| Literature DB >> 26873398 |
Xiaogang Su1, Chalani S Wijayasinghe2, Juanjuan Fan3, Ying Zhang4,5.
Abstract
We propose a new sparse estimation method for Cox (1972) proportional hazards models by optimizing an approximated information criterion. The main idea involves approximation of the ℓ0 norm with a continuous or smooth unit dent function. The proposed method bridges the best subset selection and regularization by borrowing strength from both. It mimics the best subset selection using a penalized likelihood approach yet with no need of a tuning parameter. We further reformulate the problem with a reparameterization step so that it reduces to one unconstrained nonconvex yet smooth programming problem, which can be solved efficiently as in computing the maximum partial likelihood estimator (MPLE). Furthermore, the reparameterization tactic yields an additional advantage in terms of circumventing postselection inference. The oracle property of the proposed method is established. Both simulated experiments and empirical examples are provided for assessment and illustration.Entities:
Keywords: AIC; BIC; Cox proportional hazards model; Regularization; Sparse estimation; Variable selection
Mesh:
Year: 2016 PMID: 26873398 PMCID: PMC4982849 DOI: 10.1111/biom.12484
Source DB: PubMed Journal: Biometrics ISSN: 0006-341X Impact factor: 2.571