Literature DB >> 26594645

Medicinal Plants: Their Use in Anticancer Treatment.

M Greenwell, P K S M Rahman.   

Abstract

Globally cancer is a disease which severely effects the human population. There is a constant demand for new therapies to treat and prevent this life-threatening disease. Scientific and research interest is drawing its attention towards naturally-derived compounds as they are considered to have less toxic side effects compared to current treatments such as chemotherapy. The Plant Kingdom produces naturally occurring secondary metabolites which are being investigated for their anticancer activities leading to the development of new clinical drugs. With the success of these compounds that have been developed into staple drugs for cancer treatment new technologies are emerging to develop the area further. New technologies include nanoparticles for nano-medicines which aim to enhance anticancer activities of plant-derived drugs by controlling the release of the compound and investigating new methods for administration. This review discusses the demand for naturally-derived compounds from medicinal plants and their properties which make them targets for potential anticancer treatments.

Entities:  

Keywords:  anticancer; cytotoxicity; epigenetics; polyphenols; secondary metabolites

Year:  2015        PMID: 26594645      PMCID: PMC4650206          DOI: 10.13040/IJPSR.0975-8232.6(10).4103-12

Source DB:  PubMed          Journal:  Int J Pharm Sci Res        ISSN: 0975-8232


  44 in total

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Journal:  Bioorg Med Chem Lett       Date:  2007-06-26       Impact factor: 2.823

2.  Anticarcinogenic activity of polyphenolic extracts from grape stems against breast, colon, renal and thyroid cancer cells.

Authors:  Despina Sahpazidou; George D Geromichalos; Dimitrios Stagos; Anna Apostolou; Serkos A Haroutounian; Aristidis M Tsatsakis; George N Tzanakakis; A Wallace Hayes; Dimitrios Kouretas
Journal:  Toxicol Lett       Date:  2014-02-06       Impact factor: 4.372

3.  Nuclear factor kappa B is a molecular target for sulforaphane-mediated anti-inflammatory mechanisms.

Authors:  E Heiss; C Herhaus; K Klimo; H Bartsch; C Gerhäuser
Journal:  J Biol Chem       Date:  2001-06-15       Impact factor: 5.157

4.  Quercetin conjugated superparamagnetic magnetite nanoparticles for in-vitro analysis of breast cancer cell lines for chemotherapy applications.

Authors:  S Rajesh Kumar; S Priyatharshni; V N Babu; D Mangalaraj; C Viswanathan; S Kannan; N Ponpandian
Journal:  J Colloid Interface Sci       Date:  2014-09-16       Impact factor: 8.128

5.  The anticancer potential of flavonoids isolated from the stem bark of Erythrina suberosa through induction of apoptosis and inhibition of STAT signaling pathway in human leukemia HL-60 cells.

Authors:  Sunil Kumar; Anup Singh Pathania; A K Saxena; R A Vishwakarma; Asif Ali; Shashi Bhushan
Journal:  Chem Biol Interact       Date:  2013-07-09       Impact factor: 5.192

6.  Green tea polyphenol epigallocatechin-3-gallate differentially modulates oxidative stress in PC12 cell compartments.

Authors:  Haider Raza; Annie John
Journal:  Toxicol Appl Pharmacol       Date:  2005-09-15       Impact factor: 4.219

Review 7.  How Taxol stabilises microtubule structure.

Authors:  L A Amos; J Löwe
Journal:  Chem Biol       Date:  1999-03

8.  Bromelain nanoparticles protect against 7,12-dimethylbenz[a]anthracene induced skin carcinogenesis in mouse model.

Authors:  Priyanka Bhatnagar; Aditya B Pant; Yogeshwer Shukla; Bhushan Chaudhari; Pradeep Kumar; Kailash C Gupta
Journal:  Eur J Pharm Biopharm       Date:  2015-01-22       Impact factor: 5.571

9.  Medicinal plants used in treatment and management of cancer in Kakamega County, Kenya.

Authors:  Dominic O Ochwang'i; Charles N Kimwele; Jemimah A Oduma; Peter K Gathumbi; James M Mbaria; Stephen G Kiama
Journal:  J Ethnopharmacol       Date:  2013-12-18       Impact factor: 4.360

Review 10.  Flavopiridol: pleiotropic biological effects enhance its anti-cancer activity.

