Ghaeth H Yassen1, Ruijie Huang2, Afnan Al-Zain2,3, Takamitsu Yoshida2, Richard L Gregory2, Jeffrey A Platt2. 1. Department of Biomedical and Applied Sciences, Indiana University School of Dentistry, 1121 W Michigan St, Indianapolis, IN, 46202, USA. gyassen@iupui.edu. 2. Department of Biomedical and Applied Sciences, Indiana University School of Dentistry, 1121 W Michigan St, Indianapolis, IN, 46202, USA. 3. Division of Operative Dentistry, Faculty of Dentistry, Department of Conservative Sciences, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.
Abstract
OBJECTIVE: This study evaluated selected properties of a prototype root repair cement containing surface pre-reacted glass ionomer fillers (S-PRG) in comparison to mineral trioxide aggregate (MTA) and intermediate restorative material (IRM). MATERIALS AND METHODS: The antibacterial effect of S-PRG, MTA, and IRM cements was tested against Porphyromonas gingivalis and Enterococcus faecalis after 1 and 3 days of aging of the cements. The set cements were immersed in distilled water for 4 h to 28 days, and ion-releasing ability was evaluated. Initial and final setting times of all cements were evaluated using Gilmore needles. The push-out bond strength between radicular dentin and all cements was tested at different levels of the roots. RESULTS: S-PRG and IRM cements, but not MTA cement, demonstrated significant antibacterial effect against P. gingivalis. All types of cements exhibited significant antibacterial effect against E. faecalis without being able to eliminate the bacterium. S-PRG cement provided continuous release of fluoride, strontium, boron, sodium, aluminum, and zinc throughout all tested time points. Both initial and final setting times were significantly shorter for S-PRG and IRM cements in comparison to MTA. The push-out bond strength was significantly lower for S-PRG cement in comparison to MTA and IRM at coronal and middle levels of the roots. CONCLUSIONS: S-PRG cement demonstrated significant antibacterial effects against endodontic pathogens, multiple ion-releasing ability, relatively short setting time, and low bonding strength. CLINICAL RELEVANCE: S-PRG cement can be used as a one-visit root repair material with promising antibacterial properties and ion-releasing capacity.
OBJECTIVE: This study evaluated selected properties of a prototype root repair cement containing surface pre-reacted glass ionomer fillers (S-PRG) in comparison to mineral trioxide aggregate (MTA) and intermediate restorative material (IRM). MATERIALS AND METHODS: The antibacterial effect of S-PRG, MTA, and IRM cements was tested against Porphyromonas gingivalis and Enterococcus faecalis after 1 and 3 days of aging of the cements. The set cements were immersed in distilled water for 4 h to 28 days, and ion-releasing ability was evaluated. Initial and final setting times of all cements were evaluated using Gilmore needles. The push-out bond strength between radicular dentin and all cements was tested at different levels of the roots. RESULTS: S-PRG and IRM cements, but not MTA cement, demonstrated significant antibacterial effect against P. gingivalis. All types of cements exhibited significant antibacterial effect against E. faecalis without being able to eliminate the bacterium. S-PRG cement provided continuous release of fluoride, strontium, boron, sodium, aluminum, and zinc throughout all tested time points. Both initial and final setting times were significantly shorter for S-PRG and IRM cements in comparison to MTA. The push-out bond strength was significantly lower for S-PRG cement in comparison to MTA and IRM at coronal and middle levels of the roots. CONCLUSIONS: S-PRG cement demonstrated significant antibacterial effects against endodontic pathogens, multiple ion-releasing ability, relatively short setting time, and low bonding strength. CLINICAL RELEVANCE: S-PRG cement can be used as a one-visit root repair material with promising antibacterial properties and ion-releasing capacity.
Entities:
Keywords:
IRM; Ion release; MTA; Push-out bond strength; S-PRG fillers; Setting time
Authors: F M Collares; F F Portella; S B Rodrigues; R K Celeste; V C B Leitune; S M W Samuel Journal: Int Endod J Date: 2015-09-22 Impact factor: 5.264
Authors: K T Shalumon; S Sowmya; D Sathish; K P Chennazhi; Shantikumar V Nair; R Jayakumar Journal: J Biomed Nanotechnol Date: 2013-03 Impact factor: 4.099
Authors: Ghaeth H Yassen; Frank Lippert; George Eckert; Jennifer Eder; Andrea Ferreira Zandoná Journal: Quintessence Int Date: 2012 Jul-Aug Impact factor: 1.677
Authors: Frederico C Martinho; Fábio R M Leite; Gustavo G Nascimento; Joni A Cirelli; Brenda P F A Gomes Journal: Clin Oral Investig Date: 2014-02-13 Impact factor: 3.573
Authors: Amjad Abu Hasna; Ana Luisa Theodoro; Larissa Marques Pereira; Lucas de Paula Ramos; Tiago Moreira Bastos Campos; Maisour Ala Rachi; Talal Al-Nahalwi; Luciane Dias de Oliveira; Cláudio Antonio Talge Carvalho Journal: Biomed Res Int Date: 2022-05-10 Impact factor: 3.246