Literature DB >> 26838586

Can We Be Less Radical with Surgery for Early Cervical Cancer?

Madeleine C Macdonald1, John A Tidy2.   

Abstract

Although a rare cancer in the developed world due to the success of cervical screening programmes, cervical cancer remains one of the most common cancers diagnosed in women under the age of 35 years old. Radical hysterectomy and more recently radical trachelectomy have been highly effective in curing the majority of women with early stage disease. Many, however, are left with long-term 'survivorship' issues including bowel, bladder and sexual dysfunction. In view of these chronic co-morbidities, many clinicians now consider whether a less radical approach to surgery may be an option for some women. This review focuses on the current evidence for the safety of conservative surgery for early stage cervical cancer with regard to cure rates in comparison to standard management, as well as any improvement in short and long-term morbidity associated with a more conservative approach.

Entities:  

Keywords:  Cervical cancer; Hysterectomy; Lymphadenopathy; Morbidity; Outcome; Radical; Simple; Stage 1; Surgery

Mesh:

Year:  2016        PMID: 26838586     DOI: 10.1007/s11912-016-0501-5

Source DB:  PubMed          Journal:  Curr Oncol Rep        ISSN: 1523-3790            Impact factor:   5.075


  28 in total

Review 1.  Radiotherapy and chemoradiation after surgery for early cervical cancer.

Authors:  Linda Rogers; Shing Shun N Siu; David Luesley; Andrew Bryant; Heather O Dickinson
Journal:  Cochrane Database Syst Rev       Date:  2012-05-16

2.  Lymphedema and bladder-emptying difficulties after radical hysterectomy for early cervical cancer and among population controls.

Authors:  K Bergmark; E Avall-Lundqvist; P W Dickman; L Henningsohn; G Steineck
Journal:  Int J Gynecol Cancer       Date:  2006 May-Jun       Impact factor: 3.437

Review 3.  The surgical management of cervical cancer: an overview and literature review.

Authors:  Dario R Roque; Weiya Z Wysham; John T Soper
Journal:  Obstet Gynecol Surv       Date:  2014-07       Impact factor: 2.347

4.  Type II versus Type III nerve-sparing radical hysterectomy: comparison of lower urinary tract dysfunctions.

Authors:  Francesco Raspagliesi; Antonino Ditto; Rosanna Fontanelli; Flavia Zanaboni; Eugenio Solima; Gianbattista Spatti; Francesco Hanozet; Francesca Vecchione; Gabriella Rossi; Shigeki Kusamura
Journal:  Gynecol Oncol       Date:  2006-01-30       Impact factor: 5.482

Review 5.  Management of low-risk early-stage cervical cancer: should conization, simple trachelectomy, or simple hysterectomy replace radical surgery as the new standard of care?

Authors:  Pedro T Ramirez; Rene Pareja; Gabriel J Rendón; Carlos Millan; Michael Frumovitz; Kathleen M Schmeler
Journal:  Gynecol Oncol       Date:  2013-09-14       Impact factor: 5.482

Review 6.  Surgery for early stage cervical cancer: how radical should it be?

Authors:  Clare J Reade; Lua R Eiriksson; Allan Covens
Journal:  Gynecol Oncol       Date:  2013-07-14       Impact factor: 5.482

Review 7.  Diagnostic accuracy of tests for lymph node status in primary cervical cancer: a systematic review and meta-analysis.

Authors:  Tara J Selman; Christopher Mann; Javier Zamora; Tracy-Louise Appleyard; Khalid Khan
Journal:  CMAJ       Date:  2008-03-25       Impact factor: 8.262

8.  Total laparoscopic radical hysterectomy versus abdominal radical hysterectomy with lymphadenectomy in patients with early cervical cancer: our experience.

Authors:  Mario Malzoni; Raffaele Tinelli; Francesco Cosentino; Annarita Fusco; Carmine Malzoni
Journal:  Ann Surg Oncol       Date:  2009-02-18       Impact factor: 5.344

9.  Parametrial involvement in radical hysterectomy specimens for women with early-stage cervical cancer.

Authors:  Michael Frumovitz; Charlotte C Sun; Kathleen M Schmeler; Michael T Deavers; Ricardo Dos Reis; Charles F Levenback; Pedro T Ramirez
Journal:  Obstet Gynecol       Date:  2009-07       Impact factor: 7.661

10.  Feasibility and performance of lymphoscintigraphy in sentinel lymph node biopsy for early cervical cancer: results of the prospective multicenter SENTICOL study.

Authors:  Anne-Sophie Bats; Albane Frati; Marc Froissart; Isabelle Orliaguet; Denis Querleu; Slimane Zerdoud; Eric Leblanc; Hélène Gauthier; Catherine Uzan; Désirée Deandreis; Emile Darai; Khaldoun Kerrou; Henri Marret; Emilie Lenain; Patrice Mathevet; Fabrice Lecuru
Journal:  Ann Nucl Med       Date:  2014-11-15       Impact factor: 2.668

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  4 in total

1.  A novel 2-deoxy-2-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT)-based nomogram to predict lymph node metastasis in early stage uterine cervical squamous cell cancer.

Authors:  Shuai Liu; Zheng Feng; Jiajia Zhang; Huijuan Ge; Xiaohua Wu; Shaoli Song
Journal:  Quant Imaging Med Surg       Date:  2021-01

2.  Combining metformin and nelfinavir exhibits synergistic effects against the growth of human cervical cancer cells and xenograft in nude mice.

Authors:  Chenglai Xia; Ruihong Chen; Jinman Chen; Qianqian Qi; Yanbin Pan; Lanying Du; Guohong Xiao; Shibo Jiang
Journal:  Sci Rep       Date:  2017-03-02       Impact factor: 4.379

3.  Less radical surgery for women with early stage cervical cancer: Our experience on radical vaginal trachelectomy and laparoscopic pelvic lymphadenectomy.

Authors:  I Rizzuto; W MacNab; R Nicholson; M Nalam; B Rufford
Journal:  Gynecol Oncol Rep       Date:  2019-03-11

4.  Risk Factors of Regional Lymph Node Metastasis in Patients with Cervical Cancer.

Authors:  Chunchun Wu; Lichun Li; Xue Xiao; Anyi Sun; Wenji Lin; Ailu Li
Journal:  Open Life Sci       Date:  2019-06-24       Impact factor: 0.938

  4 in total

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