Anna S Englhard1, Maximilian Wiedmann2, Georg J Ledderose1, Bryan Lemieux3, Alan Badran3, Zhongping Chen2, Christian S Betz1, Brian J Wong3,4. 1. Department of Otolaryngology-Head and Neck Surgery, Ludwig Maximilian University Munich, Munich, Germany. 2. Department of Biomedical Engineering, University of California, Irvine, Irvine, California, U.S.A. 3. Beckman Laser Institute, University of California, Irvine, Irvine, California, U.S.A. 4. Department of Otolaryngology-Head and Neck Surgery, University of California, Irvine, Irvine, California, U.S.A.
Abstract
OBJECTIVES/HYPOTHESIS: To evaluate for the first time the feasibility and methodology of long-range Fourier domain optical coherence tomography (LR-OCT) imaging of the internal nasal valve (INV) area in healthy individuals. STUDY DESIGN: Prospective individual cohort study. METHODS: For 16 individuals, OCT was performed in each nare. The angle and the cross-sectional area of the INV were measured. OCT images were compared to corresponding digital pictures recorded with a flexible endoscope. RESULTS: INV angle measured by OCT was found to be 18.3° ± 3.1° (mean ± standard deviation). The cross-sectional area was 0.65 ± 0.23 cm(2) . The INV angle measured by endoscopy was 18.8° ± 6.9°. There was no statistically significant difference between endoscopy and OCT concerning the mean INV angle (P = .778), but there was a significant difference in test precision (coefficient of variance 50% vs. 15%; P < .001). CONCLUSIONS: LR-OCT proved to be a fast and easily performed method. OCT could accurately quantify the INV area. The values of the angle and the cross-sectional area of the INV were reproducible and correlated well with the data seen with other methods. Changes in size could be reliably delineated. Endoscopy showed similar values but was significantly less precise. LEVEL OF EVIDENCE: 2b. Laryngoscope, 126:E97-E102, 2016.
OBJECTIVES/HYPOTHESIS: To evaluate for the first time the feasibility and methodology of long-range Fourier domain optical coherence tomography (LR-OCT) imaging of the internal nasal valve (INV) area in healthy individuals. STUDY DESIGN: Prospective individual cohort study. METHODS: For 16 individuals, OCT was performed in each nare. The angle and the cross-sectional area of the INV were measured. OCT images were compared to corresponding digital pictures recorded with a flexible endoscope. RESULTS: INV angle measured by OCT was found to be 18.3° ± 3.1° (mean ± standard deviation). The cross-sectional area was 0.65 ± 0.23 cm(2) . The INV angle measured by endoscopy was 18.8° ± 6.9°. There was no statistically significant difference between endoscopy and OCT concerning the mean INV angle (P = .778), but there was a significant difference in test precision (coefficient of variance 50% vs. 15%; P < .001). CONCLUSIONS:LR-OCT proved to be a fast and easily performed method. OCT could accurately quantify the INV area. The values of the angle and the cross-sectional area of the INV were reproducible and correlated well with the data seen with other methods. Changes in size could be reliably delineated. Endoscopy showed similar values but was significantly less precise. LEVEL OF EVIDENCE: 2b. Laryngoscope, 126:E97-E102, 2016.
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