Literature DB >> 34094656

Anti-ovarian cancer potential of phytocompound and extract from South African medicinal plants and their role in the development of chemotherapeutic agents.

Chella Perumal Palanisamy1, Bo Cui1, Hongxia Zhang1, Mani Panagal2, Sivagurunathan Paramasivam3, Uma Chinnaiyan3, Selvaraj Jeyaraman4, Karthigeyan Murugesan5, Mauricio Rostagno6, Vijayakumar Sekar7, Srinivasa Prabhu Natarajan8.   

Abstract

Ovarian cancer (OC) accounts for the highest tumor-related mortality among the gynecologic malignancies. Most of the OC patients diagnosed with advanced-stage (III and IV) this situation creates panic and provokes an emergency to discover a new therapeutic strategy. Plants that possess medicinal properties are gaining attention as they are enriched with various chemical compounds that are potential to treat various diseases. It is a prolonged process to provide innovative and significant leads against a range of pharmacological targets for a human disease management system. Though challenges and difficulties are faced in the development of a new drug, the emergence of combinatorial chemistry is providing a new ray of hope and also, the executed effort in discovering the drug, and a chemical compound has been remarkably successful. This review discussed the role of medicinal plants that are native of South Africa in treating the Ovarian Cancer and in drug discovery. AJCR
Copyright © 2021.

Entities:  

Keywords:  Ovarian cancer; anti-ovarian cancer activity; drug development; south african medicinal plants

Year:  2021        PMID: 34094656      PMCID: PMC8167668     

Source DB:  PubMed          Journal:  Am J Cancer Res        ISSN: 2156-6976            Impact factor:   6.166


  73 in total

1.  In vitro anticancer screening of South African plants.

Authors:  G Fouche; G M Cragg; P Pillay; N Kolesnikova; V J Maharaj; J Senabe
Journal:  J Ethnopharmacol       Date:  2008-07-16       Impact factor: 4.360

2.  Sutherlandia frutescens: the meeting of science and traditional knowledge.

Authors:  Oluwaseyi M Aboyade; Gustav Styger; Diana Gibson; Gail Hughes
Journal:  J Altern Complement Med       Date:  2013-07-09       Impact factor: 2.579

3.  (-)-9'-O-(α-l-Rhamnopyranosyl)lyoniresinol from Lespedeza cuneata suppresses ovarian cancer cell proliferation through induction of apoptosis.

Authors:  Jiwon Baek; Dahae Lee; Tae Kyoung Lee; Ji Hoon Song; Ju Sung Lee; Seong Lee; Sang-Woo Yoo; Ki Sung Kang; Eunjung Moon; Sanghyun Lee; Ki Hyun Kim
Journal:  Bioorg Med Chem Lett       Date:  2017-11-28       Impact factor: 2.823

4.  Cytotoxicity of 91 Kenyan indigenous medicinal plants towards human CCRF-CEM leukemia cells.

Authors:  Leonidah K Omosa; Jacob O Midiwo; Veronica M Masila; Boniface M Gisacho; Renee Munayi; Kitur Phylis Chemutai; Gihan Elhaboob; Mohamed E M Saeed; Sami Hamdoun; Victor Kuete; Thomas Efferth
Journal:  J Ethnopharmacol       Date:  2015-12-22       Impact factor: 4.360

5.  Modulating effects of rooibos and honeybush herbal teas on the development of esophageal papillomas in rats.

Authors:  Linda Sissing; Jeanine Marnewick; Maryna de Kock; Sonja Swanevelder; Elizabeth Joubert; Wentzel Gelderblom
Journal:  Nutr Cancer       Date:  2011       Impact factor: 2.900

6.  Safety Assessment of Phytochemicals Derived from the Globalized South African Rooibos Tea ( Aspalathus linearis) through Interaction with CYP, PXR, and P-gp.

Authors:  Omer I Fantoukh; Olivia R Dale; Abidah Parveen; Mohammed F Hawwal; Zulfiqar Ali; Vamshi K Manda; Shabana I Khan; Amar G Chittiboyina; Alvaro Viljoen; Ikhlas A Khan
Journal:  J Agric Food Chem       Date:  2019-04-18       Impact factor: 5.279

7.  Inhibition of tumour promotion in mouse skin by extracts of rooibos (Aspalathus linearis) and honeybush (Cyclopia intermedia), unique South African herbal teas.

Authors:  Jeanine Marnewick; Elizabeth Joubert; Shamiel Joseph; Sonja Swanevelder; Pieter Swart; Wentzel Gelderblom
Journal:  Cancer Lett       Date:  2004-12-10       Impact factor: 8.679

Review 8.  Antiparasitic activity in Asteraceae with special attention to ethnobotanical use by the tribes of Odisha, India.

Authors:  Sujogya Kumar Panda; Walter Luyten
Journal:  Parasite       Date:  2018-03-12       Impact factor: 3.000

Review 9.  Beneficial Effects of Citrus Flavonoids on Cardiovascular and Metabolic Health.

Authors:  Ayman M Mahmoud; Rene J Hernández Bautista; Mansur A Sandhu; Omnia E Hussein
Journal:  Oxid Med Cell Longev       Date:  2019-03-10       Impact factor: 6.543

10.  Drug discovery from plant sources: An integrated approach.

Authors:  Chandrakant Katiyar; Arun Gupta; Satyajyoti Kanjilal; Shefali Katiyar
Journal:  Ayu       Date:  2012-01
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  2 in total

1.  Molecular docking and GC-MS data for the inhibition of RAD51 expression by a compound from Clerodendrum inerme L.

Authors:  Karthikeyan Kalimuthu Ayyakkalai Marikkannu; Sasireka Ganesan
Journal:  Bioinformation       Date:  2021-08-31

2.  2-Dimensional in vitro culture assessment of ovarian cancer cell line using cost effective silver nanoparticles from Macrotyloma uniflorum seed extracts.

Authors:  Kousalya Lavudi; Venkata Satya Harika; Rekha Rani Kokkanti; Swaroopa Patchigolla; Anupriya Sinha; Srinivas Patnaik; Josthna Penchalaneni
Journal:  Front Bioeng Biotechnol       Date:  2022-08-16
  2 in total

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