Literature DB >> 23190153

Downregulation but lack of promoter hypermethylation or somatic mutations of the potential tumor suppressor CXXC5 in MDS and AML with deletion 5q.

Marianne B Treppendahl, Lars Möllgård, Eva Hellström-Lindberg, Paul Cloos, Kirsten Grønbaek.   

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Year:  2013        PMID： 23190153     DOI： 10.1111/ejh.12045

Source DB:  PubMed          Journal:  Eur J Haematol        ISSN： 0902-4441            Impact factor:   2.997


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  12 in total

1.  Haploinsufficient loss of multiple 5q genes may fine-tune Wnt signaling in del(5q) therapy-related myeloid neoplasms.

Authors:  Angela Stoddart; Joy Nakitandwe; Shann-Ching Chen; James R Downing; Michelle M Le Beau
Journal:  Blood       Date:  2015-11-13       Impact factor: 22.113

2.  CXXC5 regulates differentiation of C2C12 myoblasts into myocytes.

Authors:  Guangming Li; Xiangli Ye; Xiyang Peng; Yun Deng; Wuzhou Yuan; Yongqing Li; Xiaoyang Mo; Xijun Wang; Yongqi Wan; Xianchu Liu; Tingfang Chen; Zhigang Jiang; Xiongwei Fan; Xiushan Wu; Yuequn Wang
Journal:  J Muscle Res Cell Motil       Date:  2014-11-30       Impact factor: 2.698

3.  Retroviral insertional mutagenesis identifies the del(5q) genes, CXXC5, TIFAB and ETF1, as well as the Wnt pathway, as potential targets in del(5q) myeloid neoplasms.

Authors:  Angela Stoddart; Zhijian Qian; Anthony A Fernald; Rachel J Bergerson; Jianghong Wang; Theodore Karrison; John Anastasi; Elizabeth T Bartom; Aaron L Sarver; Megan E McNerney; David A Largaespada; Michelle M Le Beau
Journal:  Haematologica       Date:  2016-03-04       Impact factor: 9.941

4.  DNMT3A Haploinsufficiency Transforms FLT3ITD Myeloproliferative Disease into a Rapid, Spontaneous, and Fully Penetrant Acute Myeloid Leukemia.

Authors:  Sara E Meyer; Tingting Qin; David E Muench; Kohei Masuda; Meenakshi Venkatasubramanian; Emily Orr; Lauren Suarez; Steven D Gore; Ruud Delwel; Elisabeth Paietta; Martin S Tallman; Hugo Fernandez; Ari Melnick; Michelle M Le Beau; Scott Kogan; Nathan Salomonis; Maria E Figueroa; H Leighton Grimes
Journal:  Cancer Discov       Date:  2016-03-25       Impact factor: 39.397

5.  Downregulation of the Wnt inhibitor CXXC5 predicts a better prognosis in acute myeloid leukemia.

Authors:  Andrea Kühnl; Peter J M Valk; Mathijs A Sanders; Adam Ivey; Robert K Hills; Ken I Mills; Rosemary E Gale; Martin F Kaiser; Richard Dillon; Melanie Joannides; Amanda Gilkes; Torsten Haferlach; Susanne Schnittger; Estelle Duprez; David C Linch; Ruud Delwel; Bob Löwenberg; Claudia D Baldus; Ellen Solomon; Alan K Burnett; David Grimwade
Journal:  Blood       Date:  2015-03-24       Impact factor: 22.113

6.  Estradiol-Estrogen Receptor α Mediates the Expression of the CXXC5 Gene through the Estrogen Response Element-Dependent Signaling Pathway.

Authors:  Pelin Yaşar; Gamze Ayaz; Mesut Muyan
Journal:  Sci Rep       Date:  2016-11-25       Impact factor: 4.379

7.  Epigenetic regulator CXXC5 recruits DNA demethylase Tet2 to regulate TLR7/9-elicited IFN response in pDCs.

Authors:  Shixin Ma; Xiaoling Wan; Zihou Deng; Lei Shi; Congfang Hao; Zhenyuan Zhou; Chun Zhou; Yiyuan Fang; Jinghua Liu; Jing Yang; Xia Chen; Tiantian Li; Aiping Zang; Shigang Yin; Bin Li; Joel Plumas; Laurence Chaperot; Xiaoming Zhang; Guoliang Xu; Lubin Jiang; Nan Shen; Sidong Xiong; Xiaoming Gao; Yan Zhang; Hui Xiao
Journal:  J Exp Med       Date:  2017-04-17       Impact factor: 14.307

Review 8.  CXXC5: A novel regulator and coordinator of TGF-β, BMP and Wnt signaling.

Authors:  Xiangyang Xiong; Shuo Tu; Jianbin Wang; Shiwen Luo; Xiaohua Yan
Journal:  J Cell Mol Med       Date:  2018-11-27       Impact factor: 5.310

9.  CXXC5 (retinoid-inducible nuclear factor, RINF) is a potential therapeutic target in high-risk human acute myeloid leukemia.

Authors:  Audrey Astori; Hanne Fredly; Thomas Aquinas Aloysius; Lars Bullinger; Véronique Mansat-De Mas; Pierre de la Grange; François Delhommeau; Karen Marie Hagen; Christian Récher; Isabelle Dusanter-Fourt; Stian Knappskog; Johan Richard Lillehaug; Frédéric Pendino; Øystein Bruserud
Journal:  Oncotarget       Date:  2013-09

10.  CXXC5 as an unmethylated CpG dinucleotide binding protein contributes to estrogen-mediated cellular proliferation.

Authors:  Gamze Ayaz; Negin Razizadeh; Pelin Yaşar; Gizem Kars; Deniz Cansen Kahraman; Özge Saatci; Özgür Şahin; Rengül Çetin-Atalay; Mesut Muyan
Journal:  Sci Rep       Date:  2020-04-06       Impact factor: 4.379
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