Literature DB >> 26631768

Robotic Versus Laparoscopic Radical Trachelectomy for Early-Stage Cervical Cancer: Case Report and Review of Literature.

Murat Api1, Aysen Boza2, Mehmet Ceyhan1.   

Abstract

We conducted a literature review to evaluate the minimally invasive fertility-sparing procedures, namely robotic radical trachelectomy (RRT) and laparoscopic radical trachelectomy (LRT), in patients with early-stage cervical cancer. We searched PubMed, MEDLINE, Ovid, Google Scholar, and Scopus up to July 2015 using the following key words and their combinations: cervical cancer, early stage, fertility-sparing surgery, radical trachelectomy, robotic trachelectomy, and laparoscopic trachelectomy. Papers providing details of RRT and LRT separately were included. Extracted papers and their bibliographies were reviewed according to the purpose of the study, and demographic, surgical, and clinical parameters were analyzed. Our review comprised 45 cases of RRT and 216 cases (including our case) of LRT. The median (range) patient age was 29 (9) years in the RRT group and 32 (10) years in the LRT group (p < .001). Histological types and stages were significantly different in the 2 groups (p < .001 for both). The median length of excised parametrial tissue was significantly higher in the RRT group (p < .001). The hysterectomy conversion rate on the results of frozen section examination was significantly higher in the RRT group (37% vs 6.5%; p < .001). There was a significant difference in median lymph node count based on the surgical approach (RRT: 22 [range, 21] vs LRT: 32 [range, 14]; p = .02). Estimated blood loss and length of hospital stay were significantly higher in the LRT group (both p < .001). The mean (range) operative time was 308 (188) minutes in the RRT group and 296 (143) minutes in the LRT group (p < .001). Pregnancy, preterm, and term birth rates were similar in the 2 groups (RRT: 18.5%, 7.4%, and 0, respectively; LRT: 29%, 8%, and 8%, respectively). Thirteen women experienced recurrent cervical cancer in the LRT group, and no recurrence was seen in the RRT group. The median (range) duration of follow-up was 8 (7.5) months in the RRT group and 34 (20) months in the LRT group (p < .001). Based on the reported data, LRT seems comparable to RRT for treating patients with early-stage cervical cancer who wish to preserve fertility.
Copyright © 2016 AAGL. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Cervical cancer; Fertility; Laparoscopy; Radical trachelectomy; Robotic

Mesh:

Year:  2015        PMID: 26631768     DOI: 10.1016/j.jmig.2015.11.009

Source DB:  PubMed          Journal:  J Minim Invasive Gynecol        ISSN: 1553-4650            Impact factor:   4.137


  4 in total

1.  Quality of life after radical trachelectomy for early-stage cervical cancer: A 5-year prospective evaluation.

Authors:  N D Fleming; P T Ramirez; P T Soliman; K M Schmeler; G B Chisholm; A M Nick; S N Westin; M Frumovitz
Journal:  Gynecol Oncol       Date:  2016-10-11       Impact factor: 5.482

Review 2.  Current state of fertility preservation for adolescent and young adult patients with gynecological cancer.

Authors:  Tatsuru Ohara; Shiho Kuji; Tomo Takenaga; Haruka Imai; Hiraku Endo; Ryo Kanamori; Jun Takeuchi; Yuko Nagasawa; Noriyuki Yokomichi; Haruhiro Kondo; Imari Deura; Akiko Tozawa; Nao Suzuki
Journal:  Int J Clin Oncol       Date:  2021-11-15       Impact factor: 3.402

3.  Safety evaluation of abdominal trachelectomy in patients with cervical tumors ≥2 cm: a single-institution, retrospective analysis.

Authors:  Kaoru Okugawa; Hideaki Yahata; Kenzo Sonoda; Tatsuhiro Ohgami; Masafumi Yasunaga; Eisuke Kaneki; Kiyoko Kato
Journal:  J Gynecol Oncol       Date:  2019-12-18       Impact factor: 4.401

Review 4.  Robotics in reproduction, fertility preservation, and ovarian transplantation.

Authors:  Enes Taylan; Kutluk H Oktay
Journal:  Robot Surg       Date:  2017-02-27
  4 in total

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