BACKGROUND: The Roux-en-Y gastric bypass (GBP) has been considered the gold standard for many years. The loop duodenal switch (LDS) is a relatively new procedure that simplifies the complexity of the duodenal switch (BPDDS) by making it a single anastomosis procedure while at the same time giving it more intestinal absorption to reduce the rates of malnutrition associated with traditional BPDDS. This paper seeks to compare the 18-month weight loss outcomes and complications of the more standard GBP with the newer LDS in a single US center. METHODS: A retrospective matched cohort was analyzed on 108 patients who had either GBP (54 patients) or LDS (54 patients). Regression analysis was used to compare weight loss outcomes as measured by BMI and weight loss percentages. Complications gathered included bleeds, reoperations, diagnostic or therapeutic endoscopy (EGD), ulcers and chronic nausea. RESULTS: GBP and LDS have statistically similar weight loss at 18 months (39.6 vs 41 % weight loss, respectively). However, there were significantly more nausea complaints (26 vs 5), diagnostic endoscopies (EGD) (21 vs 3) and ulcers (6 vs 0) with the GBP than the LDS. CONCLUSION: LDS has comparable weight loss results to GBP. However, LDS has fewer 30-day and 18-month complications and patients suffer from less nausea postoperatively.
BACKGROUND: The Roux-en-Y gastric bypass (GBP) has been considered the gold standard for many years. The loop duodenal switch (LDS) is a relatively new procedure that simplifies the complexity of the duodenal switch (BPDDS) by making it a single anastomosis procedure while at the same time giving it more intestinal absorption to reduce the rates of malnutrition associated with traditional BPDDS. This paper seeks to compare the 18-month weight loss outcomes and complications of the more standard GBP with the newer LDS in a single US center. METHODS: A retrospective matched cohort was analyzed on 108 patients who had either GBP (54 patients) or LDS (54 patients). Regression analysis was used to compare weight loss outcomes as measured by BMI and weight loss percentages. Complications gathered included bleeds, reoperations, diagnostic or therapeutic endoscopy (EGD), ulcers and chronic nausea. RESULTS: GBP and LDS have statistically similar weight loss at 18 months (39.6 vs 41 % weight loss, respectively). However, there were significantly more nausea complaints (26 vs 5), diagnostic endoscopies (EGD) (21 vs 3) and ulcers (6 vs 0) with the GBP than the LDS. CONCLUSION: LDS has comparable weight loss results to GBP. However, LDS has fewer 30-day and 18-month complications and patients suffer from less nausea postoperatively.
Authors: Philip N Okafor; Chueh Lien; Sigrid Bairdain; Donald C Simonson; Florencia Halperin; Ashley H Vernon; Bradley C Linden; David B Lautz Journal: Obes Res Clin Pract Date: 2014-10-18 Impact factor: 2.288
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Authors: Tamer M Nabil; Ahmed H Khalil; Sameh Mikhail; Salah S Soliman; Mostafa Aziz; Halepian Antoine Journal: Obes Surg Date: 2019-10 Impact factor: 4.129
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Authors: Austin Cottam; Daniel Cottam; Dana Portenier; Hinali Zaveri; Amit Surve; Samuel Cottam; Legrand Belnap; Walter Medlin; Christina Richards Journal: Obes Surg Date: 2017-02 Impact factor: 4.129
Authors: Austin Cottam; Daniel Cottam; Mitchell Roslin; Samuel Cottam; Walter Medlin; Christina Richards; Amit Surve; Hinali Zaveri Journal: Obes Surg Date: 2016-10 Impact factor: 4.129