Authors:  Elizabeth W Newcomb
Journal:  Anticancer Drugs       Date:  2004-06       Impact factor: 2.248

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  116 in total

1.  Kaempferol Induces Cell Death and Sensitizes Human Head and Neck Squamous Cell Carcinoma Cell Lines to Cisplatin.

Authors:  Mabel Catalán; Catalina Rodríguez; Ivonne Olmedo; Javiera Carrasco-Rojas; Diego Rojas; Alfredo Molina-Berríos; Mario Díaz-Dosque; José A Jara
Journal:  Adv Exp Med Biol       Date:  2021       Impact factor: 2.622

2.  Cycloartobiloxanthone Induces Human Lung Cancer Cell Apoptosis via Mitochondria-dependent Apoptotic Pathway.

Authors:  Nattanan Losuwannarak; Boonchoo Sritularak; Pithi Chanvorachote
Journal:  In Vivo       Date:  2018 Jan-Feb       Impact factor: 2.155

3.  Current Progress of Phytomedicine in Glioblastoma Therapy.

Authors:  Fahad Hassan Shah; Saad Salman; Jawaria Idrees; Fariha Idrees; Syed Turab Ali Shah; Abid Ali Khan; Bashir Ahmad
Journal:  Curr Med Sci       Date:  2021-01-11

4.  Pluronic micelles encapsulated curcumin manifests apoptotic cell death and inhibits pro-inflammatory cytokines in human breast adenocarcinoma cells.

Authors:  Foram U Vaidya; Rakesh Sharma; Sofiya Shaikh; Debes Ray; Vinod K Aswal; Chandramani Pathak
Journal:  Cancer Rep (Hoboken)       Date:  2018-09-24

5.  Antiproliferative effect of berberine on canine mammary gland cancer cell culture.

Authors:  Reyhaneh Sefidabi; Pejman Mortazavi; Saeed Hosseini
Journal:  Biomed Rep       Date:  2016-11-11

Review 6.  Anti-ovarian cancer potential of phytocompound and extract from South African medicinal plants and their role in the development of chemotherapeutic agents.

Authors:  Chella Perumal Palanisamy; Bo Cui; Hongxia Zhang; Mani Panagal; Sivagurunathan Paramasivam; Uma Chinnaiyan; Selvaraj Jeyaraman; Karthigeyan Murugesan; Mauricio Rostagno; Vijayakumar Sekar; Srinivasa Prabhu Natarajan
Journal:  Am J Cancer Res       Date:  2021-05-15       Impact factor: 6.166

7.  Berbamine suppresses cell viability and induces apoptosis in colorectal cancer via activating p53-dependent apoptotic signaling pathway.

Authors:  Heng Zhang; Yunping Jiao; Chunyang Shi; Xiao Song; Ying Chang; Yong Ren; Xiaolin Shi
Journal:  Cytotechnology       Date:  2017-09-30       Impact factor: 2.058

8.  Molecular pathways related to the control of proliferation and cell death in 786-O cells treated with plumbagin.

Authors:  Igor Alves Mancilla; Giuliana Castello Coatti; Bruna Isabela Biazi; Thalita Alves Zanetti; Adrivanio Baranoski; Lilian Areal Marques; Amanda Cristina Corveloni; Sandra Regina Lepri; Mario Sergio Mantovani
Journal:  Mol Biol Rep       Date:  2019-08-27       Impact factor: 2.316

9.  Onion Extract Encapsulated on Nano Chitosan: a Promising Anticancer Agent.

Authors:  Abdulrahman Ali Alzandi; Deyala M Naguib; Al-Shimaa M Abas
Journal:  J Gastrointest Cancer       Date:  2021-01-08

10.  Comparison of Anticancer Activity of Dorycnium pentaphyllum Extract on MCF-7 and MCF-12A Cell Line: Correlation with Invasion and Adhesion.

Authors:  Gözde Koygun; Emine Arslan; Gökhan Zengin; Giustino Orlando; Claudio Ferrante
Journal:  Biomolecules       Date:  2021-04-30
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