Literature DB >> 26944478

Retroviral insertional mutagenesis identifies the del(5q) genes, CXXC5, TIFAB and ETF1, as well as the Wnt pathway, as potential targets in del(5q) myeloid neoplasms.

Angela Stoddart1, Zhijian Qian2, Anthony A Fernald3, Rachel J Bergerson4, Jianghong Wang3, Theodore Karrison5, John Anastasi6, Elizabeth T Bartom7, Aaron L Sarver4, Megan E McNerney8, David A Largaespada4, Michelle M Le Beau9.   

Abstract

Entities:  

Keywords:  Wnt pathway; del(5q); insertional mutagenesis; myeloid neoplasms; retroviral

Mesh：

Substances：

Year:  2016        PMID： 26944478      PMCID： PMC5013937          DOI： 10.3324/haematol.2015.139527

Source DB:  PubMed          Journal:  Haematologica        ISSN： 0390-6078            Impact factor:   9.941


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  15 in total

1.  Haploinsufficient loss of multiple 5q genes may fine-tune Wnt signaling in del(5q) therapy-related myeloid neoplasms.

Authors:  Angela Stoddart; Joy Nakitandwe; Shann-Ching Chen; James R Downing; Michelle M Le Beau
Journal:  Blood       Date:  2015-11-13       Impact factor: 22.113

2.  Downregulation but lack of promoter hypermethylation or somatic mutations of the potential tumor suppressor CXXC5 in MDS and AML with deletion 5q.

Authors:  Marianne B Treppendahl; Lars Möllgård; Eva Hellström-Lindberg; Paul Cloos; Kirsten Grønbaek
Journal:  Eur J Haematol       Date:  2013-01-20       Impact factor: 2.997

3.  GREAT improves functional interpretation of cis-regulatory regions.

Authors:  Cory Y McLean; Dave Bristor; Michael Hiller; Shoa L Clarke; Bruce T Schaar; Craig B Lowe; Aaron M Wenger; Gill Bejerano
Journal:  Nat Biotechnol       Date:  2010-05-02       Impact factor: 54.908

4.  Revised international prognostic scoring system for myelodysplastic syndromes.

Authors:  Peter L Greenberg; Heinz Tuechler; Julie Schanz; Guillermo Sanz; Guillermo Garcia-Manero; Francesc Solé; John M Bennett; David Bowen; Pierre Fenaux; Francois Dreyfus; Hagop Kantarjian; Andrea Kuendgen; Alessandro Levis; Luca Malcovati; Mario Cazzola; Jaroslav Cermak; Christa Fonatsch; Michelle M Le Beau; Marilyn L Slovak; Otto Krieger; Michael Luebbert; Jaroslaw Maciejewski; Silvia M M Magalhaes; Yasushi Miyazaki; Michael Pfeilstöcker; Mikkael Sekeres; Wolfgang R Sperr; Reinhard Stauder; Sudhir Tauro; Peter Valent; Teresa Vallespi; Arjan A van de Loosdrecht; Ulrich Germing; Detlef Haase
Journal:  Blood       Date:  2012-06-27       Impact factor: 22.113

5.  Targeted re-sequencing analysis of 25 genes commonly mutated in myeloid disorders in del(5q) myelodysplastic syndromes.

Authors:  Marta Fernandez-Mercado; Adam Burns; Andrea Pellagatti; Aristoteles Giagounidis; Ulrich Germing; Xabier Agirre; Felipe Prosper; Carlo Aul; Sally Killick; James S Wainscoat; Anna Schuh; Jacqueline Boultwood
Journal:  Haematologica       Date:  2013-07-05       Impact factor: 9.941

6.  Evaluation of ETF1/eRF1, mapping to 5q31, as a candidate myeloid tumor suppressor gene.

Authors:  Christèle Dubourg; Bertrand Toutain; Catherine Hélias; Catherine Henry; Michel Lessard; Jean Yves Le Gall; André Le Treut; Lucienne Guenet
Journal:  Cancer Genet Cytogenet       Date:  2002-04-01

7.  A Moloney murine leukemia virus-based retrovirus with 4070A long terminal repeat sequences induces a high incidence of myeloid as well as lymphoid neoplasms.

Authors:  Linda Wolff; Richard Koller; Xinrong Hu; Miriam R Anver
Journal:  J Virol       Date:  2003-04       Impact factor: 5.103

8.  Haploinsufficiency of EGR1, a candidate gene in the del(5q), leads to the development of myeloid disorders.

Authors:  John M Joslin; Anthony A Fernald; Thelma R Tennant; Elizabeth M Davis; Scott C Kogan; John Anastasi; John D Crispino; Michelle M Le Beau
Journal:  Blood       Date:  2007-04-09       Impact factor: 22.113

9.  The transcription factor EGR1 controls both the proliferation and localization of hematopoietic stem cells.

Authors:  Irene M Min; Giorgio Pietramaggiori; Francis S Kim; Emmanuelle Passegué; Kristen E Stevenson; Amy J Wagers
Journal:  Cell Stem Cell       Date:  2008-04-10       Impact factor: 24.633

