Literature DB >> 25234477

Physician Risk Assessment Knowledge Regarding BRCA Genetics Testing.

Jason Cohn1, William Blazey, David Tegay, Brian Harper, Sharon Koehler, Brookshield Laurent, Vivian Chan, Min-Kyung Jung, Bhuma Krishnamachari.   

Abstract

The study aim was to evaluate the association between genetics referrals, training in medical school, residency, or continuing medical education and physician knowledge of hereditary breast and ovarian cancer (HBOC). A survey of 55 questions was administered to 140 physicians evaluating knowledge and practice patterns regarding HBOC. Physicians with genetics training during residency were more likely to recognize that most instances of ovarian cancer are not hereditary (odds ratio (OR) = 3.16; 95 % confidence interval (CI) 1.32, 7.58). Physicians with continuing medical education (CME) training on genetics were more likely to identify that screening can be improved for those with a hereditary mutation (OR = 4.28; 95 % CI 1.32, 13.90). Primary care physicians who frequently referred for genetics were more likely to recognize that maternal history is not more important than paternal history (OR = 2.51; 95 % CI 1.11, 5.66), that screening can be improved for those with hereditary risk (OR = 4.06; 95 % CI 1.08, 15.22), and that females with a hereditary breast cancer risk would have different recommendations for screening than someone without this risk (OR = 4.91; 95 % CI 1.04, 23.25). Our data suggest that training and frequency of genetics referrals may be associated with knowledge of general risk assessment for HBOC.

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Year:  2015        PMID: 25234477     DOI: 10.1007/s13187-014-0724-9

Source DB:  PubMed          Journal:  J Cancer Educ        ISSN: 0885-8195            Impact factor:   2.037


  23 in total

1.  Physician exposure to and attitudes toward advertisements for genetic tests for inherited cancer susceptibility.

Authors:  Susan Thomas Vadaparampil; Louise Wideroff; Lorayn Olson; K Viswanath; Andrew N Freedman
Journal:  Am J Med Genet A       Date:  2005-05-15       Impact factor: 2.802

2.  Hereditary breast/ovarian and colorectal cancer genetics knowledge in a national sample of US physicians.

Authors:  L Wideroff; S T Vadaparampil; M H Greene; S Taplin; L Olson; A N Freedman
Journal:  J Med Genet       Date:  2005-03-22       Impact factor: 6.318

3.  Significant differences among physician specialties in management recommendations of BRCA1 mutation carriers.

Authors:  S U Dhar; H P Cooper; T Wang; B Parks; S A Staggs; S Hilsenbeck; S E Plon
Journal:  Breast Cancer Res Treat       Date:  2011-04-05       Impact factor: 4.872

4.  Genetic services for familial cancer patients: a follow-up survey of National Cancer Institute Cancer Centers.

Authors:  Meira Epplein; Ksenia P Koon; Scott D Ramsey; John D Potter
Journal:  J Clin Oncol       Date:  2005-07-20       Impact factor: 44.544

5.  Assessing breast cancer risk and providing treatment recommendations: immediate impact of an educational session.

Authors:  Sheryl G A Gabram; Teri Dougherty; Kathy S Albain; Kimberly Klein; Patricia Mumby; Kit Lee; Kathy Yao; Bhuma Krishnamachari; Catheryn J Salibay; Mary Jo Lund
Journal:  Breast J       Date:  2009 Sep-Oct       Impact factor: 2.431

6.  Risk assessment, genetic counseling, and genetic testing for BRCA-related cancer in women: U.S. Preventive Services Task Force recommendation statement.

Authors:  Virginia A Moyer
Journal:  Ann Intern Med       Date:  2014-02-18       Impact factor: 25.391

7.  Cancer statistics, 2013.

Authors:  Rebecca Siegel; Deepa Naishadham; Ahmedin Jemal
Journal:  CA Cancer J Clin       Date:  2013-01-17       Impact factor: 508.702

8.  Efficacy of MRI and mammography for breast-cancer screening in women with a familial or genetic predisposition.

Authors:  Mieke Kriege; Cecile T M Brekelmans; Carla Boetes; Peter E Besnard; Harmine M Zonderland; Inge Marie Obdeijn; Radu A Manoliu; Theo Kok; Hans Peterse; Madeleine M A Tilanus-Linthorst; Sara H Muller; Sybren Meijer; Jan C Oosterwijk; Louk V A M Beex; Rob A E M Tollenaar; Harry J de Koning; Emiel J T Rutgers; Jan G M Klijn
Journal:  N Engl J Med       Date:  2004-07-29       Impact factor: 91.245

Review 9.  Efficacy of risk-reducing salpingo-oophorectomy in women with BRCA-1 and BRCA-2 mutations.

Authors:  Olufunmilayo I Olopade; Grazia Artioli
Journal:  Breast J       Date:  2004 Jan-Feb       Impact factor: 2.431

10.  Personalized cancer genetics training for personalized medicine: improving community-based healthcare through a genetically literate workforce.

Authors:  Kathleen R Blazer; Deborah J Macdonald; Julie O Culver; Carin R Huizenga; Robert J Morgan; Gwen C Uman; Jeffrey N Weitzel
Journal:  Genet Med       Date:  2011-09       Impact factor: 8.822

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  4 in total

1.  Factors Associated with Interest in Gene-Panel Testing and Risk Communication Preferences in Women from BRCA1/2 Negative Families.

Authors:  Kristina G Flores; Laurie E Steffen; Christopher J McLouth; Belinda E Vicuña; Amanda Gammon; Wendy Kohlmann; Lucretia Vigil; Zoneddy R Dayao; Melanie E Royce; Anita Y Kinney
Journal:  J Genet Couns       Date:  2016-08-06       Impact factor: 2.537

Review 2.  Primary care providers' cancer genetic testing-related knowledge, attitudes, and communication behaviors: A systematic review and research agenda.

Authors:  Jada G Hamilton; Ekland Abdiwahab; Heather M Edwards; Min-Lin Fang; Andrew Jdayani; Erica S Breslau
Journal:  J Gen Intern Med       Date:  2016-12-19       Impact factor: 5.128

3.  Georgia Primary Care Providers' Knowledge of Hereditary Breast and Ovarian Cancer Syndrome.

Authors:  Navya Nair; Cecelia Bellcross; Lisa Haddad; Monique Martin; Roland Matthews; Sheryl Gabram-Mendola; Barbara Crane; Dana Meaney-Delman
Journal:  J Cancer Educ       Date:  2017-03       Impact factor: 2.037

4.  Health care professionals' attitudes towards population-based genetic testing and risk-stratification for ovarian cancer: a cross-sectional survey.

Authors:  Katie E J Hann; Lindsay Fraser; Lucy Side; Sue Gessler; Jo Waller; Saskia C Sanderson; Madeleine Freeman; Ian Jacobs; Anne Lanceley
Journal:  BMC Womens Health       Date:  2017-12-16       Impact factor: 2.809

  4 in total

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