Literature DB >> 26774880

Blood circulating tumor DNA for non-invasive genotyping of colon cancer patients.

Giulia Siravegna1, Alberto Bardelli2.   

Abstract

Most solid tumors, including colorectal cancers, shed cell-free DNA (ctDNA) in the blood. ctDNA can be analyzed to generate molecular profiles which capture the heterogeneity of the disease more comprehensively then tumor tissue biopsies. This approach commonly called 'liquid biopsy' can be applied to monitor response to therapy, to assess minimal residual disease and to uncover the emergence of drug resistance. This review will discuss current and future developments of ctDNA analysis in the clinical management of colorectal cancer patients.
Copyright © 2015. Published by Elsevier B.V.

Entities:  

Keywords:  Circulating tumor DNA; Colorectal cancer; Liquid biopsy; Targeted therapy

Mesh：

Substances：

Year:  2015        PMID： 26774880      PMCID： PMC5528968          DOI： 10.1016/j.molonc.2015.12.005

Source DB:  PubMed          Journal:  Mol Oncol        ISSN： 1574-7891            Impact factor:   6.603


  45 in total

1.  Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer.

Authors:  Sandra Misale; Rona Yaeger; Sebastijan Hobor; Elisa Scala; Manickam Janakiraman; David Liska; Emanuele Valtorta; Roberta Schiavo; Michela Buscarino; Giulia Siravegna; Katia Bencardino; Andrea Cercek; Chin-Tung Chen; Silvio Veronese; Carlo Zanon; Andrea Sartore-Bianchi; Marcello Gambacorta; Margherita Gallicchio; Efsevia Vakiani; Valentina Boscaro; Enzo Medico; Martin Weiser; Salvatore Siena; Federica Di Nicolantonio; David Solit; Alberto Bardelli
Journal:  Nature       Date:  2012-06-28       Impact factor: 49.962

2.  Reproducibility of a semiquantitative measurement of circulating DNA in plasma from neoplastic patients.

Authors:  Milo Frattini; Debora Balestra; Paolo Verderio; Gianfrancesco Gallino; Ermanno Leo; Gabriella Sozzi; Marco A Pierotti; Maria Grazia Daidone
Journal:  J Clin Oncol       Date:  2005-05-01       Impact factor: 44.544

3.  Increased integrity of free circulating DNA in sera of patients with colorectal or periampullary cancer: direct quantitative PCR for ALU repeats.

Authors:  Naoyuki Umetani; Joseph Kim; Suzanne Hiramatsu; Howard A Reber; Oscar J Hines; Anton J Bilchik; Dave S B Hoon
Journal:  Clin Chem       Date:  2006-06       Impact factor: 8.327

4.  Tracking tumor resistance using 'liquid biopsies'.

Authors:  Klaus Pantel; Luis A Diaz; Kornelia Polyak
Journal:  Nat Med       Date:  2013-06       Impact factor: 53.440

5.  Detection of KRAS mutations in colorectal cancer by high-resolution melting analysis.

Authors:  E S K Ma; C L P Wong; F B F Law; W-K Chan; D Siu
Journal:  J Clin Pathol       Date:  2009-10       Impact factor: 3.411

6.  Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients.

Authors:  Giulia Siravegna; Benedetta Mussolin; Michela Buscarino; Giorgio Corti; Andrea Cassingena; Giovanni Crisafulli; Agostino Ponzetti; Chiara Cremolini; Alessio Amatu; Calogero Lauricella; Simona Lamba; Sebastijan Hobor; Antonio Avallone; Emanuele Valtorta; Giuseppe Rospo; Enzo Medico; Valentina Motta; Carlotta Antoniotti; Fabiana Tatangelo; Beatriz Bellosillo; Silvio Veronese; Alfredo Budillon; Clara Montagut; Patrizia Racca; Silvia Marsoni; Alfredo Falcone; Ryan B Corcoran; Federica Di Nicolantonio; Fotios Loupakis; Salvatore Siena; Andrea Sartore-Bianchi; Alberto Bardelli
Journal:  Nat Med       Date:  2015-06-01       Impact factor: 53.440

Review 7.  Liquid biopsies: genotyping circulating tumor DNA.

Authors:  Luis A Diaz; Alberto Bardelli
Journal:  J Clin Oncol       Date:  2014-01-21       Impact factor: 44.544

8.  Analysis of circulating tumour DNA to monitor disease burden following colorectal cancer surgery.

Authors:  Thomas Reinert; Lone V Schøler; Rune Thomsen; Heidi Tobiasen; Søren Vang; Iver Nordentoft; Philippe Lamy; Anne-Sofie Kannerup; Frank V Mortensen; Katrine Stribolt; Stephen Hamilton-Dutoit; Hans J Nielsen; Søren Laurberg; Niels Pallisgaard; Jakob S Pedersen; Torben F Ørntoft; Claus L Andersen
Journal:  Gut       Date:  2015-02-04       Impact factor: 23.059

9.  Metabolic DNA as the origin of spontaneously released DNA?

Authors:  Peter B Gahan; Philippe Anker; Maurice Stroun
Journal:  Ann N Y Acad Sci       Date:  2008-08       Impact factor: 5.691

10.  A molecularly annotated platform of patient-derived xenografts ("xenopatients") identifies HER2 as an effective therapeutic target in cetuximab-resistant colorectal cancer.

