Literature DB >> 26898812

Ammonium tetrathiomolybdate as a water-soluble and slow-release hydrogen sulfide donor.

Shi Xu1, Chun-Tao Yang2, Fu-Hui Meng2, Armando Pacheco1, Li Chen2, Ming Xian3.   

Abstract

Ammonium tetrathiomolybdate (TTM) was found to be a slow hydrogen sulfide (H2S) releasing agent. Its H2S generation capability in aqueous solutions was confirmed by UV-vis and fluorescence assays. TTM also showed H2S-like cytoprotective effects in hydrogen peroxide (H2O2)-induced oxidative damage in HaCaT cells.
Copyright © 2016 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Ammonium tetrathiomolybdate; Donor; Hydrogen sulfide; Oxidative damage

Mesh：

Substances：

Year:  2016        PMID： 26898812      PMCID： PMC4775341          DOI： 10.1016/j.bmcl.2016.02.005

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  17 in total

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