Liquan Dong1, Zidong Bie2, Liye Sun3, Xudong Pan3, Lijuan Guo4. 1. Qingdao University Shandong, P. R. China. 2. Department of Cardiovascular Medicine, Weihai Wendeng Center Hospital Shandong, P. R. China ; Medical College of Shandong University Shandong, P. R. China. 3. Affiliated Hospital of Qingdao University Shandong, P. R. China. 4. Department of Cardiovascular Medicine, Weihai Wendeng Center Hospital Shandong, P. R. China.
Abstract
BACKGROUND: Catheter ablation of atrial fibrillation (AF) became an effective therapy for patients with drug-refractory AF and Catheter ablation of Non-Paroxysmal AF for elderly remains a challenging task. The outcome of AF ablation in Elderly is not clear. OBJECTIVE: The aim of the present study was to investigate the long-term outcomes of catheter ablation in patients with non-paroxysmal AF and the predictors of AF termination, and the clinical outcomes associated with termination and non-termination. METHODS: A total of 95 non-paroxysmal AF patients who received a stepwise catheter ablation were enrolled. There were 46 patients (48.4%) suffering from recurrences (37 patients with AF and 9 patients with atrial flutter/atrial tachycardia) after single procedure during a median follow-up period of 25.6 months. AF termination by ablation was achieved in 73 of the 95 patients RESULTS: The AF non-termination after procedure and CHA2DS2-VASc scores ≥3 were significant predictors of recurrences in the multivariable analysis. In AF termination group: for a CHA2DS2-VASc scores of 0, 1-2, and ≥3 the recurrence rates were 29% (8/28), 39% (12/31) and 64% (9/14) respectively. Similarly, In AF non-termination group: for a CHA2DS2-VASc scores of 0, 1-2, and ≥3 the recurrence rates were 63% (5/8), 75% (6/8), and 100% (6/6), respectively. Of the patients with CHA2DS2-VASc scores of ≥3 in AF non-termination group all experienced recurrences within 2 year after the single procedure. CONCLUSIONS: The catheter ablation may be effective in eliminating part of non-paroxysmal AF for elderly. In addition, the present study demonstrated that CHA2DS2-VASc scores and non-termination after procedure were useful predictors of AF recurrence.
BACKGROUND: Catheter ablation of atrial fibrillation (AF) became an effective therapy for patients with drug-refractory AF and Catheter ablation of Non-Paroxysmal AF for elderly remains a challenging task. The outcome of AF ablation in Elderly is not clear. OBJECTIVE: The aim of the present study was to investigate the long-term outcomes of catheter ablation in patients with non-paroxysmal AF and the predictors of AF termination, and the clinical outcomes associated with termination and non-termination. METHODS: A total of 95 non-paroxysmal AFpatients who received a stepwise catheter ablation were enrolled. There were 46 patients (48.4%) suffering from recurrences (37 patients with AF and 9 patients with atrial flutter/atrial tachycardia) after single procedure during a median follow-up period of 25.6 months. AF termination by ablation was achieved in 73 of the 95 patients RESULTS: The AF non-termination after procedure and CHA2DS2-VASc scores ≥3 were significant predictors of recurrences in the multivariable analysis. In AF termination group: for a CHA2DS2-VASc scores of 0, 1-2, and ≥3 the recurrence rates were 29% (8/28), 39% (12/31) and 64% (9/14) respectively. Similarly, In AF non-termination group: for a CHA2DS2-VASc scores of 0, 1-2, and ≥3 the recurrence rates were 63% (5/8), 75% (6/8), and 100% (6/6), respectively. Of the patients with CHA2DS2-VASc scores of ≥3 in AF non-termination group all experienced recurrences within 2 year after the single procedure. CONCLUSIONS: The catheter ablation may be effective in eliminating part of non-paroxysmal AF for elderly. In addition, the present study demonstrated that CHA2DS2-VASc scores and non-termination after procedure were useful predictors of AF recurrence.
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