Literature DB >> 26705087

Precision Medicine and Rare Genetic Variants.

Volker M Lauschke1, Magnus Ingelman-Sundberg2.   

Abstract

Mesh:

Year:  2015        PMID: 26705087     DOI: 10.1016/j.tips.2015.10.006

Source DB:  PubMed          Journal:  Trends Pharmacol Sci        ISSN: 0165-6147            Impact factor:   14.819


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  21 in total

Review 1.  Novel genetic and epigenetic factors of importance for inter-individual differences in drug disposition, response and toxicity.

Authors:  Volker M Lauschke; Yitian Zhou; Magnus Ingelman-Sundberg
Journal:  Pharmacol Ther       Date:  2019-01-22       Impact factor: 12.310

Review 2.  Sequencing XMET genes to promote genotype-guided risk assessment and precision medicine.

Authors:  Yaqiong Jin; Geng Chen; Wenming Xiao; Huixiao Hong; Joshua Xu; Yongli Guo; Wenzhong Xiao; Tieliu Shi; Leming Shi; Weida Tong; Baitang Ning
Journal:  Sci China Life Sci       Date:  2019-05-20       Impact factor: 6.038

Review 3.  Pharmacogenomic Biomarkers for Improved Drug Therapy-Recent Progress and Future Developments.

Authors:  Volker M Lauschke; Lili Milani; Magnus Ingelman-Sundberg
Journal:  AAPS J       Date:  2017-11-27       Impact factor: 4.009

Review 4.  Assembling the P450 puzzle: on the sources of nonadditivity in drug metabolism.

Authors:  Dmitri R Davydov; Bhagwat Prasad
Journal:  Trends Pharmacol Sci       Date:  2021-09-30       Impact factor: 14.819

5.  CYP2C8, CYP2C9, and CYP2C19 Characterization Using Next-Generation Sequencing and Haplotype Analysis: A GeT-RM Collaborative Project.

Authors:  Andrea Gaedigk; Erin C Boone; Steven E Scherer; Seung-Been Lee; Ibrahim Numanagić; Cenk Sahinalp; Joshua D Smith; Sean McGee; Aparna Radhakrishnan; Xiang Qin; Wendy Y Wang; Emily G Farrow; Nina Gonzaludo; Aaron L Halpern; Deborah A Nickerson; Neil A Miller; Victoria M Pratt; Lisa V Kalman
Journal:  J Mol Diagn       Date:  2022-02-05       Impact factor: 5.341

6.  Novel copy-number variations in pharmacogenes contribute to interindividual differences in drug pharmacokinetics.

Authors:  María Santos; Mikko Niemi; Masahiro Hiratsuka; Masaki Kumondai; Magnus Ingelman-Sundberg; Volker M Lauschke; Cristina Rodríguez-Antona
Journal:  Genet Med       Date:  2017-10-26       Impact factor: 8.822

7.  Pharmacogene Sequencing of a Gabonese Population with Severe Plasmodium falciparum Malaria Reveals Multiple Novel Variants with Putative Relevance for Antimalarial Treatment.

Authors:  Leyre Pernaute-Lau; Ayola Akim Adegnika; Yitian Zhou; Jeannot F Zinsou; Jose Pedro Gil; Sanjeev Krishna; Peter G Kremsner; Volker M Lauschke; Thirumalaisamy P Velavan
Journal:  Antimicrob Agents Chemother       Date:  2021-06-17       Impact factor: 5.191

8.  Probing functional interactions between cytochromes P450 with principal component analysis of substrate saturation profiles and targeted proteomics.

Authors:  Bikash Dangi; Nadezhda Y Davydova; Marc A Maldonado; Deepak Ahire; Bhagwat Prasad; Dmitri R Davydov
Journal:  Arch Biochem Biophys       Date:  2021-05-28       Impact factor: 4.114

Review 9.  Membrane Associated Progesterone Receptors: Promiscuous Proteins with Pleiotropic Functions - Focus on Interactions with Cytochromes P450.

Authors:  Chang S Ryu; Kathrin Klein; Ulrich M Zanger
Journal:  Front Pharmacol       Date:  2017-03-27       Impact factor: 5.810

Review 10.  The Importance of Patient-Specific Factors for Hepatic Drug Response and Toxicity.

Authors:  Volker M Lauschke; Magnus Ingelman-Sundberg
Journal:  Int J Mol Sci       Date:  2016-10-12       Impact factor: 5.923

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