Literature DB >> 26893827

Epigenetics in systemic lupus erythematosus.

Gong Xiao1, Xiaoxia Zuo1.   

Abstract

Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease, with mechanisms that remain to be elucidated. Previous studies have proposed that genes and environments are required for lupus to develop and flare. It has been found that epigenetics have a significant influence on SLE. The present review will concentrate on epigenetics in SLE. There are a number of studies reporting that autoreactive T cells and B cells in patients with SLE have evidence of altered patterns of DNA methylation, modifications of histones and microRNA (miRNA). Long noncoding RNAs (lncRNAs) are another type of noncoding RNAs, which have an important role in epigenetics. lncRNAs may possibly become a new hotspot in SLE.

Entities:  

Keywords:  epigenetics; lupus

Year:  2015        PMID： 26893827      PMCID： PMC4734248          DOI： 10.3892/br.2015.556

Source DB:  PubMed          Journal:  Biomed Rep        ISSN： 2049-9434


  63 in total

1.  Visiting "noncodarnia".

Authors:  Jeffrey M Perkel
Journal:  Biotechniques       Date:  2013-06       Impact factor: 1.993

2.  Studies on peroxynitrite-modified H1 histone: implications in systemic lupus erythematosus.

Authors:  M Asad Khan; Kiran Dixit; Zarina Arif; Khursheed Alam
Journal:  Biochimie       Date:  2013-10-07       Impact factor: 4.079

3.  Evidence for impaired T cell DNA methylation in systemic lupus erythematosus and rheumatoid arthritis.

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Journal:  Arthritis Rheum       Date:  1990-11

Review 4.  Updating on the pathogenesis of systemic lupus erythematosus.

Authors:  R Gualtierotti; M Biggioggero; A E Penatti; P L Meroni
Journal:  Autoimmun Rev       Date:  2010-09-21       Impact factor: 9.754

5.  Genome-wide DNA methylation patterns in CD4+ T cells from patients with systemic lupus erythematosus.

Authors:  Matlock A Jeffries; Mikhail Dozmorov; Yuhong Tang; Joan T Merrill; Jonathan D Wren; Amr H Sawalha
Journal:  Epigenetics       Date:  2011-05-01       Impact factor: 4.528

6.  Protein phosphatase 2A enables expression of interleukin 17 (IL-17) through chromatin remodeling.

Authors:  Sokratis A Apostolidis; Thomas Rauen; Christian M Hedrich; George C Tsokos; José C Crispín
Journal:  J Biol Chem       Date:  2013-08-05       Impact factor: 5.157

Review 7.  Genetic susceptibility to SLE: new insights from fine mapping and genome-wide association studies.

Authors:  Isaac T W Harley; Kenneth M Kaufman; Carl D Langefeld; John B Harley; Jennifer A Kelly
Journal:  Nat Rev Genet       Date:  2009-05       Impact factor: 53.242

8.  MicroRNA-146A contributes to abnormal activation of the type I interferon pathway in human lupus by targeting the key signaling proteins.

Authors:  Yuanjia Tang; Xiaobing Luo; Huijuan Cui; Xuming Ni; Min Yuan; Yanzhi Guo; Xinfang Huang; Haibo Zhou; Niek de Vries; Paul Peter Tak; Shunle Chen; Nan Shen
Journal:  Arthritis Rheum       Date:  2009-04

9.  4-Hydroxy-2-nonenal modified histone-H2A: a possible antigenic stimulus for systemic lupus erythematosus autoantibodies.

Authors:  Abdullateef A Alzolibani; Ahmad A Al Robaee; Hani A Al-Shobaili; Zafar Rasheed
Journal:  Cell Immunol       Date:  2013-08-02       Impact factor: 4.868

Review 10.  Environmental factors, toxicants and systemic lupus erythematosus.

Authors:  Anselm Mak; Sen Hee Tay
Journal:  Int J Mol Sci       Date:  2014-09-11       Impact factor: 5.923
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  8 in total

Review 1.  Exploring the etiopathogenesis of systemic lupus erythematosus: a genetic perspective.

Authors:  Ali Javinani; Amir Ashraf-Ganjouei; Saeed Aslani; Ahmadreza Jamshidi; Mahdi Mahmoudi
Journal:  Immunogenetics       Date:  2019-01-22       Impact factor: 2.846

Review 2.  DNA methylation in systemic lupus erythematosus.

Authors:  Christian M Hedrich; Katrin Mäbert; Thomas Rauen; George C Tsokos
Journal:  Epigenomics       Date:  2016-11-25       Impact factor: 4.778

3.  Selective HDAC6 inhibition decreases early stage of lupus nephritis by down-regulating both innate and adaptive immune responses.

Authors:  J Ren; X Liao; M D Vieson; M Chen; R Scott; J Kazmierczak; X M Luo; C M Reilly
Journal:  Clin Exp Immunol       Date:  2017-10-16       Impact factor: 4.330

4.  The role of microRNA-31 and microRNA-21 as regulatory biomarkers in the activation of T lymphocytes of Egyptian lupus patients.

Authors:  Khalda Sayed Amr; Faten S Bayoumi; Fatema T Elgengehy; Sanaa O Abdallah; Hanan H Ahmed; Eman Eissa
Journal:  Rheumatol Int       Date:  2016-08-10       Impact factor: 2.631

Review 5.  RNA Methylation in Systemic Lupus Erythematosus.

Authors:  Xinyi Lv; Xiaomin Liu; Ming Zhao; Haijing Wu; Wuiguang Zhang; Qianjin Lu; Xiangmei Chen
Journal:  Front Cell Dev Biol       Date:  2021-07-07

6.  Drug-induced Rowell syndrome, a rare and difficult to manage disease: A case report.

Authors:  Daciana Elena Brănișteanu; Simona Laura Ianoşi; Andreea Dimitriu; Gabriela Stoleriu; Alexandru Oanţǎ; Daniel Constantin Brănișteanu
Journal:  Exp Ther Med       Date:  2017-11-23       Impact factor: 2.447

7.  Ezh2-mediated epigenetic modification is required for allogeneic T cell-induced lupus disease.

Authors:  Yuxuan Zhen; Roger D Smith; Fred D Finkelman; Wen-Hai Shao
Journal:  Arthritis Res Ther       Date:  2020-06-05       Impact factor: 5.156

8.  Personalized therapy design for systemic lupus erythematosus based on the analysis of protein-protein interaction networks.

Authors:  Elizabeth J Brant; Edward A Rietman; Giannoula Lakka Klement; Marco Cavaglia; Jack A Tuszynski
Journal:  PLoS One       Date:  2020-03-19       Impact factor: 3.240
  8 in total

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