Literature DB >> 26838516

Nanoparticle-mediated photothermal effect enables a new method for quantitative biochemical analysis using a thermometer.

Guanglei Fu1, Sharma T Sanjay1, Maowei Dou1, XiuJun Li2.   

Abstract

A new biomolecular quantitation method, nanoparticle-mediated photothermal bioassay, using a common thermometer as the signal reader was developed. Using an immunoassay as a proof of concept, iron oxide nanoparticles (NPs) captured in the sandwich-type assay system were transformed into a near-infrared (NIR) laser-driven photothermal agent, Prussian blue (PB) NPs, which acted as a photothermal probe to convert the assay signal into heat through the photothermal effect, thus allowing sensitive biomolecular quantitation using a thermometer. This is the first report of biomolecular quantitation using a thermometer and also serves as the first attempt to introduce the nanoparticle-mediated photothermal effect for bioassays.

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Year:  2016        PMID： 26838516      PMCID： PMC5106188          DOI： 10.1039/c5nr09051b

Source DB:  PubMed          Journal:  Nanoscale        ISSN： 2040-3364            Impact factor:   7.790


  29 in total

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Review 4.  Recent progress in nanosensors for sensitive detection of biomolecules.

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5.  A homogeneous chemiluminescent immunoassay method.

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Review 7.  Nanoparticles for photothermal therapies.

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  18 in total

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Review 3.  Recent advances of controlled drug delivery using microfluidic platforms.

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Journal:  Adv Drug Deliv Rev       Date:  2017-09-15       Impact factor: 15.470

4.  Multiplexed Instrument-Free Bar-Chart SpinChip Integrated with Nanoparticle-Mediated Magnetic Aptasensors for Visual Quantitative Detection of Multiple Pathogens.

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5.  A Low-Cost Nanomaterial-based Electrochemical Immunosensor on Paper for High-Sensitivity Early Detection of Pancreatic Cancer.

Authors:  K Sudhakara Prasad; Xiyue Cao; Ning Gao; Qijie Jin; Sharma T Sanjay; Gilberto Henao-Pabon; XiuJun Li
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6.  A fully battery-powered inexpensive spectrophotometric system for high-sensitivity point-of-care analysis on a microfluidic chip.

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7.  Multiplexed instrument-free meningitis diagnosis on a polymer/paper hybrid microfluidic biochip.

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8.  Exploration of Nanoparticle-Mediated Photothermal Effect of TMB-H2O2 Colorimetric System and Its Application in a Visual Quantitative Photothermal Immunoassay.

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9.  Atomically Precise Au25(SG)18 Nanoclusters: Rapid Single-Step Synthesis and Application in Photothermal Therapy.

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10.  A sensitive photothermometric biosensor based on redox reaction-controlled nanoprobe conversion from Prussian blue to Prussian white.

Authors:  Xinyuan Zhang; Honghong Rao; Huiyi Huang; Kehui Zhang; Mingming Wei; Mingyue Luo; Xin Xue; Zhonghua Xue; Xiaoquan Lu
Journal:  Anal Bioanal Chem       Date:  2021-09-03       Impact factor: 4.142
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