Literature DB >> 26815015

A new dimeric anthraquinone from endophytic Talaromyces sp. YE3016.

Xiao-Song Xie1, Xiao-Wei Fang1, Rong Huang2, Shou-Peng Zhang1, Hong-Xia Wei1, Shao-Hua Wu1.   

Abstract

A new unsymmetrical dimeric anthraquinone, 3-demethyl-3-(2-hydroxypropyl)-skyrin (1) was isolated from the solid-state fermentation extract of an endophytic fungal strain Talaromyces sp. YE 3016, together with five known compounds, skyrin (2), oxyskyrin (3), emodin (4), 1,3,6-trihydroxy-8-methyl-anthraquinone (5) and ergosterol (6). The structure of the new compound was elucidated on the basis of spectroscopic analysis. Compounds 1-3 exhibited moderate cytotoxic activities against MCF-7 cell line.

Entities:  

Keywords:  Talaromyces sp; dimeric anthraquinone; endophytic fungi; skyrin

Mesh：

Substances：

Year:  2016        PMID： 26815015     DOI： 10.1080/14786419.2015.1136888

Source DB:  PubMed          Journal:  Nat Prod Res        ISSN： 1478-6419            Impact factor:   2.861


  7 in total

Review 1.  Diverse host-associated fungal systems as a dynamic source of novel bioactive anthraquinones in drug discovery: Current status and future perspectives.

Authors:  Zeinab T Shakour; Mohamed A Farag
Journal:  J Adv Res       Date:  2021-11-22       Impact factor: 12.822

2.  Diversity and Antimicrobial Activity of Culturable Fungal Endophytes in Solanum mauritianum.

Authors:  Sharon Pelo; Vuyo Mavumengwana; Ezekiel Green
Journal:  Int J Environ Res Public Health       Date:  2020-01-09       Impact factor: 3.390

3.  Bioactive Metabolites From Acid-Tolerant Fungi in a Thai Mangrove Sediment.

Authors:  Hai Gao; Yanan Wang; Qiao Luo; Liyuan Yang; Xingxing He; Jun Wu; Konthorn Kachanuban; Pongthep Wilaipun; Weiming Zhu; Yi Wang
Journal:  Front Microbiol       Date:  2021-01-22       Impact factor: 5.640

4.  Endophytic fungi: A treasure trove of novel anticancer compounds.

Authors:  Jignesh Prajapati; Dweipayan Goswami; Rakesh M Rawal
Journal:  Curr Res Pharmacol Drug Discov       Date:  2021-09-01

Review 5.  Research advances in the structures and biological activities of secondary metabolites from Talaromyces.

Authors:  Li-Rong Lei; Lei-Qiang Gong; Meng-Ying Jin; Rui Wang; Ran Liu; Jing Gao; Meng-Dan Liu; Li Huang; Guang-Zhi Wang; Dong Wang; Yun Deng
Journal:  Front Microbiol       Date:  2022-08-19       Impact factor: 6.064

6.  Two New Diphenylketones and a New Xanthone from Talaromyces islandicus EN-501, an Endophytic Fungus Derived from the Marine Red Alga Laurencia okamurai.

Authors:  Hong-Lei Li; Xiao-Ming Li; Hui Liu; Ling-Hong Meng; Bin-Gui Wang
Journal:  Mar Drugs       Date:  2016-12-07       Impact factor: 5.118

7.  MALDI-HRMS Imaging Maps the Localization of Skyrin, the Precursor of Hypericin, and Pathway Intermediates in Leaves of Hypericum Species.

Authors:  Bharadwaj Revuru; Miroslava Bálintová; Jana Henzelyová; Eva Čellárová; Souvik Kusari
Journal:  Molecules       Date:  2020-08-31       Impact factor: 4.411
  7 in total

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