Jaedon P Avey1, Vanessa Y Hiratsuka1, Julie A Beans1, Susan Brown Trinidad2, Rachel F Tyndale3, Renee F Robinson1. 1. Research Department, Southcentral Foundation, 4105 Tudor Centre Drive, Anchorage, AK 99508, USA. 2. Department of Bioethics & Humanities, University of Washington, Box 357120, Seattle, WA 98195-7120, USA. 3. Campbell Family Mental Health Research Institute, Centre for Addiction & Mental Health, Departments of Psychiatry, and Pharmacology & Toxicology, University of Toronto, Medical Science Building Room 4326, 1 King's College Circle, Toronto, ON, M5S 1A8, Canada.
Abstract
AIM: Describe patients,' providers' and healthcare system leaders' perceptions of pharmacogenetic research to guide tobacco cessation treatment in an American Indian/Alaska Native primary care setting. MATERIALS & METHODS: This qualitative study used semistructured interviews with 20 American Indian/Alaska Native current or former tobacco users, 12 healthcare providers and nine healthcare system leaders. RESULTS: Participants supported pharmacogenetic research to guide tobacco cessation treatment provided that a community-based participatory research approach be employed, research closely coordinate with existing tobacco cessation services and access to pharmacogenetic test results be restricted to providers involved in tobacco cessation. CONCLUSION: Despite a history of mistrust toward genetic research in tribal communities, participants expressed willingness to support pharmacogenetic research to guide tobacco cessation treatment.
AIM: Describe patients,' providers' and healthcare system leaders' perceptions of pharmacogenetic research to guide tobacco cessation treatment in an American Indian/Alaska Native primary care setting. MATERIALS & METHODS: This qualitative study used semistructured interviews with 20 American Indian/Alaska Native current or former tobacco users, 12 healthcare providers and nine healthcare system leaders. RESULTS:Participants supported pharmacogenetic research to guide tobacco cessation treatment provided that a community-based participatory research approach be employed, research closely coordinate with existing tobacco cessation services and access to pharmacogenetic test results be restricted to providers involved in tobacco cessation. CONCLUSION: Despite a history of mistrust toward genetic research in tribal communities, participants expressed willingness to support pharmacogenetic research to guide tobacco cessation treatment.
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