| Literature DB >> 26879309 |
Tove Lekva1,2, Errol R Norwitz3,4, Pål Aukrust5,6,7, Thor Ueland8,9.
Abstract
With increasing rates of obesity and new diagnostic criteria for gestational diabetes mellitus (GDM), the overall prevalence of GDM is increasing worldwide. Women with GDM have an increased risk of maternal and fetal complications during pregnancy as well as long-term risks including higher prevalence of type 2 diabetes mellitus and cardiovascular disease. In recent years, the role of immune activation and inflammation in the pathogenesis of GDM has gained increasing attention. This monograph explores the current state of the literature as regards the expression of markers of inflammation in the maternal circulation, placenta, and adipose tissue of women with GDM.Entities:
Keywords: Adipose tissue; GDM; Placenta; Systemic inflammation
Mesh:
Year: 2016 PMID: 26879309 DOI: 10.1007/s11892-016-0715-9
Source DB: PubMed Journal: Curr Diab Rep ISSN: 1534-4827 Impact factor: 4.810