Literature DB >> 26880168

Gene expression profiling and DNA methylation analyses of CTCs.

Evi S Lianidou1.   

Abstract

A variety of molecular assays have been developed for CTCs detection and molecular characterization. Molecular assays are based on the nucleic acid analysis in CTCs and are based on total RNA isolation and subsequent mRNA quantification of specific genes, or isolation of genomic DNA that can be for DNA methylation studies and mutation analysis. This review is mainly focused on gene expression and methylation studies in CTCs in various types of cancer.
Copyright © 2016 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.

Entities:  

Keywords:  CTCs; Circulating Tumor Cells; Gene expression; Methylation specific PCR; Molecular assays; Molecular characterization; Multiplex RT-PCR; Quantitative PCR (qPCR); RT-qPCR; Reverse transcription PCR

Mesh：

Year:  2016        PMID： 26880168      PMCID： PMC5528973          DOI： 10.1016/j.molonc.2016.01.011

Source DB:  PubMed          Journal:  Mol Oncol        ISSN： 1574-7891            Impact factor:   6.603


  108 in total

Review 1.  Cysteine cathepsins: multifunctional enzymes in cancer.

Authors:  Mona Mostafa Mohamed; Bonnie F Sloane
Journal:  Nat Rev Cancer       Date:  2006-10       Impact factor: 60.716

2.  Predictive and prognostic value of peripheral blood cytokeratin-19 mRNA-positive cells detected by real-time polymerase chain reaction in node-negative breast cancer patients.

Authors:  Nikos Xenidis; Maria Perraki; Maria Kafousi; Stella Apostolaki; Irene Bolonaki; Aliki Stathopoulou; Kostas Kalbakis; Nikos Androulakis; Charalambos Kouroussis; Thanos Pallis; Charalambos Christophylakis; Katerina Argyraki; Evi S Lianidou; Stathis Stathopoulos; Vassilis Georgoulias; Dimitris Mavroudis
Journal:  J Clin Oncol       Date:  2006-06-12       Impact factor: 44.544

3.  Molecular profiling and predictive value of circulating tumor cells in patients with metastatic breast cancer: an option for monitoring response to breast cancer related therapies.

Authors:  Mitra Tewes; Bahriye Aktas; Anja Welt; Siemke Mueller; Siegfried Hauch; Rainer Kimmig; Sabine Kasimir-Bauer
Journal:  Breast Cancer Res Treat       Date:  2008-08-05       Impact factor: 4.872

4.  Circulating tumor cells, disease progression, and survival in metastatic breast cancer.

Authors:  Massimo Cristofanilli; G Thomas Budd; Matthew J Ellis; Alison Stopeck; Jeri Matera; M Craig Miller; James M Reuben; Gerald V Doyle; W Jeffrey Allard; Leon W M M Terstappen; Daniel F Hayes
Journal:  N Engl J Med       Date:  2004-08-19       Impact factor: 91.245

5.  Detection and characterization of invasive circulating tumor cells derived from men with metastatic castration-resistant prostate cancer.

Authors:  Terence W Friedlander; Vy T Ngo; Huan Dong; Gayatri Premasekharan; Vivian Weinberg; Shaun Doty; Qiang Zhao; Elizabeth G Gilbert; Charles J Ryan; Wen-Tien Chen; Pamela L Paris
Journal:  Int J Cancer       Date:  2014-01-02       Impact factor: 7.396

6.  Cancer. Circulating tumor cells.

Authors:  Vicki Plaks; Charlotte D Koopman; Zena Werb
Journal:  Science       Date:  2013-09-13       Impact factor: 47.728

7.  Methylation of cystatin M promoter is associated with unfavorable prognosis in operable breast cancer.

Authors:  Magdalini Kioulafa; Ioanna Balkouranidou; Georgia Sotiropoulou; Loukas Kaklamanis; Dimitris Mavroudis; Vassilis Georgoulias; Evi S Lianidou
Journal:  Int J Cancer       Date:  2009-12-15       Impact factor: 7.396

8.  Prognostic significance of CTCs and CSCs of tumor drainage vein blood in Dukes' stage B and C colorectal cancer patients.

