Literature DB >> 26602534

Restrictive blood transfusion protocol in malignant upper gastrointestinal and pancreatic resections patients reduces blood transfusions with no increase in patient morbidity.

John Wehry1, Steven Agle1, Prejesh Philips1, Robert Cannon1, Charles R Scoggins1, Lisa Puffer1, Kelly M McMasters1, Robert C G Martin2.   

Abstract

BACKGROUND: The purpose of this study was to determine the impact of a restrictive blood transfusion protocol on the number of transfusions performed and the related effect on patient morbidity.
METHODS: A cohort study was performed using our prospective database with information from January 1, 2000, to June 1, 2013. The restrictive blood transfusion protocol was implemented in September 2011, so this date served as the separation point for the date of operation criteria.
RESULTS: For the study, 415 patients undergoing operation for an abdominal malignancy were reviewed. After the restrictive blood transfusion protocol, the percentage of patients who received blood dropped from 35.6% to 28.3%. The percentage of patients who experienced perioperative complication was significantly higher in transfused patients compared with those who did not receive blood (P = .0001). There was no statistical significance observed between the 5 groups for the length of stay at the hospital after their procedure.
CONCLUSIONS: The restrictive blood transfusion protocol resulted in a reduction of the percentage of patients transfused, and there was no evidence to suggest that it negatively affected the outcomes of patients in this group.
Copyright © 2015 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Blood transfusion; Complications; Esophagectomy; Gastrectomy; Hepatectomy; Pancreatectomy

Mesh:

Year:  2015        PMID: 26602534      PMCID: PMC4743748          DOI: 10.1016/j.amjsurg.2015.08.013

Source DB:  PubMed          Journal:  Am J Surg        ISSN: 0002-9610            Impact factor:   2.565


  21 in total

1.  Transfusion of allogenic leukocyte-depleted packed red blood cells is associated with postoperative morbidity in patients undergoing oral and oropharyngeal cancer surgery.

Authors:  Christos Perisanidis; Markus Dettke; Nikolaos Papadogeorgakis; Alexandra Schoppmann; Martina Mittlböck; Panayiotis A Kyzas; Rolf Ewers; Rudolf Seemann
Journal:  Oral Oncol       Date:  2011-12-17       Impact factor: 5.337

2.  Advantage of autologous blood transfusion in surgery for hepatocellular carcinoma.

Authors:  Yoshito Tomimaru; Hidetoshi Eguchi; Shigeru Marubashi; Hiroshi Wada; Shogo Kobayashi; Masahiro Tanemura; Koji Umeshita; Yuichiro Doki; Masaki Mori; Hiroaki Nagano
Journal:  World J Gastroenterol       Date:  2011-08-28       Impact factor: 5.742

3.  Operative blood loss, blood transfusion, and 30-day mortality in older patients after major noncardiac surgery.

Authors:  Wen-Chih Wu; Tracy S Smith; William G Henderson; Charles B Eaton; Roy M Poses; Georgette Uttley; Vincent Mor; Satish C Sharma; Michael Vezeridis; Shukri F Khuri; Peter D Friedmann
Journal:  Ann Surg       Date:  2010-07       Impact factor: 12.969

Review 4.  Transfusion-related mortality: the ongoing risks of allogeneic blood transfusion and the available strategies for their prevention.

Authors:  Eleftherios C Vamvakas; Morris A Blajchman
Journal:  Blood       Date:  2009-02-02       Impact factor: 22.113

5.  Randomized clinical trial of preoperative intravenous iron sucrose to reduce blood transfusion in anaemic patients after colorectal cancer surgery.

Authors:  T J Edwards; E J Noble; A Durran; N Mellor; K B Hosie
Journal:  Br J Surg       Date:  2009-10       Impact factor: 6.939

Review 6.  Transfusion-related immunomodulation (TRIM): an update.

