Literature DB >> 26643180

Radical-mediated ring contraction in the biosynthesis of 7-deazapurines.

Vahe Bandarian1, Catherine L Drennan2.   

Abstract

Pyrrolopyrimidine containing natural products are widely distributed in Nature. The biosynthesis of the 7-deazapurine moiety that is common to all pyrrolopyrimidines entails multiple steps, one of which is a complex radical-mediated ring contraction reaction catalyzed by CDG synthase. Herein we review the biosynthetic pathways of deazapurines, focusing on the biochemical and structural insights into CDG synthase.
Copyright © 2015 Elsevier Ltd. All rights reserved.

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Year:  2015        PMID： 26643180      PMCID： PMC4753066          DOI： 10.1016/j.sbi.2015.11.005

Source DB:  PubMed          Journal:  Curr Opin Struct Biol        ISSN： 0959-440X            Impact factor:   6.809


  43 in total

1.  Isolation and characterization of a guanine insertion enzyme, a specific tRNA transglycosylase, from Escherichia coli.

Authors:  N Okada; S Nishimura
Journal:  J Biol Chem       Date:  1979-04-25       Impact factor: 5.157

2.  THE BIOSYNTHESIS OF FOLIC ACID. IV. ENZYMATIC SYNTHESIS OF DIHYDROFOLIC ACID FROM GUANINE AND RIBOSE COMPOUNDS.

Authors:  J J REYNOLDS; G M BROWN
Journal:  J Biol Chem       Date:  1964-01       Impact factor: 5.157

3.  Possible anticodon sequences of tRNA His , tRNA Asm , and tRNA Asp from Escherichia coli B. Universal presence of nucleoside Q in the first postion of the anticondons of these transfer ribonucleic acids.

Authors:  F Harada; S Nishimura
Journal:  Biochemistry       Date:  1972-01-18       Impact factor: 3.162

4.  Purification of 6-pyruvoyl-tetrahydropterin synthase from human liver.

Authors:  S Takikawa; H C Curtius; U Redweik; S Ghisla
Journal:  Biochem Biophys Res Commun       Date:  1986-01-29       Impact factor: 3.575

5.  Structure of the modified nucleoside Q isolated from Escherichia coli transfer ribonucleic acid. 7-(4,5-cis-Dihydroxy-1-cyclopenten-3-ylaminomethyl)-7-deazaguanosine.

Authors:  H Kasai; Z Oashi; F Harada; S Nishimura; N J Oppenheimer; P F Crain; J G Liehr; D L von Minden; J A McCloskey
Journal:  Biochemistry       Date:  1975-09-23       Impact factor: 3.162

6.  Purification and properties of guanosine triphosphate cyclohydrolase II from Escherichia coli.

Authors:  F Foor; G M Brown
Journal:  J Biol Chem       Date:  1975-05-10       Impact factor: 5.157

7.  Biosynthesis of the modified nucleoside Q in transfer RNA.

Authors:  Y Kuchino; H Kasai; K Nihei; S Nishimura
Journal:  Nucleic Acids Res       Date:  1976-02       Impact factor: 16.971

8.  Novel mechanism of post-transcriptional modification of tRNA. Insertion of bases of Q precursors into tRNA by a specific tRNA transglycosylase reaction.

Authors:  N Okada; S Noguchi; H Kasai; N Shindo-Okada; T Ohgi; T Goto; S Nishimura
Journal:  J Biol Chem       Date:  1979-04-25       Impact factor: 5.157

9.  A new function of S-adenosylmethionine: the ribosyl moiety of AdoMet is the precursor of the cyclopentenediol moiety of the tRNA wobble base queuine.

Authors:  R K Slany; M Bösl; P F Crain; H Kersten
Journal:  Biochemistry       Date:  1993-08-03       Impact factor: 3.162

10.  Biosynthesis of the pyrrolopyrimidine nucleoside antibiotic, toyocamycin. VII. Origin of the pyrrole carbons and the cyano carbon.

Authors:  R J Suhadolnik; T Uematsu
Journal:  J Biol Chem       Date:  1970-09-10       Impact factor: 5.157
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  5 in total

1.  Radical Reaction Control in the AdoMet Radical Enzyme CDG Synthase (QueE): Consolidate, Destabilize, Accelerate.

Authors:  Christof M Jäger; Anna K Croft
Journal:  Chemistry       Date:  2016-12-13       Impact factor: 5.236

2.  Biochemical and Structural Characterization of a Schiff Base in the Radical-Mediated Biosynthesis of 4-Demethylwyosine by TYW1.

Authors:  Tsehai A J Grell; Anthony P Young; Catherine L Drennan; Vahe Bandarian
Journal:  J Am Chem Soc       Date:  2018-05-24       Impact factor: 15.419

3.  Discovery and characterization of the tubercidin biosynthetic pathway from Streptomyces tubercidicus NBRC 13090.

Authors:  Yan Liu; Rong Gong; Xiaoqin Liu; Peichao Zhang; Qi Zhang; You-Sheng Cai; Zixin Deng; Margit Winkler; Jianguo Wu; Wenqing Chen
Journal:  Microb Cell Fact       Date:  2018-08-28       Impact factor: 5.328

4.  Analysis of Electrochemical Properties of S-Adenosyl-l-methionine and Implications for Its Role in Radical SAM Enzymes.

Authors:  Sven A Miller; Vahe Bandarian
Journal:  J Am Chem Soc       Date:  2019-07-08       Impact factor: 15.419

Review 5.  Deazaguanine derivatives, examples of crosstalk between RNA and DNA modification pathways.

Authors:  Geoffrey Hutinet; Manal A Swarjo; Valérie de Crécy-Lagard
Journal:  RNA Biol       Date:  2016-12-12       Impact factor: 4.652
  5 in total

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