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Literature DB >> 26927813

Novel universal influenza virus vaccine approaches.

Abstract

Seasonal influenza virus vaccines have to be re-formulated and re-administered on an annual basis due to antigenic drift of the influenza virus surface glycoproteins. In addition, seasonal vaccines show limited efficacy against novel pandemic influenza virus strains, and producing tailored vaccines for these strains in a timely manner is challenging. Several novel broadly protective vaccine candidates targeting the conserved stalk domain of the viral hemagglutinin have been developed. Here we review these novel constructs and discuss several important findings and considerations regarding the protective efficacy of stalk-based vaccines.

Entities: Chemical

Mesh：

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Year: 2016 PMID： 26927813 PMCID： PMC4902764 DOI： 10.1016/j.coviro.2016.02.002

Source DB: PubMed Journal: Curr Opin Virol ISSN： 1879-6257 Impact factor: 7.090

87 in total

1. The Quest for a Universal Flu Vaccine: Headless HA 2.0.

Authors: Florian Krammer
Journal: Cell Host Microbe Date: 2015-10-14 Impact factor: 21.023

2. A virus-like particle that elicits cross-reactive antibodies to the conserved stem of influenza virus hemagglutinin.

Authors: Anette Schneemann; Jeffrey A Speir; Gene S Tan; Reza Khayat; Damian C Ekiert; Yumiko Matsuoka; Ian A Wilson
Journal: J Virol Date: 2012-08-15 Impact factor: 5.103

3. Serum immunoglobulin levels in healthy children and adults.

Authors: J W Stoop; B J Zegers; P C Sander; R E Ballieux
Journal: Clin Exp Immunol Date: 1969-01 Impact factor: 4.330

4. A common solution to group 2 influenza virus neutralization.

Authors: Robert H E Friesen; Peter S Lee; Esther J M Stoop; Ryan M B Hoffman; Damian C Ekiert; Gira Bhabha; Wenli Yu; Jarek Juraszek; Wouter Koudstaal; Mandy Jongeneelen; Hans J W M Korse; Carla Ophorst; Els C M Brinkman-van der Linden; Mark Throsby; Mark J Kwakkenbos; Arjen Q Bakker; Tim Beaumont; Hergen Spits; Ted Kwaks; Ronald Vogels; Andrew B Ward; Jaap Goudsmit; Ian A Wilson
Journal: Proc Natl Acad Sci U S A Date: 2013-12-11 Impact factor: 11.205

5. Pandemic H1N1 influenza vaccine induces a recall response in humans that favors broadly cross-reactive memory B cells.

Authors: Gui-Mei Li; Christopher Chiu; Jens Wrammert; Megan McCausland; Sarah F Andrews; Nai-Ying Zheng; Jane-Hwei Lee; Min Huang; Xinyan Qu; Srilatha Edupuganti; Mark Mulligan; Suman R Das; Jonathan W Yewdell; Aneesh K Mehta; Patrick C Wilson; Rafi Ahmed
Journal: Proc Natl Acad Sci U S A Date: 2012-05-21 Impact factor: 11.205

6. Complement-dependent lysis of influenza a virus-infected cells by broadly cross-reactive human monoclonal antibodies.

Authors: Masanori Terajima; John Cruz; Mary Dawn T Co; Jane-Hwei Lee; Kaval Kaur; Jens Wrammert; Patrick C Wilson; Francis A Ennis
Journal: J Virol Date: 2011-10-12 Impact factor: 5.103

7. A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza A hemagglutinins.

Authors: Davide Corti; Jarrod Voss; Steven J Gamblin; Giosiana Codoni; Annalisa Macagno; David Jarrossay; Sebastien G Vachieri; Debora Pinna; Andrea Minola; Fabrizia Vanzetta; Chiara Silacci; Blanca M Fernandez-Rodriguez; Gloria Agatic; Siro Bianchi; Isabella Giacchetto-Sasselli; Lesley Calder; Federica Sallusto; Patrick Collins; Lesley F Haire; Nigel Temperton; Johannes P M Langedijk; John J Skehel; Antonio Lanzavecchia
Journal: Science Date: 2011-07-28 Impact factor: 47.728

8. H3N2 influenza virus infection induces broadly reactive hemagglutinin stalk antibodies in humans and mice.

Authors: Irina Margine; Rong Hai; Randy A Albrecht; Gerlinde Obermoser; A Carson Harrod; Jacques Banchereau; Karolina Palucka; Adolfo García-Sastre; Peter Palese; John J Treanor; Florian Krammer
Journal: J Virol Date: 2013-02-13 Impact factor: 5.103

9. Neutralizing antibodies against previously encountered influenza virus strains increase over time: a longitudinal analysis.

Authors: Matthew S Miller; Thomas J Gardner; Florian Krammer; Lauren C Aguado; Domenico Tortorella; Christopher F Basler; Peter Palese
Journal: Sci Transl Med Date: 2013-08-14 Impact factor: 17.956

Review 10. Influenza virus hemagglutinin stalk-based antibodies and vaccines.

Authors: Florian Krammer; Peter Palese
Journal: Curr Opin Virol Date: 2013-08-24 Impact factor: 7.090

47 in total

Review 1. Inactivated influenza virus vaccines: the future of TIV and QIV.

Authors: Michael Schotsaert; Adolfo García-Sastre
Journal: Curr Opin Virol Date: 2017-05-12 Impact factor: 7.090

2. Animal Cell Expression Systems.

Authors: M Butler; U Reichl
Journal: Adv Biochem Eng Biotechnol Date: 2021 Impact factor: 2.635

3. Impact of aging and HIV infection on serologic response to seasonal influenza vaccination.

Authors: Suresh Pallikkuth; Lesley R De Armas; Rajendra Pahwa; Stefano Rinaldi; Varghese K George; Celeste M Sanchez; Li Pan; Gordon Dickinson; Allan Rodriguez; Margaret Fischl; Maria Alcaide; Savita Pahwa
Journal: AIDS Date: 2018-06-01 Impact factor: 4.177

4. Characterization of humoral and cellular immune features of gamma-irradiated influenza vaccine.

Authors: Fengjia Chen; Ho Seong Seo; Hyun Jung Ji; Eunji Yang; Jung Ah Choi; Jae Seung Yang; Manki Song; Seung Hyun Han; Sangyong Lim; Jae Hyang Lim; Ki Bum Ahn
Journal: Hum Vaccin Immunother Date: 2020-07-09 Impact factor: 3.452

5. One Step Forward in the Road Toward a Universal Influenza Vaccine.

Authors: Octavio Ramilo; Rosa Rodriguez-Fernandez; Asuncion Mejias
Journal: J Infect Dis Date: 2017-12-27 Impact factor: 5.226

6. Protein Vaccination Directs the CD4⁺ T Cell Response toward Shared Protective Epitopes That Can Be Recalled after Influenza Virus Infection.

Authors: Ajitanuj Rattan; Katherine A Richards; Zackery A G Knowlden; Andrea J Sant
Journal: J Virol Date: 2019-09-30 Impact factor: 5.103