Literature DB >> 26826028

Treatment of full-thickness cartilage lesions and early OA using large condyle resurfacing prosthesis: UniCAP(®).

Jens Ole Laursen1.   

Abstract

PURPOSE: The UniCAP (®) implant for femoral resurfacing treatment of large cartilage lesions and early OA was introduced in 2006. The outcome of the present study is from a prospective cohort study of 64 patients, followed 2 years clinically and 7 years for revisions.
METHODS: From 2009 to 2013, 64 patients were treated with femoral resurfacing using the UniCAP implant. Indication for treatment with UniCAP implant was symptomatic huge cartilage lesion or early OA at the femoral condyle demonstrated by MRI or arthroscopy, which was ICRS grades 3-4 and more than 4 cm(2). There were 28 males and 36 females with a median age of 51 (range 35-65) years. Patients were followed for 2 years clinically with Knee Society subjective outcome scores (KSS), pain scores and radiographic evaluations and for 7 years with complications and reoperations.
RESULTS: At 2 years, the follow-up mean KSS improved from 49 (6.9) to 88 (17.1), the mean KSS function score improved from 46 (8.0) to 90 (17.1), and the mean Pain score improved from 7.4 (0.5) to 2.3 (1.4). 47 % of the implants were revised within 7 years to arthroplasty due to the progression of cartilage lesions, progressing of osteoarthritis or increased knee pain. The reoperation rate did not show any significant difference between females and males. The Kaplan-Meier survival rate was 50 % at 7 years, no difference among females and males.
CONCLUSION: The present study demonstrated an improved subjective outcome and reduced pain after femoral resurfacing using the UniCAP (®) implant in a relatively large cohort of patients with symptomatic large cartilage lesions or early OA. A 47 % reoperation rate with conversion to arthroplasty was found. The femoral resurfacing implantation can be a temporary treatment for large cartilage lesions or early OA that is expected to develop into osteoarthritis. For younger patients who are ineligible for arthroplasty treatment, this implant can offer a temporary solution. LEVEL OF EVIDENCE: IV.

Entities:  

Keywords:  Condylar implant; Early OA; Femoral resurfacing; Knee prosthesis; Large cartilage lesions

Mesh:

Year:  2016        PMID: 26826028     DOI: 10.1007/s00167-016-4000-x

Source DB:  PubMed          Journal:  Knee Surg Sports Traumatol Arthrosc        ISSN: 0942-2056            Impact factor:   4.342


  23 in total

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Review 4.  UniCAP as an alternative for unicompartmental arthritis.

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Journal:  Clin Sports Med       Date:  2014-01       Impact factor: 2.182

5.  Results after microfracture of full-thickness chondral defects in different compartments in the knee.

Authors:  P C Kreuz; M R Steinwachs; C Erggelet; S J Krause; G Konrad; M Uhl; N Südkamp
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7.  The microfracture technique for the treatment of articular cartilage lesions in the knee. A prospective cohort study.

Authors:  Kai Mithoefer; Riley J Williams; Russell F Warren; Hollis G Potter; Christopher R Spock; Edward C Jones; Thomas L Wickiewicz; Robert G Marx
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8.  Safety of, and biological and functional response to, a novel metallic implant for the management of focal full-thickness cartilage defects: Preliminary assessment in an animal model out to 1 year.

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9.  Is microfracture of chondral defects in the knee associated with different results in patients aged 40 years or younger?

Authors:  Peter C Kreuz; Christoph Erggelet; Matthias R Steinwachs; Stefanie J Krause; Andreas Lahm; Philipp Niemeyer; Nadir Ghanem; Markus Uhl; Norbert Südkamp
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Authors:  Jens Ole Laursen
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2016-10-06       Impact factor: 4.342

5.  Accurate Reporting of Concomitant Procedures Is Highly Variable in Studies Investigating Knee Cartilage Restoration.

Authors:  William L Sheppard; Betina B Hinckel; Armin Arshi; Seth L Sherman; Kristofer J Jones
Journal:  Cartilage       Date:  2019-04-11       Impact factor: 4.634

6.  Treatment of Unicompartmental Cartilage Defects of the Knee with Unicompartmental Knee Arthroplasty, Patellofemoral Partial Knee Arthroplasty or Focal Resurfacing.

Authors:  Bernhard Springer; Friedrich Boettner
Journal:  Life (Basel)       Date:  2021-04-27

7.  Successful Treatment of Femoral Chondral Lesions with a Novel Customized Metal Implant at Midterm Follow-Up.

Authors:  Nicolas Martinez-Carranza; Peter Rockborn; David Roberts; Magnus Högström; Anders Stålman
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8.  The clinical outcome of the different HemiCAP and UniCAP knee implants: A systematic and comprehensive review.

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9.  A longterm prospective follow-up study of resurfacing miniprosthesis suitable for patients above sixtyfive years with localized cartilage lesions or early osteoarthritis in the knee.

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