M Bade1, V Bähr2, U Brandt3, A Eigentopf4, T Brüchert5, M-L Gross4, E Motsch4, N Becker6. 1. Outpatient Orthopedics Hospital (ZAR), Ludwigshafen, Germany. 2. Faculty of Applied Psychology, SRH Hochschule Heidelberg, Heidelberg, Germany. 3. Psychiatrisches Zentrum Nordbaden, Wiesloch, Germany. 4. Division of Cancer Epidemiology, German Cancer Research Center, Im Neuenheimer Feld 581, 69120, Heidelberg, Germany. 5. University of Bremen, Bremen, Germany. 6. Division of Cancer Epidemiology, German Cancer Research Center, Im Neuenheimer Feld 581, 69120, Heidelberg, Germany. n.becker@dkfz.de.
Abstract
INTRODUCTION: In the German lung cancer screening trial LUSI, smoking cessation counseling (SCC) was offered to all participants at time of randomization, and smoking habits were asked for within annual questionnaire inquiries. We analyzed the smoking habits of the participants within the first 2 years of follow-up and especially the potential effect of the SCC on these habits. MATERIALS AND METHODS: We used the smoking data of the initial inquiry on which the decision on invitation to the study was based, the socio-economic data of the questionnaire filled-in at time of randomization, the psycho-social data obtained during the SCC, and the annual questionnaire data of the first two annual follow-up screening rounds. RESULTS:Smoking prevalence decreased in the entire cohort significantly by 4 %, whereby the decrease was with 4.5 % statistically not significantly higher in the control arm than in the screening arm with 3.4 %. The decline was much stronger in the subgroup of attendees to stop-smoking counseling and mounted up therein to 10 %. In some participants, an increase of readiness to quit smoking was observed during the counseling hour, but did not show effects on smoking status 2 years later. DISCUSSION: We did not see a tendency to increased smoking among participants of the intervention arm or the entire study. The decline of smoking prevalence among the attendees of the counseling might be due to self-selection. Since the issue of effectiveness of smoking cessation counseling is important, further research with randomization into offering counseling or no intervention should be taken into consideration.
RCT Entities:
INTRODUCTION: In the German lung cancer screening trial LUSI, smoking cessation counseling (SCC) was offered to all participants at time of randomization, and smoking habits were asked for within annual questionnaire inquiries. We analyzed the smoking habits of the participants within the first 2 years of follow-up and especially the potential effect of the SCC on these habits. MATERIALS AND METHODS: We used the smoking data of the initial inquiry on which the decision on invitation to the study was based, the socio-economic data of the questionnaire filled-in at time of randomization, the psycho-social data obtained during the SCC, and the annual questionnaire data of the first two annual follow-up screening rounds. RESULTS: Smoking prevalence decreased in the entire cohort significantly by 4 %, whereby the decrease was with 4.5 % statistically not significantly higher in the control arm than in the screening arm with 3.4 %. The decline was much stronger in the subgroup of attendees to stop-smoking counseling and mounted up therein to 10 %. In some participants, an increase of readiness to quit smoking was observed during the counseling hour, but did not show effects on smoking status 2 years later. DISCUSSION: We did not see a tendency to increased smoking among participants of the intervention arm or the entire study. The decline of smoking prevalence among the attendees of the counseling might be due to self-selection. Since the issue of effectiveness of smoking cessation counseling is important, further research with randomization into offering counseling or no intervention should be taken into consideration.
Authors: Lisa Sanderson Cox; Matthew M Clark; James R Jett; Christi A Patten; Darrell R Schroeder; Liza M Nirelli; Stephen J Swensen; Richard D Hurt Journal: Cancer Date: 2003-12-01 Impact factor: 6.860
Authors: Carlijn Michelle van der Aalst; Karien Anna Margaretha van den Bergh; Marc Christiaan Willemsen; Henricus Johannes de Koning; Robertus Johannes van Klaveren Journal: Thorax Date: 2010-07 Impact factor: 9.139
Authors: Cynthia O Townsend; Matthew M Clark; James R Jett; Christi A Patten; Darrell R Schroeder; Liza M Nirelli; Stephen J Swensen; Richard D Hurt Journal: Cancer Date: 2005-05-15 Impact factor: 6.860
Authors: N Becker; E Motsch; M-L Gross; A Eigentopf; C P Heussel; H Dienemann; P A Schnabel; L Pilz; M Eichinger; D-E Optazaite; M Puderbach; J Tremper; S Delorme Journal: J Cancer Res Clin Oncol Date: 2012-04-21 Impact factor: 4.553
Authors: Mindi A Styn; Stephanie R Land; Kenneth A Perkins; David O Wilson; Marjorie Romkes; Joel L Weissfeld Journal: Cancer Epidemiol Biomarkers Prev Date: 2009-12 Impact factor: 4.254
Authors: John K Field; Rob van Klaveren; Jesper H Pedersen; Ugo Pastorino; Eugino Paci; Nikolauss Becker; Maurizo Infante; Matthijs Oudkerk; Harry J de Koning Journal: J Surg Oncol Date: 2013-07-25 Impact factor: 3.454
Authors: Bertram J Jobst; Oliver Weinheimer; Mila Trauth; Nikolaus Becker; Erna Motsch; Marie-Luise Groß; Jan Tremper; Stefan Delorme; Anke Eigentopf; Monika Eichinger; Hans-Ulrich Kauczor; Mark O Wielpütz Journal: Eur Radiol Date: 2017-09-07 Impact factor: 5.315
Authors: Hasmeena Kathuria; Frank C Detterbeck; Joelle T Fathi; Kathleen Fennig; Michael K Gould; Denise G Jolicoeur; Stephanie R Land; Greta M Massetti; Peter J Mazzone; Gerard A Silvestri; Christopher G Slatore; Robert A Smith; Anil Vachani; Steven B Zeliadt; Renda Soylemez Wiener Journal: Am J Respir Crit Care Med Date: 2017-11-01 Impact factor: 30.528
Authors: Giulia Veronesi; David R Baldwin; Claudia I Henschke; Simone Ghislandi; Sergio Iavicoli; Matthijs Oudkerk; Harry J De Koning; Joseph Shemesh; John K Field; Javier J Zulueta; Denis Horgan; Lucia Fiestas Navarrete; Maurizio Valentino Infante; Pierluigi Novellis; Rachael L Murray; Nir Peled; Cristiano Rampinelli; Gaetano Rocco; Witold Rzyman; Giorgio Vittorio Scagliotti; Martin C Tammemagi; Luca Bertolaccini; Natthaya Triphuridet; Rowena Yip; Alexia Rossi; Suresh Senan; Giuseppe Ferrante; Kate Brain; Carlijn van der Aalst; Lorenzo Bonomo; Dario Consonni; Jan P Van Meerbeeck; Patrick Maisonneuve; Silvia Novello; Anand Devaraj; Zaigham Saghir; Giuseppe Pelosi Journal: Cancers (Basel) Date: 2020-06-24 Impact factor: 6.639