Authors:  Ryu Shimada; Hisae Iinuma; Takuya Akahane; Atsushi Horiuchi; Toshiaki Watanabe
Journal:  Oncol Rep       Date:  2012-01-19       Impact factor: 3.906

9.  Detection of Circulating Tumour Cells from Blood of Breast Cancer Patients via RT-qPCR.

Authors:  Ulrich Andergassen; Alexandra C Kölbl; Stefan Hutter; Klaus Friese; Udo Jeschke
Journal:  Cancers (Basel)       Date:  2013-09-25       Impact factor: 6.639

10.  Complex tumor genomes inferred from single circulating tumor cells by array-CGH and next-generation sequencing.

Authors:  Ellen Heitzer; Martina Auer; Christin Gasch; Martin Pichler; Peter Ulz; Eva Maria Hoffmann; Sigurd Lax; Julie Waldispuehl-Geigl; Oliver Mauermann; Carolin Lackner; Gerald Höfler; Florian Eisner; Heinz Sill; Hellmut Samonigg; Klaus Pantel; Sabine Riethdorf; Thomas Bauernhofer; Jochen B Geigl; Michael R Speicher
Journal:  Cancer Res       Date:  2013-03-07       Impact factor: 12.701
View more
  19 in total

Review 1.  Gene expression profiling and DNA methylation analyses of CTCs.

Authors:  Evi S Lianidou
Journal:  Mol Oncol       Date:  2016-02-05       Impact factor: 6.603

Review 2.  The promise of circulating tumor cells for precision cancer therapy.

Authors:  William L Hwang; Katie L Hwang; David T Miyamoto
Journal:  Biomark Med       Date:  2016-12-07       Impact factor: 2.851

3.  A fluorescent immunosensor for determination and imaging of circulating tumor cells based on a bifunctional DNA nanomachine.

Authors:  Ye Zhang; Shihua Luo; Bo Situ; Xinyi Ye; Yifang Huang; Bo Li; Xiujuan Jiang; Xueping Chen; Lei Zheng; Xiaohui Yan
Journal:  Mikrochim Acta       Date:  2020-04-04       Impact factor: 5.833

Review 4.  Pathologists and liquid biopsies: to be or not to be?

Authors:  Paul Hofman; Helmut H Popper
Journal:  Virchows Arch       Date:  2016-08-23       Impact factor: 4.064

Review 5.  Challenges and unanswered questions for the next decade of circulating tumour cell research in lung cancer.

Authors:  Sumitra Mohan; Francesca Chemi; Ged Brady
Journal:  Transl Lung Cancer Res       Date:  2017-08

Review 6.  [Current progress in research of circulating tumor cells].

Authors:  Qian-Wen Zhao; Bo Situ; Lei Zheng
Journal:  Nan Fang Yi Ke Da Xue Xue Bao       Date:  2017-10-20

7.  The role of circulating tumor cells in metastatic breast cancer: prognostic and predictive value.

Authors:  Abeer A Bahnassy; Magdy M Saber; Mohamed G Mahmoud; Mona S Abdellateif; Mohamed Abd El-Mooti Samra; Rafaat M Abd El-Fatah; Abdel-Rahman N Zekri; Salem E Salem
Journal:  Mol Biol Rep       Date:  2018-09-18       Impact factor: 2.316

8.  Analysis of DNA methylation in single circulating tumor cells.

Authors:  C F Pixberg; K Raba; F Müller; B Behrens; E Honisch; D Niederacher; H Neubauer; T Fehm; W Goering; W A Schulz; P Flohr; G Boysen; M Lambros; J S De Bono; W T Knoefel; C Sproll; N H Stoecklein; R P L Neves
Journal:  Oncogene       Date:  2017-01-09       Impact factor: 9.867

9.  Molecular characterization of circulating tumor cells from patients with metastatic breast cancer reflects evolutionary changes in gene expression under the pressure of systemic therapy.

Authors:  Kristina E Aaltonen; Vendula Novosadová; Pär-Ola Bendahl; Cecilia Graffman; Anna-Maria Larsson; Lisa Rydén
Journal:  Oncotarget       Date:  2017-07-11

10.  Efficient leukocyte depletion by a novel microfluidic platform enables the molecular detection and characterization of circulating tumor cells.

Authors:  Eva Obermayr; Elisabeth Maritschnegg; Christiane Agreiter; Nina Pecha; Paul Speiser; Samir Helmy-Bader; Sabine Danzinger; Michael Krainer; Christian Singer; Robert Zeillinger
Journal:  Oncotarget       Date:  2017-11-28
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.