Literature DB >> 26833029

Upregulation of PI3K/AKT/mTOR, FABP5 and PPARβ/δ in Human Psoriasis and Imiquimod-induced Murine Psoriasiform Dermatitis Model.

Jean Christopher Chamcheu1, Maria-Ines Chaves-Rodriquez, Vaqar M Adhami, Imtiaz A Siddiqui, Gary S Wood, B Jack Longley, Hasan Mukhtar.   

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Year:  2016        PMID： 26833029      PMCID： PMC5540143          DOI： 10.2340/00015555-2359

Source DB:  PubMed          Journal:  Acta Derm Venereol        ISSN： 0001-5555            Impact factor:   4.437


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  15 in total

Review 1.  Cross-talk between mitogenic Ras/MAPK and survival PI3K/Akt pathways: a fine balance.

Authors:  Edita Aksamitiene; Anatoly Kiyatkin; Boris N Kholodenko
Journal:  Biochem Soc Trans       Date:  2012-02       Impact factor: 5.407

Review 2.  mTOR signaling in growth control and disease.

Authors:  Mathieu Laplante; David M Sabatini
Journal:  Cell       Date:  2012-04-13       Impact factor: 41.582

Review 3.  Severe psoriasis treated with a new macrolide: everolimus.

Authors:  E Frigerio; M D Colombo; C Franchi; A Altomare; C Garutti; G F Altomare
Journal:  Br J Dermatol       Date:  2007-02       Impact factor: 9.302

4.  Chemical chaperones protect epidermolysis bullosa simplex keratinocytes from heat stress-induced keratin aggregation: involvement of heat shock proteins and MAP kinases.

Authors:  Jean Christopher Chamcheu; Harshad Navsaria; Inger Pihl-Lundin; Mirjana Liovic; Anders Vahlquist; Hans Törmä
Journal:  J Invest Dermatol       Date:  2011-04-14       Impact factor: 8.551

5.  Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex.

Authors:  D D Sarbassov; David A Guertin; Siraj M Ali; David M Sabatini
Journal:  Science       Date:  2005-02-18       Impact factor: 47.728

Review 6.  Keratin gene mutations in disorders of human skin and its appendages.

Authors:  Jean Christopher Chamcheu; Imtiaz A Siddiqui; Deeba N Syed; Vaqar M Adhami; Mirjana Liovic; Hasan Mukhtar
Journal:  Arch Biochem Biophys       Date:  2010-12-19       Impact factor: 4.013

7.  Ribosomal protein S6 is hyperactivated and differentially phosphorylated in epidermal lesions of patients with psoriasis and atopic dermatitis.

Authors:  M T Ruf; A Andreoli; P Itin; G Pluschke; P Schmid
Journal:  Br J Dermatol       Date:  2014-11-09       Impact factor: 9.302

Review 8.  Contributions of peroxisome proliferator-activated receptor β/δ to skin health and disease.

Authors:  Alexandra Montagner; Walter Wahli
Journal:  Biomol Concepts       Date:  2013-02

Review 9.  Targeting the PI3K/Akt/mTOR pathway in hepatocellular carcinoma.

Authors:  Qian Zhou; Vivian W Y Lui; Winnie Yeo
Journal:  Future Oncol       Date:  2011-10       Impact factor: 3.404

Review 10.  Phosphoinositide-3 kinase/protein kinase-B/mammalian target of rapamycin pathway in psoriasis pathogenesis. A potential therapeutic target?

Authors:  Tian Huang; Xiran Lin; Xianmin Meng; Mao Lin
Journal:  Acta Derm Venereol       Date:  2014-07       Impact factor: 4.437
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  22 in total

1.  Dual Inhibition of PI3K/Akt and mTOR by the Dietary Antioxidant, Delphinidin, Ameliorates Psoriatic Features In Vitro and in an Imiquimod-Induced Psoriasis-Like Disease in Mice.

