Literature DB >> 26833992

One-Shot Immunomodulatory Nanodiamond Agents for Cancer Immunotherapy.

Yu Zhang1, Zhifen Cui1, Huating Kong1, Kai Xia1, Liang Pan1, Jiang Li1, Yanhong Sun1, Jiye Shi2,3, Lihua Wang1, Ying Zhu1, Chunhai Fan1,4.   

Abstract

The use of functional nanodiamonds (fNDs) to deliver CpG oligonucleotides (ODNs) for sustained immunostimulation is reported. It is demonstrated that monotherapy using this immunostimulatory agent significantly suppresses the tumor growth in two murine tumor models. This fND-based nanoagent opens new opportunities for immunotherapy, as well as clinical applications of various types of therapeutic nucleic acids.
© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Year:  2016        PMID： 26833992     DOI： 10.1002/adma.201506232

Source DB:  PubMed          Journal:  Adv Mater        ISSN： 0935-9648            Impact factor:   30.849


  13 in total

1.  Potent and Prolonged Innate Immune Activation by Enzyme-Responsive Imidazoquinoline TLR7/8 Agonist Prodrug Vesicles.

Authors:  Bi Wang; Simon Van Herck; Yong Chen; Xiangyang Bai; Zifu Zhong; Kim Deswarte; Bart N Lambrecht; Niek N Sanders; Stefan Lienenklaus; Hans W Scheeren; Sunil A David; Fabian Kiessling; Twan Lammers; Bruno G De Geest; Yang Shi
Journal:  J Am Chem Soc       Date:  2020-06-30       Impact factor: 15.419

2.  Tumor selective uptake of drug-nanodiamond complexes improves therapeutic outcome in pancreatic cancer.

Authors:  Vijay S Madamsetty; Anil Sharma; Maria Toma; Stefanie Samaniego; Audrey Gallud; Enfeng Wang; Krishnendu Pal; Debabrata Mukhopadhyay; Bengt Fadeel
Journal:  Nanomedicine       Date:  2019-03-06       Impact factor: 5.307

3.  Antibody Conjugation of Fluorescent Nanodiamonds for Targeted Innate Immune Cell Activation.

Authors:  Lorena P Suarez-Kelly; Steven H Sun; Casey Ren; Isaac V Rampersaud; David Albertson; Megan C Duggan; Tiffany C Noel; Nicholas Courtney; Nathaniel J Buteyn; Charles Moritz; Lianbo Yu; Vedat O Yildiz; Jonathan P Butchar; Susheela Tridandapani; Arfaan A Rampersaud; William E Carson
Journal:  ACS Appl Nano Mater       Date:  2021-03-11

Review 4.  The era of bioengineering: how will this affect the next generation of cancer immunotherapy?

Authors:  Michele Graciotti; Cristiana Berti; Harm-Anton Klok; Lana Kandalaft
Journal:  J Transl Med       Date:  2017-06-19       Impact factor: 5.531

Review 5.  Nanomaterials in Targeting Cancer Stem Cells for Cancer Therapy.

Authors:  Weiwei Qin; Guan Huang; Zuanguang Chen; Yuanqing Zhang
Journal:  Front Pharmacol       Date:  2017-01-18       Impact factor: 5.810

6.  Self-healing microcapsules synergetically modulate immunization microenvironments for potent cancer vaccination.

Authors:  Xiaobo Xi; Tong Ye; Shuang Wang; Xiangming Na; Jianghua Wang; Shuang Qing; Xiaoyong Gao; Changlong Wang; Feng Li; Wei Wei; Guanghui Ma
Journal:  Sci Adv       Date:  2020-05-22       Impact factor: 14.136

7.  Pilot study on biocompatibility of fluorescent nanodiamond-(NV)-Z~800 particles in rats: safety, pharmacokinetics, and bio-distribution (part III).

Authors:  Frank C Barone; Cezary Marcinkiewicz; Jie Li; Mark Sternberg; Peter I Lelkes; Dmitriy A Dikin; Peter J Bergold; Jonathan A Gerstenhaber; Giora Feuerstein
Journal:  Int J Nanomedicine       Date:  2018-09-17

8.  An "all-in-one" antitumor and anti-recurrence/metastasis nanomedicine with multi-drug co-loading and burst drug release for multi-modality therapy.

Authors:  Ji-Chun Yang; Yue Shang; Yu-Hao Li; Yu Cui; Xue-Bo Yin
Journal:  Chem Sci       Date:  2018-07-30       Impact factor: 9.825

9.  Nanodiamond autophagy inhibitor allosterically improves the arsenical-based therapy of solid tumors.

Authors:  Zhifen Cui; Yu Zhang; Kai Xia; Qinglong Yan; Huating Kong; Jichao Zhang; Xiaolei Zuo; Jiye Shi; Lihua Wang; Ying Zhu; Chunhai Fan
Journal:  Nat Commun       Date:  2018-10-19       Impact factor: 14.919

10.  Fluorescent nanodiamonds encapsulated by Cowpea Chlorotic Mottle Virus (CCMV) proteins for intracellular 3D-trajectory analysis.

Authors:  Yingke Wu; Shuqin Cao; Md Noor A Alam; Marco Raabe; Sandra Michel-Souzy; Zuyuan Wang; Manfred Wagner; Anna Ermakova; Jeroen J L M Cornelissen; Tanja Weil
Journal:  J Mater Chem B       Date:  2021-07-21       Impact factor: 6.331
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