Literature DB >> 28057522

Nanomedicines for dysfunctional macrophage-associated diseases.

Hongliang He1, Shobha Ghosh2, Hu Yang3.   

Abstract

Macrophages play vital functions in host inflammatory reaction, tissue repair, homeostasis and immunity. Dysfunctional macrophages have significant pathophysiological impacts on diseases such as cancer, inflammatory diseases (rheumatoid arthritis and inflammatory bowel disease), metabolic diseases (atherosclerosis, diabetes and obesity) and major infections like human immunodeficiency virus infection. In view of this common etiology in these diseases, targeting the recruitment, activation and regulation of dysfunctional macrophages represents a promising therapeutic strategy. With the advancement of nanotechnology, development of nanomedicines to efficiently target dysfunctional macrophages can strengthen the effectiveness of therapeutics and improve clinical outcomes. This review discusses the specific roles of dysfunctional macrophages in various diseases and summarizes the latest advances in nanomedicine-based therapeutics and theranostics for treating diseases associated with dysfunctional macrophages.
Copyright © 2017 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Cell receptor; Drug delivery; Gene therapy; In vivo; Macrophage phenotype; Tissue macrophages

Mesh：

Year:  2017        PMID： 28057522      PMCID： PMC5360184          DOI： 10.1016/j.jconrel.2016.12.032

Source DB:  PubMed          Journal:  J Control Release        ISSN： 0168-3659            Impact factor:   9.776


  211 in total

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Journal:  ACS Nano       Date:  2013-09-18       Impact factor: 15.881

Review 2.  Targeting inflammation in the treatment of type 2 diabetes: time to start.

Authors:  Marc Y Donath
Journal:  Nat Rev Drug Discov       Date:  2014-05-23       Impact factor: 84.694

3.  Molecular imaging of folate receptor β-positive macrophages during acute lung inflammation.

Authors:  Wei Han; Rinat Zaynagetdinov; Fiona E Yull; Vasiliy V Polosukhin; Linda A Gleaves; Harikrishna Tanjore; Lisa R Young; Todd E Peterson; H Charles Manning; Lawrence S Prince; Timothy S Blackwell
Journal:  Am J Respir Cell Mol Biol       Date:  2015-07       Impact factor: 6.914

Review 4.  Nanoparticle-based theranostic agents.

Authors:  Jin Xie; Seulki Lee; Xiaoyuan Chen
Journal:  Adv Drug Deliv Rev       Date:  2010-08-04       Impact factor: 15.470

5.  Bioconjugated Manganese Dioxide Nanoparticles Enhance Chemotherapy Response by Priming Tumor-Associated Macrophages toward M1-like Phenotype and Attenuating Tumor Hypoxia.

Authors:  Manli Song; Ting Liu; Changrong Shi; Xiangzhong Zhang; Xiaoyuan Chen
Journal:  ACS Nano       Date:  2015-12-14       Impact factor: 15.881

6.  Morphologically virus-like fullerenol nanoparticles act as the dual-functional nanoadjuvant for HIV-1 vaccine.

Authors:  Ligeng Xu; Ye Liu; Zhiyun Chen; Wei Li; Ying Liu; Liming Wang; Liying Ma; Yiming Shao; Yuliang Zhao; Chunying Chen
Journal:  Adv Mater       Date:  2013-08-21       Impact factor: 30.849

Review 7.  Anti-tumour strategies aiming to target tumour-associated macrophages.

Authors:  Xiaoqiang Tang; Chunfen Mo; Yongsheng Wang; Dandan Wei; Hengyi Xiao
Journal:  Immunology       Date:  2013-02       Impact factor: 7.397

8.  Detection of atherosclerotic lesions and intimal macrophages using CD36-targeted nanovesicles.

Authors:  Shufang Nie; Jia Zhang; Raul Martinez-Zaguilan; Souad Sennoune; Md Nazir Hossen; Alice H Lichtenstein; Jun Cao; Gary E Meyerrose; Ralph Paone; Suthipong Soontrapa; Zhaoyang Fan; Shu Wang
Journal:  J Control Release       Date:  2015-10-09       Impact factor: 9.776

9.  Targeting colon cancer cell NF-κB promotes an anti-tumour M1-like macrophage phenotype and inhibits peritoneal metastasis.

