Literature DB >> 26689670

Biosynthesis of polyketides by trans-AT polyketide synthases.

Eric J N Helfrich1, Jörn Piel1.   

Abstract

This review discusses the biosynthesis of natural products that are generated by trans-AT polyketide synthases, a family of catalytically versatile enzymes that represents one of the major group of proteins involved in the production of bioactive polyketides. The article includes 609 references and covers the literature from 2009 through June 2015.

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Year:  2016        PMID： 26689670     DOI： 10.1039/c5np00125k

Source DB:  PubMed          Journal:  Nat Prod Rep        ISSN： 0265-0568            Impact factor:   13.423


  108 in total

1.  Probing the modularity of megasynthases by rational engineering of a fatty acid synthase Type I.

Authors:  Alexander Rittner; Karthik S Paithankar; David Jan Drexler; Aaron Himmler; Martin Grininger
Journal:  Protein Sci       Date:  2018-12-20       Impact factor: 6.725

2.  Mechanism of intersubunit ketosynthase-dehydratase interaction in polyketide synthases.

Authors:  Matthew Jenner; Simone Kosol; Daniel Griffiths; Panward Prasongpholchai; Lucio Manzi; Andrew S Barrow; John E Moses; Neil J Oldham; Józef R Lewandowski; Gregory L Challis
Journal:  Nat Chem Biol       Date:  2018-01-08       Impact factor: 15.040

Review 3.  Oxidative Cyclization in Natural Product Biosynthesis.

Authors:  Man-Cheng Tang; Yi Zou; Kenji Watanabe; Christopher T Walsh; Yi Tang
Journal:  Chem Rev       Date:  2016-12-12       Impact factor: 60.622

Review 4.  The Uncommon Enzymology of Cis-Acyltransferase Assembly Lines.

Authors:  Adrian T Keatinge-Clay
Journal:  Chem Rev       Date:  2017-04-10       Impact factor: 60.622

5.  Employing 25-Residue Docking Motifs from Modular Polyketide Synthases as Orthogonal Protein Connectors.

Authors:  Jessica L Meinke; Anna J Simon; Drew T Wagner; Barrett R Morrow; Shaochen You; Andrew D Ellington; Adrian T Keatinge-Clay
Journal:  ACS Synth Biol       Date:  2019-09-12       Impact factor: 5.110

Review 6.  Natural Products and the Gene Cluster Revolution.

Authors:  Paul R Jensen
Journal:  Trends Microbiol       Date:  2016-08-01       Impact factor: 17.079

7.  Bipartite interactions, antibiotic production and biosynthetic potential of the Arabidopsis leaf microbiome.

Authors:  Eric J N Helfrich; Christine M Vogel; Reiko Ueoka; Martin Schäfer; Florian Ryffel; Daniel B Müller; Silke Probst; Markus Kreuzer; Jörn Piel; Julia A Vorholt
Journal:  Nat Microbiol       Date:  2018-07-23       Impact factor: 17.745

8.  Elucidation of the Stereospecificity of C-Methyltransferases from trans-AT Polyketide Synthases.

Authors:  Xinqiang Xie; Chaitan Khosla; David E Cane
Journal:  J Am Chem Soc       Date:  2017-04-25       Impact factor: 15.419

9.  Extender Unit Promiscuity and Orthogonal Protein Interactions of an Aminomalonyl-ACP Utilizing Trans-Acyltransferase from Zwittermicin Biosynthesis.

Authors:  Samantha M Carpenter; Gavin J Williams
Journal:  ACS Chem Biol       Date:  2018-11-28       Impact factor: 5.100

10.  An Unconventional Melanin Biosynthesis Pathway in Ustilago maydis.

Authors:  Esmeralda Z Reyes-Fernández; Yi-Ming Shi; Peter Grün; Helge B Bode; Michael Bölker
Journal:  Appl Environ Microbiol       Date:  2021-01-15       Impact factor: 4.792
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