  Won Jong Kim; Chien-Wen Chang; Minhyung Lee; Sung Wan Kim
Journal:  J Control Release       Date:  2007-01-09       Impact factor: 9.776

4.  Synergistic cytotoxicity of irinotecan and cisplatin in dual-drug targeted polymeric nanoparticles.

Authors:  Pedro M Valencia; Eric M Pridgen; Brian Perea; Suresh Gadde; Christopher Sweeney; Philip W Kantoff; Neil H Bander; Stephen J Lippard; Robert Langer; Rohit Karnik; Omid C Farokhzad
Journal:  Nanomedicine (Lond)       Date:  2012-10-17       Impact factor: 5.307

Review 5.  Delivery of nano-objects to functional sub-domains of healthy and failing cardiac myocytes.

Authors:  Valeriy Lukyanenko
Journal:  Nanomedicine (Lond)       Date:  2007-12       Impact factor: 5.307

Review 6.  Endothelium-dependent vasodilation and oxidative stress in chronic renal failure: impact on cardiovascular disease.

Authors:  Margus Annuk; Mihkel Zilmer; Bengt Fellström
Journal:  Kidney Int Suppl       Date:  2003-05       Impact factor: 10.545

7.  Effect of verapamil, trandolapril and their combination on vascular function and structure in essential hypertensive patients.

Authors:  D Versari; A Virdis; L Ghiadoni; E Daghini; E Duranti; S Masi; A Magagna; S Taddei
Journal:  Atherosclerosis       Date:  2008-12-03       Impact factor: 5.162

8.  MMP-9-positive neutrophil infiltration is associated to blood-brain barrier breakdown and basal lamina type IV collagen degradation during hemorrhagic transformation after human ischemic stroke.

Authors:  Anna Rosell; Eloy Cuadrado; Arantxa Ortega-Aznar; Mar Hernández-Guillamon; Eng H Lo; Joan Montaner
Journal:  Stroke       Date:  2008-03-06       Impact factor: 7.914

9.  Molecular imaging of angiogenesis in nascent Vx-2 rabbit tumors using a novel alpha(nu)beta3-targeted nanoparticle and 1.5 tesla magnetic resonance imaging.

Authors:  Patrick M Winter; Shelton D Caruthers; Andrea Kassner; Thomas D Harris; Lori K Chinen; John S Allen; Elizabeth K Lacy; Huiying Zhang; J David Robertson; Samuel A Wickline; Gregory M Lanza
Journal:  Cancer Res       Date:  2003-09-15       Impact factor: 12.701

Review 10.  The use of microfluidics in hemostasis: clinical diagnostics and biomimetic models of vascular injury.

Authors:  Keith B Neeves; Abimbola A Onasoga; Adam R Wufsus
Journal:  Curr Opin Hematol       Date:  2013-09       Impact factor: 3.284
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  8 in total

Review 1.  Nanomedicines for dysfunctional macrophage-associated diseases.

Authors:  Hongliang He; Shobha Ghosh; Hu Yang
Journal:  J Control Release       Date:  2017-01-03       Impact factor: 9.776

2.  In Vivo Sentinel Lymph Node Detection with Indocyanine Green in Colorectal Cancer.

Authors:  Daniel Staniloaie; Constantin Budin; Alexandru Ilco; Danut Vasile; Amalia Loredana Calinoiu; Adina Rusu; George Iancu; Tarek Ammar; Cristian Florin Georgescu; Maria-Daniela Tanasescu; Alexandru Minca; Dragos Eugen Georgescu
Journal:  Maedica (Bucur)       Date:  2022-06

3.  Robust manufacturing of lipid-polymer nanoparticles through feedback control of parallelized swirling microvortices.

Authors:  Michael J Toth; Taeyoung Kim; YongTae Kim
Journal:  Lab Chip       Date:  2017-08-08       Impact factor: 6.799

Review 4.  Nanomaterials for Antiangiogenic Therapies for Cancer: A Promising Tool for Personalized Medicine.

Authors:  Hashem O Alsaab; Alanoud S Al-Hibs; Rami Alzhrani; Khawlah K Alrabighi; Aljawharah Alqathama; Akram Alwithenani; Atiah H Almalki; Yusuf S Althobaiti
Journal:  Int J Mol Sci       Date:  2021-02-05       Impact factor: 5.923

Review 5.  Cancer Stem Cells and the Tumor Microenvironment: Targeting the Critical Crosstalk through Nanocarrier Systems.

Authors:  Aadya Nayak; Neerada Meenakshi Warrier; Praveen Kumar
Journal:  Stem Cell Rev Rep       Date:  2022-07-25       Impact factor: 6.692

6.  Detection of frequency-dependent endothelial response to oscillatory shear stress using a microfluidic transcellular monitor.

Authors:  Yoshitaka J Sei; Song Ih Ahn; Theodore Virtue; Taeyoung Kim; YongTae Kim
Journal:  Sci Rep       Date:  2017-08-30       Impact factor: 4.379

Review 7.  Advances in nanomedicine for cancer starvation therapy.

Authors:  Shuangjiang Yu; Zhaowei Chen; Xuan Zeng; Xuesi Chen; Zhen Gu
Journal:  Theranostics       Date:  2019-10-17       Impact factor: 11.556

Review 8.  Nanomedicine therapies modulating Macrophage Dysfunction: a potential strategy to attenuate Cytokine Storms in severe infections.

Authors:  Jingping Liu; Meihua Wan; Christopher J Lyon; Tony Y Hu
Journal:  Theranostics       Date:  2020-07-25       Impact factor: 11.556
  8 in total

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