Literature DB >> 26637472

Georgia Primary Care Providers' Knowledge of Hereditary Breast and Ovarian Cancer Syndrome.

Navya Nair1, Cecelia Bellcross2, Lisa Haddad3, Monique Martin4, Roland Matthews5, Sheryl Gabram-Mendola6, Barbara Crane4, Dana Meaney-Delman3.   

Abstract

Hereditary breast and ovarian cancer syndrome (HBOC) is an inherited condition associated with mutations in the BRCA1 or BRCA2 (BRCA) genes. Identification of individuals with HBOC requires that primary care providers understand the genetic principles required to appropriately collect family history and refer individuals for genetic evaluation. A survey was developed and administered to primary care providers in Georgia to assess their existing knowledge of HBOC and direct targeted educational efforts.We found that Georgia providers demonstrate some knowledge of basic genetic principles but were unable to consistently identify individuals at risk for HBOC. Knowledge deficits included lack of understanding of inheritance patterns and failure to recognize the significance of ovarian cancer history. Strategies for improving identification of patients with HBOC include increasing provider knowledge and integrating HBOC risk assessment tools into practice. Identification of individuals at risk is the critical first step in the process of reducing incidence of breast and ovarian cancer associated with BRCA mutations.

Entities:  

Keywords:  BRCA; Breast cancer; Hereditary; Ovarian cancer

Mesh:

Year:  2017        PMID: 26637472     DOI: 10.1007/s13187-015-0950-9

Source DB:  PubMed          Journal:  J Cancer Educ        ISSN: 0885-8195            Impact factor:   2.037


  23 in total

1.  Mammography, breast ultrasound, and magnetic resonance imaging for surveillance of women at high familial risk for breast cancer.

Authors:  Christiane K Kuhl; Simone Schrading; Claudia C Leutner; Nuschin Morakkabati-Spitz; Eva Wardelmann; Rolf Fimmers; Walther Kuhn; Hans H Schild
Journal:  J Clin Oncol       Date:  2005-11-20       Impact factor: 44.544

2.  Physician Risk Assessment Knowledge Regarding BRCA Genetics Testing.

Authors:  Jason Cohn; William Blazey; David Tegay; Brian Harper; Sharon Koehler; Brookshield Laurent; Vivian Chan; Min-Kyung Jung; Bhuma Krishnamachari
Journal:  J Cancer Educ       Date:  2015-09       Impact factor: 2.037

3.  Breast cancer after prophylactic bilateral mastectomy in women with a BRCA1 or BRCA2 mutation.

Authors:  H Meijers-Heijboer; B van Geel; W L van Putten; S C Henzen-Logmans; C Seynaeve; M B Menke-Pluymers; C C Bartels; L C Verhoog; A M van den Ouweland; M F Niermeijer; C T Brekelmans; J G Klijn
Journal:  N Engl J Med       Date:  2001-07-19       Impact factor: 91.245

4.  Association of risk-reducing surgery in BRCA1 or BRCA2 mutation carriers with cancer risk and mortality.

Authors:  Susan M Domchek; Tara M Friebel; Christian F Singer; D Gareth Evans; Henry T Lynch; Claudine Isaacs; Judy E Garber; Susan L Neuhausen; Ellen Matloff; Rosalind Eeles; Gabriella Pichert; Laura Van t'veer; Nadine Tung; Jeffrey N Weitzel; Fergus J Couch; Wendy S Rubinstein; Patricia A Ganz; Mary B Daly; Olufunmilayo I Olopade; Gail Tomlinson; Joellen Schildkraut; Joanne L Blum; Timothy R Rebbeck
Journal:  JAMA       Date:  2010-09-01       Impact factor: 56.272

5.  Reported referral for genetic counseling or BRCA 1/2 testing among United States physicians: a vignette-based study.

Authors:  Katrina F Trivers; Laura-Mae Baldwin; Jacqueline W Miller; Barbara Matthews; C Holly A Andrilla; Denise M Lishner; Barbara A Goff
Journal:  Cancer       Date:  2011-07-25       Impact factor: 6.860

6.  Breast cancer risk following bilateral oophorectomy in BRCA1 and BRCA2 mutation carriers: an international case-control study.

Authors:  Andrea Eisen; Jan Lubinski; Jan Klijn; Pal Moller; Henry T Lynch; Kenneth Offit; Barbara Weber; Tim Rebbeck; Susan L Neuhausen; Parviz Ghadirian; William D Foulkes; Ruth Gershoni-Baruch; Eitan Friedman; Gadi Rennert; Teresa Wagner; Claudine Isaacs; Charmaine Kim-Sing; Peter Ainsworth; Ping Sun; Steven A Narod
Journal:  J Clin Oncol       Date:  2005-10-20       Impact factor: 44.544

Review 7.  Genetic testing by cancer site: ovary.

Authors:  Scott M Weissman; Shelly M Weiss; Anna C Newlin
Journal:  Cancer J       Date:  2012 Jul-Aug       Impact factor: 3.360

8.  Risk assessment, genetic counseling, and genetic testing for BRCA-related cancer in women: U.S. Preventive Services Task Force recommendation statement.

