Literature DB >> 26720884

Adjunctive dental therapy via tooth plaque reduction and gingivitis treatment by blue light-emitting diodes tooth brushing.

Elina A Genina1, Vladimir A Titorenko2, Andrey V Belikov3, Alexey N Bashkatov1, Valery V Tuchin4.   

Abstract

The efficacy of blue light-emitting toothbrushes (B-LETBs) (405 to 420 nm, power density 2  mW/cm(2)) for reduction of dental plaques and gingival inflammation has been evaluated. Microbiological study has shown the multifactor therapeutic action of the B-LETBs on oral pathological microflora: in addition to partial mechanical removal of bacteria, photodynamic action suppresses them up to 97.5%. In the pilot clinical studies, subjects with mild to moderate gingivitis have been randomly divided into two groups: a treatment group that used the B-LETBs and a control group that used standard toothbrushes. Indices of plaque, gingival bleeding, and inflammation have been evaluated. A significant improvement of all dental indices in comparison with the baseline (by 59%, 66%, and 82% for plaque, gingival bleeding, and inflammation, respectively) has been found. The treatment group has demonstrated up to 50% improvement relative to the control group. We have proposed the B-LETBs to serve for prevention of gingivitis or as an alternative to conventional antibiotic treatment of this disease due to their effectiveness and the absence of drug side effects and bacterial resistance.

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Year:  2015        PMID: 26720884     DOI: 10.1117/1.JBO.20.12.128004

Source DB:  PubMed          Journal:  J Biomed Opt        ISSN: 1083-3668            Impact factor:   3.170


  28 in total

1.  Effects on the mitosis of normal and tumor cells induced by light treatment of different wavelengths.

Authors:  R Sroka; M Schaffer; C Fuchs; T Pongratz; U Schrader-Reichard; M Busch; P M Schaffer; E Dühmke; R Baumgartner
Journal:  Lasers Surg Med       Date:  1999       Impact factor: 4.025

2.  PERIODONTAL DISEASE IN PREGNANCY. II. CORRELATION BETWEEN ORAL HYGIENE AND PERIODONTAL CONDTION.

Authors:  J SILNESS; H LOE
Journal:  Acta Odontol Scand       Date:  1964-02       Impact factor: 2.331

3.  Brushing with and without dentifrice on gingival abrasion.

Authors:  P A Versteeg; M F Timmerman; M Piscaer; U Van der Velden; G A Van der Weijden
Journal:  J Clin Periodontol       Date:  2005-02       Impact factor: 8.728

Review 4.  Photodynamic therapy for periodontal diseases: state of the art.

Authors:  Peter Meisel; Thomas Kocher
Journal:  J Photochem Photobiol B       Date:  2005-05-13       Impact factor: 6.252

Review 5.  Photodynamic therapy as an alternative antimicrobial modality for oral infections.

Authors:  Nurgul Komerik; Alexander J MacRobert
Journal:  J Environ Pathol Toxicol Oncol       Date:  2006       Impact factor: 3.567

Review 6.  Periodontal diseases: microbial factors.

Authors:  J J Zambon
Journal:  Ann Periodontol       Date:  1996-11

7.  Phototargeting oral black-pigmented bacteria.

Authors:  Nikolaos S Soukos; Sovanda Som; Abraham D Abernethy; Karriann Ruggiero; Joshua Dunham; Chul Lee; Apostolos G Doukas; J Max Goodson
Journal:  Antimicrob Agents Chemother       Date:  2005-04       Impact factor: 5.191

8.  Phototoxicity of argon laser irradiation on biofilms of Porphyromonas and Prevotella species.

Authors:  C A Henry; B Dyer; M Wagner; M Judy; J L Matthews
Journal:  J Photochem Photobiol B       Date:  1996-07       Impact factor: 6.252

9.  In vivo effect of photodynamic therapy on periodontal bone loss in dental furcations.

Authors:  Juliano Milanezi de Almeida; Leticia Helena Theodoro; Alvaro Francisco Bosco; Maria José Hitomi Nagata; Marie Oshiiwa; Valdir Gouveia Garcia
Journal:  J Periodontol       Date:  2008-06       Impact factor: 6.993

10.  Singlet oxygen (1 delta g) generation from coproporphyrin in Propionibacterium acnes on irradiation.

Authors:  K Arakane; A Ryu; C Hayashi; T Masunaga; K Shinmoto; S Mashiko; T Nagano; M Hirobe
Journal:  Biochem Biophys Res Commun       Date:  1996-06-25       Impact factor: 3.575

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  4 in total

Review 1.  Antimicrobial blue light inactivation of pathogenic microbes: State of the art.

Authors:  Yucheng Wang; Ying Wang; Yuguang Wang; Clinton K Murray; Michael R Hamblin; David C Hooper; Tianhong Dai
Journal:  Drug Resist Updat       Date:  2017-10-13       Impact factor: 18.500

Review 2.  Effect of low power lasers on prokaryotic and eukaryotic cells under different stress condition: a review of the literature.

Authors:  Adenilson de Souza da Fonseca; Larissa Alexsandra da Silva Neto Trajano; Eduardo Tavares Lima Trajano; Flavia de Paoli; Andre Luiz Mencalha
Journal:  Lasers Med Sci       Date:  2021-01-02       Impact factor: 3.161

Review 3.  Recent Patents on Light-Based Anti-Infective Approaches.

Authors:  Imran Ahmed; Yanyan Fang; Min Lu; Quan Yan; Ahmed El-Hussein; Michael R Hamblin; Tianhong Dai
Journal:  Recent Pat Antiinfect Drug Discov       Date:  2018

4.  The effects of violet and blue light irradiation on ESKAPE pathogens and human cells in presence of cell culture media.

Authors:  Richard Bauer; Katharina Hoenes; Tobias Meurle; Martin Hessling; Barbara Spellerberg
Journal:  Sci Rep       Date:  2021-12-28       Impact factor: 4.379

  4 in total

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