You-Fan Peng1, Xiang-Hui Su2, Man-Man Han1, Xiang-Yun Zhu1, Ling Li1. 1. Department of Endocrinology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing 210009, China. 2. Department of Endocrinology, The First Affiliated Hospital of the Medical College, Shihezi University, Shihezi 832003, China.
Abstract
BACKGROUND: The aim of our study is to explore the relationship between serum uric acid (UA) and high-risk pregnancy (HRP) in advanced pregnant women. METHODS: The study included 226 advanced pregnant women (≥35 years), and the HRP score were assessed according to China HRP score standards. RESULTS: All data were separated into the three groups according to HRP score, we observed significant increases of serum UA concentrations between the three groups (207.51±42.45; 226.65±45.42 and 228.27±49.70 µmol/L, P=0.017). Notably, serum UA concentrations were found to be positive correlated with HRP score (r=0.165, P=0.013) in advanced pregnant women. Serum UA was independent correlated with HRP score (beta =0.164, P=0.009) in multiple linear regression analysis. CONCLUSIONS: We conclude that serum UA is correlated with HRP score, and increased serum UA levels may herald HRP in advanced pregnant women.
BACKGROUND: The aim of our study is to explore the relationship between serum uric acid (UA) and high-risk pregnancy (HRP) in advanced pregnant women. METHODS: The study included 226 advanced pregnant women (≥35 years), and the HRP score were assessed according to China HRP score standards. RESULTS: All data were separated into the three groups according to HRP score, we observed significant increases of serum UA concentrations between the three groups (207.51±42.45; 226.65±45.42 and 228.27±49.70 µmol/L, P=0.017). Notably, serum UA concentrations were found to be positive correlated with HRP score (r=0.165, P=0.013) in advanced pregnant women. Serum UA was independent correlated with HRP score (beta =0.164, P=0.009) in multiple linear regression analysis. CONCLUSIONS: We conclude that serum UA is correlated with HRP score, and increased serum UA levels may herald HRP in advanced pregnant women.
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