Literature DB >> 2658220

Phosphorothioates in molecular biology.

F Eckstein, G Gish.   

Abstract

The observation that phosphorothioate analogues of the nucleoside triphosphates are substrates for DNA- and RNA-polymerases has proven a boon for the molecular biologist. As these phosphorothioate-containing polymers are stable to degradation by nucleases and the sulfur atom confers many favourable chemical properties, several applications in molecular biology have been developed, including new methods for site-directed mutagenesis and DNA sequencing.

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Year:  1989        PMID： 2658220     DOI： 10.1016/0968-0004(89)90130-8

Source DB:  PubMed          Journal:  Trends Biochem Sci        ISSN： 0968-0004            Impact factor:   13.807


  40 in total

1.  Dimerization of HIV-1 genomic RNA of subtypes A and B: RNA loop structure and magnesium binding.

Authors:  F Jossinet; J C Paillart; E Westhof; T Hermann; E Skripkin; J S Lodmell; C Ehresmann; B Ehresmann; R Marquet
Journal:  RNA       Date:  1999-09       Impact factor: 4.942

Review 2.  Biological phosphoryl-transfer reactions: understanding mechanism and catalysis.

Authors:  Jonathan K Lassila; Jesse G Zalatan; Daniel Herschlag
Journal:  Annu Rev Biochem       Date:  2011       Impact factor: 23.643

3.  Use of nucleotide analogs by class I and class II CCA-adding enzymes (tRNA nucleotidyltransferase): deciphering the basis for nucleotide selection.

Authors:  Hyundae D Cho; Adegboyega K Oyelere; Scott A Strobel; Alan M Weiner
Journal:  RNA       Date:  2003-08       Impact factor: 4.942

4.  Structural insights into DndE from Escherichia coli B7A involved in DNA phosphorothioation modification.

Authors:  Wei Hu; Chengkun Wang; Jingdan Liang; Tianlong Zhang; Zhongpei Hu; Zhijun Wang; Wenxian Lan; Fang Li; Houming Wu; Jianping Ding; Geng Wu; Zixin Deng; Chunyang Cao
Journal:  Cell Res       Date:  2012-04-24       Impact factor: 25.617

5.  Phosphorothioate-containing RNAs show mRNA activity in the prokaryotic translation systems in vitro.

Authors:  T Ueda; H Tohda; N Chikazumi; F Eckstein; K Watanabe
Journal:  Nucleic Acids Res       Date:  1991-02-11       Impact factor: 16.971

Review 6.  Probing enzyme phosphoester interactions by combining mutagenesis and chemical modification of phosphate ester oxygens.

Authors:  James T Stivers; Rajesh Nagarajan
Journal:  Chem Rev       Date:  2006-08       Impact factor: 60.622

7.  Mutations in the 915 region of Escherichia coli 16S ribosomal RNA reduce the binding of streptomycin to the ribosome.

Authors:  D Leclerc; P Melançon; L Brakier-Gingras
Journal:  Nucleic Acids Res       Date:  1991-07-25       Impact factor: 16.971

8.  DNA phosphorothioation is widespread and quantized in bacterial genomes.

Authors:  Lianrong Wang; Shi Chen; Kevin L Vergin; Stephen J Giovannoni; Simon W Chan; Michael S DeMott; Koli Taghizadeh; Otto X Cordero; Michael Cutler; Sonia Timberlake; Eric J Alm; Martin F Polz; Jarone Pinhassi; Zixin Deng; Peter C Dedon
Journal:  Proc Natl Acad Sci U S A       Date:  2011-02-01       Impact factor: 11.205

9.  Maleimide-mediated protein conjugates of a nucleoside triphosphate gamma-S and an internucleotide phosphorothioate diester.

Authors:  A S Karim; C S Johansson; J K Weltman
Journal:  Nucleic Acids Res       Date:  1995-06-11       Impact factor: 16.971

10.  Dissecting RNA folding by nucleotide analog interference mapping (NAIM).

Authors:  Christina Waldsich
Journal:  Nat Protoc       Date:  2008       Impact factor: 13.491
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