Authors:  Jean Christopher Chamcheu; Vaqar M Adhami; Stephane Esnault; Mario Sechi; Imtiaz A Siddiqui; Kenneth A Satyshur; Deeba N Syed; Shah-Jahan M Dodwad; Maria-Ines Chaves-Rodriquez; B Jack Longley; Gary S Wood; Hasan Mukhtar
Journal:  Antioxid Redox Signal       Date:  2016-10-04       Impact factor: 8.401

2.  Pityriasis rubra pilaris-like erythroderma secondary to phosphoinositide 3-kinase inhibition.

Authors:  A K Dewan; L Sowerby; S Jadeja; C Lian; P Wen; J R Brown; D C Fisher; N R LeBoeuf
Journal:  Clin Exp Dermatol       Date:  2018-05-30       Impact factor: 3.470

3.  [Expressions of survivin, PI3K and AKT in keratinocytes in skin lesions and their pathogenic role in psoriasis vulgaris].

Authors:  Hao Wang; Li-Wei Ran; Ke Hui; Xin-Yang Wang; Yan Zheng
Journal:  Nan Fang Yi Ke Da Xue Xue Bao       Date:  2017-11-20

4.  Serum amyloid A, an acute phase protein, stimulates proliferative and proinflammatory responses of keratinocytes.

Authors:  Ning Yu; Shujie Zhang; Jiajing Lu; Ying Li; Xuemei Yi; Li Tang; Lina Su; Yangfeng Ding
Journal:  Cell Prolif       Date:  2016-12-02       Impact factor: 6.831

5.  The Snowballing Literature on Imiquimod-Induced Skin Inflammation in Mice: A Critical Appraisal.

Authors:  Jason E Hawkes; Johann E Gudjonsson; Nicole L Ward
Journal:  J Invest Dermatol       Date:  2016-12-09       Impact factor: 8.551

6.  Bioactive Dietary VDR Ligands Regulate Genes Encoding Biomarkers of Skin Repair That Are Associated with Risk for Psoriasis.

Authors:  Amitis Karrys; Islam Rady; Roxane-Cherille N Chamcheu; Marya S Sabir; Sanchita Mallick; Jean Christopher Chamcheu; Peter W Jurutka; Mark R Haussler; G Kerr Whitfield
Journal:  Nutrients       Date:  2018-02-04       Impact factor: 5.717

7.  Inflammation dependent mTORC1 signaling interferes with the switch from keratinocyte proliferation to differentiation.

Authors:  Claudia Buerger; Nitesh Shirsath; Victoria Lang; Alina Berard; Sandra Diehl; Roland Kaufmann; Wolf-Henning Boehncke; Peter Wolf
Journal:  PLoS One       Date:  2017-07-10       Impact factor: 3.240

8.  Tumorigenic proteins upregulated in the MYCN-amplified IMR-32 human neuroblastoma cells promote proliferation and migration.

Authors:  Hayat Zaatiti; Jad Abdallah; Zeina Nasr; George Khazen; Anthony Sandler; Tamara J Abou-Antoun
Journal:  Int J Oncol       Date:  2018-01-04       Impact factor: 5.650

9.  The Protective Effects of 18β-Glycyrrhetinic Acid on Imiquimod-Induced Psoriasis in Mice via Suppression of mTOR/STAT3 Signaling.

Authors:  Haiming Chen; Huazhen Liu; Bin Tang; Yuchao Chen; Ling Han; Jingjie Yu; Yuhong Yan; Chuanjian Lu
Journal:  J Immunol Res       Date:  2020-08-27       Impact factor: 4.818

10.  Selective deletion of PPARβ/δ in fibroblasts causes dermal fibrosis by attenuated LRG1 expression.

Authors:  Ming Keat Sng; Jeremy Soon Kiat Chan; Ziqiang Teo; Terri Phua; Eddie Han Pin Tan; Jonathan Wei Kiat Wee; Nikki Jun Ning Koh; Chek Kun Tan; Jia Peng Chen; Mintu Pal; Benny Meng Kiat Tong; Ya Lin Tnay; Xuan Rui Ng; Pengcheng Zhu; Shunsuke Chiba; Xiaomeng Wang; Walter Wahli; Nguan Soon Tan
Journal:  Cell Discov       Date:  2018-04-03       Impact factor: 10.849
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