Authors:  Eleftherios C Vamvakas; Morris A Blajchman
Journal:  Blood Rev       Date:  2007-09-04       Impact factor: 8.250

Review 7.  Cancer-related anemia: pathogenesis, prevalence and treatment.

Authors:  Gunnar Birgegård; Matti S Aapro; Carsten Bokemeyer; Mario Dicato; Peter Drings; Javier Hornedo; Maciej Krzakowski; Heinz Ludwig; Sergio Pecorelli; Hans Schmoll; Maurice Schneider; Dirk Schrijvers; Daniel Shasha; Simon Van Belle
Journal:  Oncology       Date:  2005       Impact factor: 2.935

8.  Predicting the risk of perioperative transfusion for patients undergoing elective hepatectomy.

Authors:  Camelia S Sima; William R Jarnagin; Yuman Fong; Elena Elkin; Mary Fischer; David Wuest; Michael D'Angelica; Ronald P DeMatteo; Leslie H Blumgart; Mithat Gönen
Journal:  Ann Surg       Date:  2009-12       Impact factor: 12.969

Review 9.  Safety and efficacy of intravenous iron therapy in reducing requirement for allogeneic blood transfusion: systematic review and meta-analysis of randomised clinical trials.

Authors:  Edward Litton; Jing Xiao; Kwok M Ho
Journal:  BMJ       Date:  2013-08-15

10.  Appropriateness of perioperative blood transfusion in patients undergoing cancer surgery: A prospective single-centre study.

Authors:  Priya Ranganathan; Sarfaraz Ahmed; Atul P Kulkarni; Jigeeshu V Divatia
Journal:  Indian J Anaesth       Date:  2012-05
View more
  6 in total

Review 1.  Laparoscopic pancreatoduodenectomy: current status and future directions.

Authors:  Alessandro Coppola; John A Stauffer; Horacio J Asbun
Journal:  Updates Surg       Date:  2016-11-04

Review 2.  How low should we go: A systematic review and meta-analysis of the impact of restrictive red blood cell transfusion strategies in oncology.

Authors:  Lauren S Prescott; Jolyn S Taylor; Maria A Lopez-Olivo; Mark F Munsell; Helena M VonVille; David R Lairson; Diane C Bodurka
Journal:  Cancer Treat Rev       Date:  2016-03-28       Impact factor: 12.111

3.  The impact of perioperative blood transfusions on short-term outcomes following hepatectomy.

Authors:  Julie Hallet; Alyson L Mahar; Avery B Nathens; Melanie E Tsang; Kaitlyn A Beyfuss; Yulia Lin; Natalie G Coburn; Paul J Karanicolas
Journal:  Hepatobiliary Surg Nutr       Date:  2018-02       Impact factor: 7.293

4.  Operating on Jehovah's Witnesses: A Challenging Surgical Issue.

Authors:  Zoe Garoufalia; Apostolos Aggelis; Efstathios A Antoniou; Gregory Kouraklis; Costantine Vagianos
Journal:  J Relig Health       Date:  2021-01-08

5.  Impact of perioperative red blood cell transfusion, anemia of cancer and global health status on the prognosis of elderly patients with endometrial and ovarian cancer.

Authors:  Katharina Anic; Mona Wanda Schmidt; Marcus Schmidt; Slavomir Krajnak; Amelie Löwe; Valerie Catherine Linz; Roxana Schwab; Wolfgang Weikel; Walburgis Brenner; Christiane Westphalen; René Rissel; Erik Kristoffer Hartmann; Roland Conradi; Annette Hasenburg; Marco Johannes Battista
Journal:  Front Oncol       Date:  2022-09-16       Impact factor: 5.738

6.  Peri-Operative Blood Transfusion Does Not Influence Overall and Disease-Free Survival After Radical Gastrectomy for Stage II/III Gastric Cancer: a Propensity Score Matching Analysis.

Authors:  Hua Xiao; Wu Liu; Hu Quan; Yongzhong Ouyang
Journal:  J Gastrointest Surg       Date:  2018-05-18       Impact factor: 3.452

  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.