Clinical comparison of a new swept-source optical coherence tomography-based optical biometer and a time-domain optical coherence tomography-based optical biometer.

PURPOSE: To evaluate the repeatability and reproducibility of a newer swept-source optical biometer and to compare it with a standard partial coherence interferometry (PCI) biometer.
SETTING: Siriraj Hospital, Mahidol University, Bangkok, Thailand.
DESIGN: Prospective comparative study.
METHODS: One hundred eyes from 100 cataract patients were enrolled in this study. Each patient was measured with 2 optical biometers, a newer swept-source optical biometer (IOLMaster 700) and a standard partial coherence interferometry biometer (IOLMaster 500) by 2 independent operators. The keratometry, axial length (AL), anterior chamber depth, white-to-white corneal diameter, and intraocular lens (IOL) power, calculated by the SRK/T and the Haigis formulas for each device, were recorded. Intraoperator repeatability and interoperator reproducibility of both devices were analyzed using intraclass correlation coefficients (ICCs). Agreement of ocular biometry and IOL power between the 2 devices was evaluated using the Bland-Altman method.
RESULTS: The repeatability and reproducibility of the swept-source and standard biometers were high for all ocular biometry parameters (ICC, 0.93-1.00). The agreement between the 2 biometers was also high (ICC, 0.92-1.00). The IOL powers obtained from both devices were not distinct. Because of the density of the cataracts, the AL in 5 eyes could be measured only by the swept-source biometer.
CONCLUSIONS: Repeatability and reproducibility of a swept-source optical biometer was excellent and agreement with a standard biometer was very high. Better lens penetration ability and AL measurements were obtained with the swept-source biometer than with the standard biometer. FINANCIAL DISCLOSURE: No author has a financial or proprietary interest in any material or method mentioned.