Literature DB >> 26730229

Anesthetic Considerations for Intraoperative Radiation Therapy.

Kathryn M Glynn1, Adam I Riker2.   

Abstract

BACKGROUND: Formerly, anesthetized patients who received intraoperative radiation therapy (IORT) had to be transported from the operating room (OR) to the location of the linear accelerator. With the advent of mobile accelerators, therapy is delivered directly to the patient in the OR, presenting specific challenges for the anesthesiologist.
METHODS: We review the uses and benefits, operative and anesthetic challenges, and unique issues associated with IORT.
RESULTS: Patient safety and precise delivery of the radiation dose are the primary goals of IORT. The anesthesiologist's role in ensuring the success of these two outcomes includes selecting the optimal anesthetic technique to prevent patient movement and permit sentinel node mapping, monitoring the patient's vital signs throughout the procedure, and ensuring that the sterile field is maintained in the OR.
CONCLUSION: Although keeping patients in the OR has simplified the process of providing IORT, the anesthesiologist must be aware of potential problems and plan accordingly.

Entities:  

Keywords:  Monitoring–intraoperative; particle accelerators; radiotherapy

Year:  2015        PMID: 26730229      PMCID: PMC4679306     

Source DB:  PubMed          Journal:  Ochsner J        ISSN: 1524-5012


  4 in total

1.  The Mobetron: a new concept for IORT.

Authors:  M L Meurk; D A Goer; G Spalek; T Cook
Journal:  Front Radiat Ther Oncol       Date:  1997

2.  Targeted intraoperative radiotherapy versus whole breast radiotherapy for breast cancer (TARGIT-A trial): an international, prospective, randomised, non-inferiority phase 3 trial.

Authors:  Jayant S Vaidya; David J Joseph; Jeffrey S Tobias; Max Bulsara; Frederik Wenz; Christobel Saunders; Michael Alvarado; Henrik L Flyger; Samuele Massarut; Wolfgang Eiermann; Mohammed Keshtgar; John Dewar; Uta Kraus-Tiefenbacher; Marc Sütterlin; Laura Esserman; Helle M R Holtveg; Mario Roncadin; Steffi Pigorsch; Marinos Metaxas; Mary Falzon; April Matthews; Tammy Corica; Norman R Williams; Michael Baum
Journal:  Lancet       Date:  2010-07-10       Impact factor: 79.321

3.  Shielding assessment of a mobile electron accelerator for intraoperative radiotherapy.

Authors:  J L Daves; M D Mills
Journal:  J Appl Clin Med Phys       Date:  2001       Impact factor: 2.102

4.  Preliminary clinical experience with intraoperative radiotherapy.

Authors:  A L Goldson
Journal:  J Natl Med Assoc       Date:  1978-07       Impact factor: 1.798

  4 in total

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