Authors:  A E Ryan; A Colleran; A O'Gorman; L O'Flynn; J Pindjacova; P Lohan; G O'Malley; M Nosov; C Mureau; L J Egan
Journal:  Oncogene       Date:  2014-04-07       Impact factor: 9.867

10.  Tumor-Associated Macrophage-Mediated Targeted Therapy of Triple-Negative Breast Cancer.

Authors:  Mengmeng Niu; Solange Valdes; Youssef W Naguib; Stephen D Hursting; Zhengrong Cui
Journal:  Mol Pharm       Date:  2016-04-26       Impact factor: 4.939
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  17 in total

1.  Development of mannose functionalized dendrimeric nanoparticles for targeted delivery to macrophages: use of this platform to modulate atherosclerosis.

Authors:  Hongliang He; Quan Yuan; Jinghua Bie; Ryan L Wallace; Paul J Yannie; Jing Wang; Michael G Lancina; Olga Yu Zolotarskaya; William Korzun; Hu Yang; Shobha Ghosh
Journal:  Transl Res       Date:  2017-11-21       Impact factor: 7.012

Review 2.  Recent progress of macrophage vesicle-based drug delivery systems.

Authors:  Wen-Jie Xu; Jia-Xin Cai; Yong-Jiang Li; Jun-Yong Wu; Daxiong Xiang
Journal:  Drug Deliv Transl Res       Date:  2022-01-04       Impact factor: 5.671

3.  Leutusome: A Biomimetic Nanoplatform Integrating Plasma Membrane Components of Leukocytes and Tumor Cells for Remarkably Enhanced Solid Tumor Homing.

Authors:  Hongliang He; Chunqing Guo; Jing Wang; William J Korzun; Xiang-Yang Wang; Shobha Ghosh; Hu Yang
Journal:  Nano Lett       Date:  2018-09-17       Impact factor: 11.189

Review 4.  Mineralocorticoid Receptor Signaling as a Therapeutic Target for Renal and Cardiac Fibrosis.

Authors:  Greg H Tesch; Morag J Young
Journal:  Front Pharmacol       Date:  2017-05-29       Impact factor: 5.810

5.  Photoactive Liposomal Formulation of PVP-Conjugated Chlorin e6 for Photodynamic Reduction of Atherosclerotic Plaque.

Authors:  Wojciech Kałas; Edyta Wysokińska; Magdalena Przybyło; Marek Langner; Agnieszka Ulatowska-Jarża; Dariusz Biały; Magdalena Wawrzyńska; Ewa Zioło; Wojciech Gil; Anna M Trzeciak; Halina Podbielska; Marta Kopaczyńska
Journal:  Int J Mol Sci       Date:  2019-08-07       Impact factor: 5.923

6.  Luteolin Induces Apoptosis and Autophagy in Mouse Macrophage ANA-1 Cells via the Bcl-2 Pathway.

Authors:  Yuexia Liao; Yang Xu; Mengyao Cao; Yuanyuan Huan; Lei Zhu; Ye Jiang; Weigan Shen; Guoqiang Zhu
Journal:  J Immunol Res       Date:  2018-08-30       Impact factor: 4.818

Review 7.  Multivalent nanosystems: targeting monocytes/macrophages.

Authors:  Rémy Poupot; Cécile Goursat; Séverine Fruchon
Journal:  Int J Nanomedicine       Date:  2018-09-19

Review 8.  Targeting of Hepatic Macrophages by Therapeutic Nanoparticles.

Authors:  Clara I Colino; José M Lanao; Carmen Gutierrez-Millan
Journal:  Front Immunol       Date:  2020-03-04       Impact factor: 7.561

9.  In vivo liposomal delivery of PPARα/γ dual agonist tesaglitazar in a model of obesity enriches macrophage targeting and limits liver and kidney drug effects.

Authors:  Victoria Osinski; Dustin K Bauknight; Siva Sai Krishna Dasa; Matthew J Harms; Tobias Kroon; Melissa A Marshall; James C Garmey; Anh T Nguyen; Julia Hartman; Aditi Upadhye; Prasad Srikakulapu; Andrea Zhou; Gavin O'Mahony; Alexander L Klibanov; Kimberly A Kelly; Jeremie Boucher; Coleen A McNamara
Journal:  Theranostics       Date:  2020-01-01       Impact factor: 11.556

10.  Targeting of immunosuppressive myeloid cells from glioblastoma patients by modulation of size and surface charge of lipid nanocapsules.

Authors:  Laura Pinton; Sara Magri; Elena Masetto; Marina Vettore; Ilaria Schibuola; Vincenzo Ingangi; Ilaria Marigo; Kevin Matha; Jean-Pierre Benoit; Alessandro Della Puppa; Vincenzo Bronte; Giovanna Lollo; Susanna Mandruzzato
Journal:  J Nanobiotechnology       Date:  2020-02-17       Impact factor: 10.435
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