Authors:  Virginia A Moyer
Journal:  Ann Intern Med       Date:  2014-02-18       Impact factor: 25.391

9.  Genetic/familial high-risk assessment: breast and ovarian, version 1.2014.

Authors:  Mary B Daly; Robert Pilarski; Jennifer E Axilbund; Saundra S Buys; Beth Crawford; Susan Friedman; Judy E Garber; Carolyn Horton; Virginia Kaklamani; Catherine Klein; Wendy Kohlmann; Allison Kurian; Jennifer Litton; Lisa Madlensky; P Kelly Marcom; Sofia D Merajver; Kenneth Offit; Tuya Pal; Boris Pasche; Gwen Reiser; Kristen Mahoney Shannon; Elizabeth Swisher; Nicoleta C Voian; Jeffrey N Weitzel; Alison Whelan; Georgia L Wiesner; Mary A Dwyer; Rashmi Kumar
Journal:  J Natl Compr Canc Netw       Date:  2014-09       Impact factor: 11.908

10.  NSGC practice guideline: risk assessment and genetic counseling for hereditary breast and ovarian cancer.

Authors:  Janice L Berliner; Angela Musial Fay; Shelly A Cummings; Brittany Burnett; Todd Tillmanns
Journal:  J Genet Couns       Date:  2012-11-28       Impact factor: 2.537

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  9 in total

1.  Women with Family History of Breast Cancer: How Much Are They Aware of Their Risk?

Authors:  Memnun Seven; Gülcan Bağcivan; Aygul Akyuz; Ferdağ Bölükbaş
Journal:  J Cancer Educ       Date:  2018-08       Impact factor: 2.037

2.  An Applied Framework in Support of Shared Decision Making about BRCA Genetic Testing.

Authors:  Thomas B Silverman; Gilad J Kuperman; Alejandro Vanegas; Margaret Sin; Jill Dimond; Katherine D Crew; Rita Kukafka
Journal:  AMIA Annu Symp Proc       Date:  2018-12-05

Review 3.  Primary care providers' cancer genetic testing-related knowledge, attitudes, and communication behaviors: A systematic review and research agenda.

Authors:  Jada G Hamilton; Ekland Abdiwahab; Heather M Edwards; Min-Lin Fang; Andrew Jdayani; Erica S Breslau
Journal:  J Gen Intern Med       Date:  2016-12-19       Impact factor: 5.128

Review 4.  Experiences of individuals with a variant of uncertain significance on genetic testing for hereditary cancer risks: a mixed method systematic review.

Authors:  Danielle Gould; Rachel Walker; Grace Makari-Judson; Memnun Seven
Journal:  J Community Genet       Date:  2022-07-12

5.  Provider discussion of genetic counseling among high-risk Spanish-preferring Latina breast cancer survivors.

Authors:  Claire C Conley; Jessica N Rivera Rivera; Eida M Castro-Figueroa; Laura Moreno; Julie Dutil; Jennifer D García; Charité Ricker; Gwendolyn P Quinn; Hatem Soliman; Susan T Vadaparampil
Journal:  Transl Behav Med       Date:  2022-10-07       Impact factor: 3.626

6.  Creation and Implementation of an Environmental Scan to Assess Cancer Genetics Services at Three Oncology Care Settings.

Authors:  Erica M Bednar; Michael T Walsh; Ellen Baker; Kimberly I Muse; Holly D Oakley; Rebekah C Krukenberg; Cara S Dresbold; Sandra B Jenkinson; Amanda L Eppolito; Kelly B Teed; Molly H Klein; Nichole A Morman; Elizabeth C Bowdish; Pauline Russ; Emaline E Wise; Julia N Cooper; Michael W Method; John W Henson; Andrew V Grainger; Banu K Arun; Karen H Lu
Journal:  J Genet Couns       Date:  2018-05-16       Impact factor: 2.537

7.  Patient and Clinician Decision Support to Increase Genetic Counseling for Hereditary Breast and Ovarian Cancer Syndrome in Primary Care: A Cluster Randomized Clinical Trial.

Authors:  Rita Kukafka; Samuel Pan; Thomas Silverman; Tianmai Zhang; Wendy K Chung; Mary Beth Terry; Elaine Fleck; Richard G Younge; Meghna S Trivedi; Julia E McGuinness; Ting He; Jill Dimond; Katherine D Crew
Journal:  JAMA Netw Open       Date:  2022-07-01

8.  Study protocol: a cluster randomized controlled trial of web-based decision support tools for increasing BRCA1/2 genetic counseling referral in primary care.

Authors:  Thomas B Silverman; Alejandro Vanegas; Awilda Marte; Jennie Mata; Margaret Sin; Juan Carlos Rodriguez Ramirez; Wei-Yann Tsai; Katherine D Crew; Rita Kukafka
Journal:  BMC Health Serv Res       Date:  2018-08-13       Impact factor: 2.655

9.  Comparison of up-front cash cards and checks as incentives for participation in a clinician survey: a study within a trial.

Authors:  Lydia E Pace; Yeonsoo S Lee; Nadine Tung; Jada G Hamilton; Camila Gabriel; Sahitya C Raja; Colby Jenkins; Anthony Braswell; Susan M Domchek; Heather Symecko; Kelsey Spielman; Beth Y Karlan; Jenny Lester; Daniella Kamara; Jeffrey Levin; Kelly Morgan; Kenneth Offit; Judy Garber; Nancy L Keating
Journal:  BMC Med Res Methodol       Date:  2020-08-17       Impact factor: 4.615

  9 in total

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