Literature DB >> 26836031

Mutations acquired during cell culture isolation may affect antigenic characterisation of influenza A(H3N2) clade 3C.2a viruses.

Danuta M Skowronski1, Suzana Sabaiduc, Catharine Chambers, Alireza Eshaghi, Jonathan B Gubbay, Mel Krajden, Steven J Drews, Christine Martineau, Gaston De Serres, James A Dickinson, Anne-Luise Winter, Nathalie Bastien, Yan Li.   

Abstract

As elsewhere, few (< 15%) sentinel influenza A(H3N2) clade 3C.2a viruses that dominated in Canada during the 2014/15 season could be antigenically characterised by haemagglutination inhibition (HI) assay. Clade 3C.2a viruses that could be HI-characterised had acquired genetic mutations during in vitro cell culture isolation that modified the potential glycosylation motif found in original patient specimens and the consensus sequence of circulating viruses at amino acid positions 158-160 of the haemagglutinin protein. Caution is warranted in extrapolating antigenic relatedness based on limited HI findings for clade 3C.2a viruses that continue to circulate globally.

Entities:  

Keywords:  antigenic characterization; genomics; glycosylation; haemagglutination inhibition assay; influenza; influenza virus; influenza-like illness - ILI; vaccine-preventable diseases

Mesh：

Substances：

Year:  2016        PMID： 26836031     DOI： 10.2807/1560-7917.ES.2016.21.3.30112

Source DB:  PubMed          Journal:  Euro Surveill        ISSN： 1025-496X


  16 in total

1.  Serial Vaccination and the Antigenic Distance Hypothesis: Effects on Influenza Vaccine Effectiveness During A(H3N2) Epidemics in Canada, 2010-2011 to 2014-2015.

Authors:  Danuta M Skowronski; Catharine Chambers; Gaston De Serres; Suzana Sabaiduc; Anne-Luise Winter; James A Dickinson; Jonathan B Gubbay; Kevin Fonseca; Steven J Drews; Hugues Charest; Christine Martineau; Mel Krajden; Martin Petric; Nathalie Bastien; Yan Li; Derek J Smith
Journal:  J Infect Dis       Date:  2017-04-01       Impact factor: 5.226

Review 2.  The Unexpected Impact of Vaccines on Secondary Bacterial Infections Following Influenza.

Authors:  Amber M Smith; Victor C Huber
Journal:  Viral Immunol       Date:  2017-11-17       Impact factor: 2.257

3.  Measuring Influenza Neutralizing Antibody Responses to A(H3N2) Viruses in Human Sera by Microneutralization Assays Using MDCK-SIAT1 Cells.

Authors:  F Liaini Gross; Yaohui Bai; Stacie Jefferson; Crystal Holiday; Min Z Levine
Journal:  J Vis Exp       Date:  2017-11-22       Impact factor: 1.355

4.  The characteristics and antigenic properties of recently emerged subclade 3C.3a and 3C.2a human influenza A(H3N2) viruses passaged in MDCK cells.

Authors:  Yipu Lin; Stephen A Wharton; Lynne Whittaker; Mian Dai; Burcu Ermetal; Janice Lo; Andrea Pontoriero; Elsa Baumeister; Rodney S Daniels; John W McCauley
Journal:  Influenza Other Respir Viruses       Date:  2017-02-28       Impact factor: 4.380

5.  Interim estimates of 2016/17 vaccine effectiveness against influenza A(H3N2), Canada, January 2017.

Authors:  Danuta M Skowronski; Catharine Chambers; Suzana Sabaiduc; James A Dickinson; Anne-Luise Winter; Gaston De Serres; Steven J Drews; Agatha Jassem; Jonathan B Gubbay; Hugues Charest; Robert Balshaw; Nathalie Bastien; Yan Li; Mel Krajden
Journal:  Euro Surveill       Date:  2017-02-09

6.  Molecular Dynamics Simulation of the Influenza A(H3N2) Hemagglutinin Trimer Reveals the Structural Basis for Adaptive Evolution of the Recent Epidemic Clade 3C.2a.

Authors:  Masaru Yokoyama; Seiichiro Fujisaki; Masayuki Shirakura; Shinji Watanabe; Takato Odagiri; Kimito Ito; Hironori Sato
Journal:  Front Microbiol       Date:  2017-04-10       Impact factor: 5.640

Review 7.  The establishment of surrogates and correlates of protection: Useful tools for the licensure of effective influenza vaccines?

Authors:  Brian J Ward; Stephane Pillet; Nathalie Charland; Sonia Trepanier; Julie Couillard; Nathalie Landry
Journal:  Hum Vaccin Immunother       Date:  2018-01-16       Impact factor: 3.452

8.  Increase in Hospital Admissions for Severe Influenza A/B among Travelers on Cruise Ships to Alaska, 2015.

Authors:  Michael Payne; Danuta Skowronski; Suzana Sabaiduc; Linda Merrick; Christopher Lowe
Journal:  Emerg Infect Dis       Date:  2018-03       Impact factor: 6.883

9.  Characterization and Evolutionary Analysis of a Novel H3N2 Influenza A Virus Glycosylation Motif in Southern China.

Authors:  Zhiqi Zeng; Lee-Fong Yau; Zengxian Lin; Xuanzi Xia; Zifeng Yang; Jing-Rong Wang; Wenjun Song; Xinhua Wang
Journal:  Front Microbiol       Date:  2020-06-16       Impact factor: 5.640

10.  A Perfect Storm: Impact of Genomic Variation and Serial Vaccination on Low Influenza Vaccine Effectiveness During the 2014-2015 Season.

Authors:  Danuta M Skowronski; Catharine Chambers; Suzana Sabaiduc; Gaston De Serres; Anne-Luise Winter; James A Dickinson; Mel Krajden; Jonathan B Gubbay; Steven J Drews; Christine Martineau; Alireza Eshaghi; Trijntje L Kwindt; Nathalie Bastien; Yan Li
Journal:  Clin Infect Dis       Date:  2016-03-29       Impact factor: 9.079
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.