Literature DB >> 26885129

Prognostic value of three pro-nuclei (3PN) incidence in elective single blastocyst-stage embryo transfer.

Mingzhao Li1, Wanqiu Zhao1, Wei Li1, Xiaoli Zhao1, Juanzi Shi1.   

Abstract

OBJECTIVES: To investigate whether 3PN incidence could lead to a worse pregnancy outcome of elective single blastocyst stage embryo transfer (eSBET).
METHODS: This study included 706 eSBET cycles from January 2013 to March 2015. The patients were divided into two groups as follows: group 1 included 286 patients with no 3PN zygotes and group 2 included 420 patients with 3PN zygotes. MAIN OUTCOME MEASURE: female age, endometrial thickness, infertility duration, type of infertility, main etiology of infertility, clinical pregnancy and abortion rate.
RESULTS: We observed that there was no significant difference in female age, endometrial thickness, infertility duration and abortion rate between two groups. It's worth noting that the clinical pregnancy rate in 3PN > 0% group was significantly lower than 3PN = 0 group (P = 0.021).
CONCLUSIONS: 3PN incidence might make anegative effect on pregnancy outcomes in elective single blastocyst stage embryo transfer.

Entities:  

Keywords:  3PN; pregnancy; single blastocyst

Year:  2015        PMID: 26885129      PMCID: PMC4723974     

Source DB:  PubMed          Journal:  Int J Clin Exp Med        ISSN: 1940-5901


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