10.  Downregulation of the Wnt inhibitor CXXC5 predicts a better prognosis in acute myeloid leukemia.

Authors:  Andrea Kühnl; Peter J M Valk; Mathijs A Sanders; Adam Ivey; Robert K Hills; Ken I Mills; Rosemary E Gale; Martin F Kaiser; Richard Dillon; Melanie Joannides; Amanda Gilkes; Torsten Haferlach; Susanne Schnittger; Estelle Duprez; David C Linch; Ruud Delwel; Bob Löwenberg; Claudia D Baldus; Ellen Solomon; Alan K Burnett; David Grimwade
Journal:  Blood       Date:  2015-03-24       Impact factor: 22.113
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  11 in total

1.  Epistasis between TIFAB and miR-146a: neighboring genes in del(5q) myelodysplastic syndrome.

Authors:  M E Varney; K Choi; L Bolanos; S Christie; J Fang; H L Grimes; J P Maciejewski; J-I Inoue; D T Starczynowski
Journal:  Leukemia       Date:  2016-10-03       Impact factor: 11.528

2.  Inhibition of WNT signaling in the bone marrow niche prevents the development of MDS in the Apcdel/+ MDS mouse model.

Authors:  Angela Stoddart; Jianghong Wang; Chunmei Hu; Anthony A Fernald; Elizabeth M Davis; Jason X Cheng; Michelle M Le Beau
Journal:  Blood       Date:  2017-03-27       Impact factor: 22.113

Review 3.  Chronic immune response dysregulation in MDS pathogenesis.

Authors:  Laura Barreyro; Timothy M Chlon; Daniel T Starczynowski
Journal:  Blood       Date:  2018-08-13       Impact factor: 22.113

4.  TIFAB Regulates USP15-Mediated p53 Signaling during Stressed and Malignant Hematopoiesis.

Authors:  Madeline Niederkorn; Kathleen Hueneman; Kwangmin Choi; Melinda E Varney; Laurel Romano; Mario A Pujato; Kenneth D Greis; Jun-Ichiro Inoue; Ruhikanta Meetei; Daniel T Starczynowski
Journal:  Cell Rep       Date:  2020-02-25       Impact factor: 9.423

5.  Overexpression of CXXC5 is a strong poor prognostic factor in ER+ breast cancer.

Authors:  Lei Fang; Yu Wang; Yang Gao; Xuejun Chen
Journal:  Oncol Lett       Date:  2018-05-07       Impact factor: 2.967

6.  Cytotoxic Therapy-Induced Effects on Both Hematopoietic and Marrow Stromal Cells Promotes Therapy-Related Myeloid Neoplasms.

Authors:  Angela Stoddart; Jianghong Wang; Anthony A Fernald; Elizabeth M Davis; Camille R Johnson; Chunmei Hu; Jason X Cheng; Megan E McNerney; Michelle M Le Beau
Journal:  Blood Cancer Discov       Date:  2020-07

7.  Computational analysis and verification of molecular genetic targets for glioblastoma.

Authors:  Liang Xue; Haibing Liu; Yehuang Chen; Liangfeng Wei; Jingfang Hong
Journal:  Biosci Rep       Date:  2020-06-26       Impact factor: 3.840

8.  Comparative proteomic analysis of different stages of breast cancer tissues using ultra high performance liquid chromatography tandem mass spectrometer.

Authors:  Abdullah Saleh Al-Wajeeh; Salizawati Muhamad Salhimi; Majed Ahmed Al-Mansoub; Imran Abdul Khalid; Thomas Michael Harvey; Aishah Latiff; Mohd Nazri Ismail
Journal:  PLoS One       Date:  2020-01-16       Impact factor: 3.240

9.  Prognostic value of immune-related genes in laryngeal squamous cell carcinoma.

Authors:  Weixing Liu; Chunyi Zhang; Xin Gong; Wenjing Liao; Jun Xu; Xiaowen Zhang
Journal:  Transl Cancer Res       Date:  2020-10       Impact factor: 1.241

10.  The epigenetic regulator RINF (CXXC5) maintains <i>SMAD7</i> expression in human immature erythroid cells and sustains red blood cells expansion.

Authors:  Audrey Astori; Gabriel Matherat; Isabelle Munoz; Emilie-Fleur Gautier; Didier Surdez; Yaël Zermati; Frédérique Verdier; Sakina Zaidi; Vincent Feuillet; Amir Kadi; Evelyne Lauret; Olivier Delattre; Carine Lefèvre; Michaela Fontenay; Evelyne Ségal-Bendirdjian; Isabelle Dusanter-Fourt; Didier Bouscary; Olivier Hermine; Patrick Mayeux; Frédéric Pendino
Journal:  Haematologica       Date:  2022-01-01       Impact factor: 9.941
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