Authors:  Andrea Bertotti; Giorgia Migliardi; Francesco Galimi; Francesco Sassi; Davide Torti; Claudio Isella; Davide Corà; Federica Di Nicolantonio; Michela Buscarino; Consalvo Petti; Dario Ribero; Nadia Russolillo; Andrea Muratore; Paolo Massucco; Alberto Pisacane; Luca Molinaro; Emanuele Valtorta; Andrea Sartore-Bianchi; Mauro Risio; Lorenzo Capussotti; Marcello Gambacorta; Salvatore Siena; Enzo Medico; Anna Sapino; Silvia Marsoni; Paolo M Comoglio; Alberto Bardelli; Livio Trusolino
Journal:  Cancer Discov       Date:  2011-09-02       Impact factor: 39.397
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  22 in total

1.  Hybrid Capture-Based Genomic Profiling of Circulating Tumor DNA from Patients with Advanced Cancers of the Gastrointestinal Tract or Anus.

Authors:  Alexa B Schrock; Dean Pavlick; Samuel J Klempner; Jon H Chung; Brady Forcier; Allison Welsh; Lauren Young; Bryan Leyland-Jones; Rodolfo Bordoni; Richard D Carvajal; Joseph Chao; Razelle Kurzrock; Jason K Sicklick; Jeffrey S Ross; Philip J Stephens; Craig Devoe; Fadi Braiteh; Siraj M Ali; Vincent A Miller
Journal:  Clin Cancer Res       Date:  2018-01-23       Impact factor: 12.531

Review 2.  Pathologists and liquid biopsies: to be or not to be?

Authors:  Paul Hofman; Helmut H Popper
Journal:  Virchows Arch       Date:  2016-08-23       Impact factor: 4.064

Review 3.  Blood circulating tumor DNA for non-invasive genotyping of colon cancer patients.

Authors:  Giulia Siravegna; Alberto Bardelli
Journal:  Mol Oncol       Date:  2015-12-17       Impact factor: 6.603

4.  EGFR Amplification in Metastatic Colorectal Cancer.

Authors:  Giovanni Randon; Rona Yaeger; Jaclyn F Hechtman; Paolo Manca; Giovanni Fucà; Henry Walch; Jeeyun Lee; Elena Élez; Jenny Seligmann; Benedetta Mussolin; Filippo Pagani; Marco Maria Germani; Margherita Ambrosini; Daniele Rossini; Margherita Ratti; Francesc Salvà; Susan D Richman; Henry Wood; Gouri Nanjangud; Annunziata Gloghini; Massimo Milione; Alberto Bardelli; Filippo de Braud; Federica Morano; Chiara Cremolini; Filippo Pietrantonio
Journal:  J Natl Cancer Inst       Date:  2021-11-02       Impact factor: 13.506

5.  The changing face of clinical trials in the personalized medicine and immuno-oncology era: report from the international congress on clinical trials in Oncology & Hemato-Oncology (ICTO 2017).

Authors:  Talia Golan; Michele Milella; Aliza Ackerstein; Ranaan Berger
Journal:  J Exp Clin Cancer Res       Date:  2017-12-28

Review 6.  Circulating Tumor DNA as Biomarkers for Cancer Detection.

Authors:  Xiao Han; Junyun Wang; Yingli Sun
Journal:  Genomics Proteomics Bioinformatics       Date:  2017-04-07       Impact factor: 7.691

Review 7.  Prognostic value of EGFR and KRAS in circulating tumor DNA in patients with advanced non-small cell lung cancer: a systematic review and meta-analysis.

Authors:  Gaowei Fan; Kuo Zhang; Jiansheng Ding; Jinming Li
Journal:  Oncotarget       Date:  2017-05-16

8.  Can molecular biomarkers replace a clinical risk score for resectable colorectal liver metastasis?

Authors:  Torhild Veen; Kjetil Søreide
Journal:  World J Gastrointest Oncol       Date:  2017-03-15

9.  Simultaneous multiple single nucleotide polymorphism detection based on click chemistry combined with DNA-encoded probes.

Authors:  Qian-Yu Zhou; Fang Yuan; Xiao-Hui Zhang; Ying-Lin Zhou; Xin-Xiang Zhang
Journal:  Chem Sci       Date:  2018-02-22       Impact factor: 9.825

10.  Circulating Tumor DNA Predicts Pathologic and Clinical Outcomes Following Neoadjuvant Chemoradiation and Surgery for Patients With Locally Advanced Rectal Cancer.

Authors:  Susan G R McDuff; Karin M Hardiman; Peter J Ulintz; Aparna R Parikh; Hui Zheng; Daniel W Kim; Jochen K Lennerz; Mehlika Hazar-Rethinam; Emily E Van Seventer; Isobel J Fetter; Brandon Nadres; Christine E Eyler; David P Ryan; Colin D Weekes; Jeffrey W Clark; James C Cusack; Lipika Goyal; Andrew X Zhu; Jennifer Y Wo; Lawrence S Blaszkowsky; Jill Allen; Ryan B Corcoran; Theodore S Hong
Journal:  JCO Precis Oncol       Date:  2021-01-12
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