| Literature DB >> 26695070 |
Julie S Biteen1, Paul C Blainey2, Zoe G Cardon3, Miyoung Chun4, George M Church5, Pieter C Dorrestein, Scott E Fraser6, Jack A Gilbert7,8, Janet K Jansson9, Rob Knight, Jeff F Miller, Aydogan Ozcan, Kimberly A Prather, Stephen R Quake, Edward G Ruby10, Pamela A Silver5, Sharif Taha4, Ger van den Engh11,12, Paul S Weiss, Gerard C L Wong, Aaron T Wright9, Thomas D Young.
Abstract
The microbiome presents great opportunities for understanding and improving the world around us and elucidating the interactions that compose it. The microbiome also poses tremendous challenges for mapping and manipulating the entangled networks of interactions among myriad diverse organisms. Here, we describe the opportunities, technical needs, and potential approaches to address these challenges, based on recent and upcoming advances in measurement and control at the nanoscale and beyond. These technical needs will provide the basis for advancing the largely descriptive studies of the microbiome to the theoretical and mechanistic understandings that will underpin the discipline of microbiome engineering. We anticipate that the new tools and methods developed will also be more broadly useful in environmental monitoring, medicine, forensics, and other areas.Mesh：
Year: 2015 PMID： 26695070 DOI： 10.1021/acsnano.5b07826
Source DB: PubMed Journal: ACS Nano ISSN： 1936-0851 Impact factor: 15.881